| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Dark Knight | $1,355,305 | - | 90 | - | $15,058 | $1,412,834 | 1 | Warner Bros. | true | false |
| 2 | 2 | Mamma Mia! | $500,245 | -45.5% | 106 | - | $4,719 | $2,498,188 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | 1 | Hancock | $395,396 | -57.5% | 91 | - | $4,345 | $3,832,051 | 3 | Sony Pictures Releasing | false | false |
| 4 | 3 | Kung Fu Panda | $282,024 | -68.6% | 189 | - | $1,492 | $4,054,144 | 3 | Universal Pictures International (UPI) | false | false |
| 5 | 6 | Sex and the City | $146,501 | -50.2% | 90 | -10 | $1,627 | $5,567,864 | 7 | Paradiso Entertainment | false | false |
| 6 | 5 | The Chronicles of Narnia: Prince Caspian | $110,634 | -64.5% | 171 | -3 | $646 | $2,567,866 | 4 | Walt Disney Pictures | false | false |
| 7 | 4 | De brief voor de koning | $110,013 | -72.8% | 103 | - | $1,068 | $861,029 | 2 | Benelux Film Distributors | false | false |
| 8 | 8 | The Strangers | $89,733 | -49.7% | 39 | +4 | $2,300 | $383,949 | 2 | RCV Film Distribution | false | false |
| 9 | 9 | Indiana Jones and the Kingdom of the Crystal Skull | $68,258 | -54.9% | 54 | -10 | $1,264 | $6,655,444 | 10 | Universal Pictures International (UPI) | false | false |
| 10 | 7 | Hoe overleef ik...? | $50,545 | -72.2% | 93 | - | $543 | $2,062,531 | 5 | Warner Bros. | false | false |
| 11 | 11 | 21 | $43,040 | -54.6% | 33 | -7 | $1,304 | $1,160,996 | 5 | Sony Pictures Releasing | false | false |
| 12 | 13 | Into the Wild | $27,371 | -49% | 23 | +3 | $1,190 | $1,188,547 | 14 | A-Film Distribution | false | false |
| 13 | 12 | I've Loved You So Long | $22,266 | -63.9% | 20 | +1 | $1,113 | $639,925 | 8 | Benelux Film Distributors | false | false |
| 14 | 10 | Snuf de hond in oorlogstijd | $22,189 | -76.6% | 63 | -1 | $352 | $594,135 | 5 | RCV Film Distribution | false | false |
| 15 | 14 | What Happens in Vegas | $11,776 | -71.5% | 12 | -10 | $981 | $4,169,150 | 12 | Warner Bros. | false | false |
| 16 | 18 | The Night of the Sunflowers | $10,575 | -64.5% | 12 | - | $881 | $93,219 | 3 | Benelux Film Distributors | false | false |
| 17 | 19 | The Incredible Hulk | $9,848 | -59.7% | 9 | -7 | $1,094 | $1,331,566 | 6 | Universal Pictures International (UPI) | false | false |
| 18 | 15 | In Bruges | $9,755 | -75.5% | 13 | -1 | $750 | $284,702 | 5 | Universal Pictures International (UPI) | false | false |
| 19 | 17 | Forgetting Sarah Marshall | $9,386 | -70.8% | 12 | -6 | $782 | $389,874 | 4 | Universal Pictures International (UPI) | false | false |
| 20 | - | Never Back Down | $9,069 | - | 6 | - | $1,511 | $11,542 | 1 | Paradiso Entertainment | true | false |
