| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Hancock | $8,555 | -2.4% | 6 | - | $1,425 | $53,712 | 3 | Tuck | false | false |
| 2 | 3 | Sex and the City | $7,909 | +0.5% | 6 | - | $1,318 | $419,454 | 6 | Tuck | false | false |
| 3 | - | Meet Dave | $6,945 | - | 4 | - | $1,736 | $9,954 | 1 | Tuck | true | false |
| 4 | 4 | Wanted | $5,701 | -20.7% | 4 | - | $1,425 | $25,381 | 2 | Taramount Film | false | false |
| 5 | 2 | Kung Fu Panda | $5,354 | -33.8% | 7 | - | $764 | $56,397 | 3 | Taramount Film | false | false |
| 6 | 5 | Indiana Jones and the Kingdom of the Crystal Skull | $2,174 | -21.8% | 9 | - | $241 | $226,931 | 8 | Taramount Film | false | false |
| 7 | 7 | The Chronicles of Narnia: Prince Caspian | $2,072 | +6.7% | 7 | - | $296 | $35,065 | 4 | Taramount Film | false | false |
| 8 | 9 | What Happens in Vegas | $1,014 | +60.2% | 5 | - | $202 | $89,657 | 10 | Tuck | false | false |
| 9 | 10 | The Incredible Hulk | $758 | +33.2% | 4 | - | $189 | $34,411 | 6 | Taramount Film | false | false |
| 10 | 11 | The Happening | $426 | -19.5% | 3 | - | $142 | $21,428 | 6 | Tuck | false | false |
| 11 | 28 | Shadows | $270 | +900% | 2 | - | $135 | $8,404 | 14 | Mirius | false | false |
| 12 | 26 | Horton Hears a Who! | $197 | +556.7% | 6 | - | $32 | $75,491 | 18 | Tuck | false | false |
| 13 | 13 | Step Up 2: The Streets | $162 | -26% | 3 | - | $54 | $19,234 | 13 | Mirius | false | false |
| 14 | 30 | 21 | $120 | +605.9% | 5 | - | $24 | $38,684 | 12 | Tuck | false | false |
| 15 | 12 | 10,000 BC | $76 | -84.2% | 5 | - | $15 | $90,514 | 18 | Tuck | false | false |
| 16 | 32 | The Darjeeling Limited | $59 | +1,080% | 1 | - | $59 | $18,743 | 17 | Tuck | false | false |
| 17 | 14 | Street Kings | $56 | -66.7% | 3 | - | $18 | $39,427 | 14 | Tuck | false | false |
| 18 | 15 | Iron Man | $44 | -66.9% | 4 | - | $11 | $39,427 | 11 | Taramount Film | false | false |
| 19 | 29 | Sweeney Todd: The Demon Barber of Fleet Street | $29 | +52.6% | 2 | - | $14 | $44,466 | 20 | Tuck | false | false |
| 20 | - | P.S. I Love You | $25 | - | 2 | - | $12 | $31,989 | 31 | Mirius | false | false |
| 21 | - | The Spiderwick Chronicles | $17 | - | 6 | - | $2 | $23,371 | 14 | Taramount Film | false | false |
| 22 | 24 | Fool's Gold | $14 | -58.8% | 5 | - | $2 | $62,857 | 15 | Tuck | false | false |
