| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | WALL·E | $263,536 | - | 86 | - | $3,064 | $263,536 | 1 | Ster-Kinekor Pictures | true | false |
| 2 | 1 | Hancock | $253,751 | -59.5% | 91 | - | $2,788 | $1,174,070 | 2 | Ster-Kinekor Pictures | false | false |
| 3 | - | Wanted | $251,547 | - | 73 | - | $3,445 | $251,547 | 1 | United International Pictures | true | false |
| 4 | 2 | Kung Fu Panda | $179,821 | -37.2% | 91 | -15 | $1,976 | $1,660,461 | 3 | United International Pictures | false | false |
| 5 | 3 | Get Smart | $101,681 | -53.6% | 64 | -1 | $1,588 | $463,877 | 2 | NuMetro Distribution | false | false |
| 6 | 4 | College Road Trip | $44,035 | -27.4% | 35 | -5 | $1,258 | $531,971 | 4 | Ster-Kinekor Pictures | false | false |
| 7 | 6 | Harold & Kumar Escape from Guantanamo Bay | $29,548 | -37.8% | 25 | -5 | $1,181 | $281,832 | 3 | NuMetro Distribution | false | false |
| 8 | 5 | The Incredible Hulk | $23,683 | -52.7% | 48 | -17 | $493 | $897,596 | 5 | United International Pictures | false | false |
| 9 | 7 | What Happens in Vegas | $22,497 | -39.2% | 34 | -16 | $661 | $1,424,863 | 9 | NuMetro Distribution | false | false |
| 10 | 10 | Sex and the City | $22,497 | -8.9% | 34 | +5 | $661 | $923,502 | 7 | NuMetro Distribution | false | false |
| 11 | 8 | The Chronicles of Narnia: Prince Caspian | $17,857 | -44.6% | 33 | -24 | $541 | $1,026,102 | 6 | Ster-Kinekor Pictures | false | false |
| 12 | 11 | Thoda Pyaar Thoda Magic | $10,785 | -26.8% | 8 | - | $1,348 | $68,994 | 3 | NuMetro Distribution | false | false |
| 13 | - | All the Boys Love Mandy Lane | $8,469 | - | 15 | - | $564 | $8,469 | 1 | Ster-Kinekor Pictures | true | false |
| 14 | 13 | Definitely, Maybe | $7,517 | -44.7% | 10 | -10 | $751 | $378,348 | 6 | United International Pictures | false | false |
| 15 | 15 | Bella | $7,188 | -22.5% | 7 | - | $1,026 | $22,273 | 2 | Ster-Kinekor Pictures | false | false |
| 16 | 9 | Forgetting Sarah Marshall | $6,410 | -75.9% | 18 | -25 | $356 | $285,062 | 4 | United International Pictures | false | false |
| 17 | 16 | Married Life | $5,823 | -1.4% | 10 | +2 | $582 | $66,400 | 5 | NuMetro Distribution | false | false |
| 18 | 12 | The Happening | $5,531 | -60.8% | 14 | -15 | $395 | $384,580 | 5 | NuMetro Distribution | false | false |
| 19 | - | Paris, Je T'aime | $4,506 | - | 6 | - | $751 | $59,395 | 7 | NuMetro Distribution | false | false |
| 20 | 14 | Indiana Jones and the Kingdom of the Crystal Skull | $4,433 | -62.8% | 11 | -9 | $403 | $1,169,701 | 8 | United International Pictures | false | false |
| 21 | 17 | Jaane Tu... Ya Jaane Na | $3,910 | -22.3% | 4 | - | $977 | $13,191 | 2 | Ster-Kinekor Pictures | false | false |
| 22 | 18 | Love Story 2050 | $3,070 | -38.4% | 7 | - | $438 | $13,177 | 2 | Ster-Kinekor Pictures | false | false |
| 23 | 19 | Iron Man | $1,767 | -60.2% | 9 | -4 | $196 | $1,464,664 | 11 | United International Pictures | false | false |
| 24 | 24 | Made of Honor | $426 | -59.7% | 1 | -4 | $426 | $838,531 | 11 | United International Pictures | false | false |
| 25 | 23 | First Sunday | $297 | -80.7% | 1 | -2 | $297 | $172,832 | 12 | United International Pictures | false | false |
