| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Wanted | $653,884 | - | 80 | - | $8,173 | $653,884 | 1 | - | true | false |
| 2 | 1 | Sex and the City | $154,985 | -67.5% | 46 | - | $3,369 | $836,197 | 2 | Kinomania | false | false |
| 3 | 2 | You Don't Mess with the Zohan | $77,698 | -57.5% | 55 | - | $1,412 | $345,068 | 2 | - | false | false |
| 4 | - | Over Her Dead Body | $44,740 | - | 17 | - | $2,631 | $44,740 | 1 | JRC Film | true | false |
| 5 | 3 | Kung Fu Panda | $44,650 | -60.1% | 80 | - | $558 | $1,837,639 | 4 | - | false | false |
| 6 | 4 | The Incredible Hulk | $14,622 | -85.6% | 55 | -17 | $265 | $527,103 | 3 | - | false | false |
| 7 | 6 | A Prueba De Hombres | $9,467 | -69.1% | 24 | -4 | $394 | $192,899 | 3 | Central Partnership | false | false |
| 8 | 5 | The Happening | $9,151 | -81.1% | 41 | -11 | $223 | $267,920 | 3 | Gemini Film | false | false |
| 9 | 7 | Indiana Jones and the Kingdom of the Crystal Skull | $7,194 | -37% | 27 | -14 | $266 | $1,595,056 | 6 | - | false | false |
| 10 | 8 | My Mom's New Boyfriend | $6,738 | -10.6% | 16 | +4 | $421 | $140,504 | 4 | Paradise Group | false | false |
| 11 | 10 | Speed Racer | $3,233 | -21% | 19 | -7 | $170 | $110,375 | 5 | Kinomania | false | false |
| 12 | 12 | 21 | $426 | -74.6% | 6 | -2 | $71 | $210,574 | 5 | - | false | false |
| 13 | 11 | The Chronicles of Narnia: Prince Caspian | $407 | -76.8% | 2 | -11 | $203 | $1,062,367 | 7 | - | false | false |
| 14 | 13 | What Happens in Vegas | $350 | -6.2% | 2 | - | $175 | $864,619 | 8 | Gemini Film | false | false |
| 15 | 16 | Iron Man | $68 | +1.5% | 1 | - | $68 | $828,937 | 9 | - | false | false |
