| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Chronicles of Narnia: Prince Caspian | $145,246 | - | 31 | - | $4,685 | $169,021 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Sex and the City | $104,037 | -28.3% | 77 | +2 | $1,351 | $3,093,185 | 5 | Warner Bros. | false | false |
| 3 | 2 | Indiana Jones and the Kingdom of the Crystal Skull | $86,344 | -22% | 64 | -27 | $1,349 | $5,264,453 | 6 | Universal Pictures International (UPI) | false | false |
| 4 | 4 | 21 | $69,131 | +25.2% | 26 | -7 | $2,658 | $605,535 | 4 | Walt Disney Pictures | false | false |
| 5 | 19 | Welcome to the Sticks | $62,160 | +1,642.6% | 25 | +20 | $2,486 | $5,200,371 | 18 | Pathé | false | false |
| 6 | 3 | The Happening | $57,043 | -21.9% | 44 | -4 | $1,296 | $447,066 | 3 | 20th Century Fox International | false | false |
| 7 | 5 | Forgetting Sarah Marshall | $37,155 | -17.2% | 21 | -9 | $1,769 | $275,982 | 3 | Universal Pictures International (UPI) | false | false |
| 8 | 6 | Made of Honor | $33,147 | -24.3% | 30 | -1 | $1,104 | $821,249 | 7 | Walt Disney Pictures | false | false |
| 9 | 7 | What Happens in Vegas | $21,857 | +27.3% | 23 | +3 | $950 | $2,171,997 | 8 | 20th Century Fox International | false | false |
| 10 | - | 2 Alone in Paris | $20,606 | - | 7 | - | $2,943 | $29,149 | 1 | JMH Distribution | true | false |
| 11 | - | Street Kings | $19,768 | - | 12 | - | $1,647 | $695,069 | 11 | 20th Century Fox International | false | false |
| 12 | 9 | The Wave | $10,783 | +6.5% | 22 | -1 | $490 | $854,605 | 9 | Rialto Distribution | false | false |
| 13 | - | Waltz with Bashir | $9,538 | - | 5 | - | $1,907 | $10,460 | 1 | Frenetic Films | true | false |
| 14 | 8 | The Nanny Diaries | $7,949 | -41.6% | 8 | - | $993 | $77,261 | 3 | Ascot Elite Entertainment Group | false | false |
| 15 | 10 | Dan in Real Life | $6,545 | -32.2% | 9 | - | $727 | $21,262 | 2 | Warner Bros. | false | false |
| 16 | 14 | The Game Plan | $5,482 | +17.8% | 18 | - | $304 | $373,633 | 9 | Walt Disney Pictures | false | false |
| 17 | 17 | The Kite Runner | $5,087 | +34.6% | 3 | -1 | $1,695 | $3,089,289 | 24 | Universal Pictures International (UPI) | false | false |
| 18 | - | Interview | $4,484 | - | 3 | - | $1,494 | $15,147 | 43 | Rialto Distribution | false | false |
| 19 | 28 | No Country for Old Men | $4,319 | +772.5% | 2 | - | $2,159 | $2,214,308 | 23 | Universal Pictures International (UPI) | false | false |
| 20 | 11 | The Incredible Hulk | $4,167 | -44.9% | 4 | - | $1,041 | $18,330 | 2 | Universal Pictures International (UPI) | false | false |
| 21 | - | Julia | $3,901 | - | 2 | - | $1,950 | $49,638 | 15 | Frenetic Films | false | false |
| 22 | 26 | Iron Man | $2,491 | +29.1% | 5 | -13 | $498 | $1,359,471 | 9 | Universal Pictures International (UPI) | false | false |
| 23 | 27 | The Other Boleyn Girl | $482 | -39.9% | 3 | - | $160 | $901,811 | 17 | Universal Pictures International (UPI) | false | false |
| 24 | 29 | Superhero Movie | $215 | +20.8% | 1 | - | $215 | $27,092 | 7 | Ascot Elite Entertainment Group | false | false |
