| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Incredible Hulk | $6,333,915 | - | 484 | - | $13,086 | $6,333,897 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Sex and the City | $3,479,671 | -42.7% | 470 | +1 | $7,403 | $39,561,528 | 3 | Entertainment Film Distributors | false | false |
| 3 | 2 | Indiana Jones and the Kingdom of the Crystal Skull | $3,425,645 | -34.9% | 503 | -32 | $6,810 | $69,275,620 | 4 | Paramount Pictures International | false | false |
| 4 | - | The Happening | $3,177,059 | - | 390 | - | $8,146 | $3,177,059 | 1 | 20th Century Fox International | true | false |
| 5 | 3 | Superhero Movie | $1,003,679 | -40.1% | 393 | -3 | $2,553 | $3,283,048 | 2 | Momentum Pictures | false | false |
| 6 | 5 | Gone Baby Gone | $479,768 | -30.6% | 214 | -45 | $2,241 | $1,712,542 | 2 | Walt Disney Pictures | false | false |
| 7 | 4 | Prom Night | $474,882 | -52.5% | 271 | -14 | $1,752 | $1,979,095 | 2 | Sony Pictures Releasing | false | false |
| 8 | 6 | What Happens in Vegas | $258,408 | -54.8% | 166 | -109 | $1,556 | $14,940,798 | 6 | 20th Century Fox International | false | false |
| 9 | 7 | Iron Man | $250,164 | -55.4% | 244 | -97 | $1,025 | $33,033,154 | 7 | Paramount Pictures International | false | false |
| 10 | 9 | Mongol: The Rise of Genghis Khan | $249,924 | -31.5% | 80 | +4 | $3,124 | $849,753 | 2 | The Works UK Distribution | false | false |
| 11 | - | Dasavatharam | $246,677 | - | 19 | - | $12,983 | $246,677 | 1 | Ayngaran International | true | false |
| 12 | - | Priceless | $244,176 | - | 61 | - | $4,002 | $244,176 | 1 | Icon Film Distribution | true | false |
| 13 | - | Mere Baap Pehle Aap | $199,469 | - | 31 | - | $6,434 | $199,469 | 1 | - | true | false |
| 14 | 11 | Nim's Island | $130,740 | -33.3% | 268 | -76 | $487 | $7,179,068 | 7 | Universal Pictures International (UPI) | false | false |
| 15 | - | In Search of a Midnight Kiss | $102,854 | - | 28 | - | $3,673 | $102,854 | 1 | Vertigo Films | true | false |
| 16 | 8 | Sarkar Raj | $100,191 | -72.9% | 48 | -1 | $2,087 | $605,289 | 2 | Eros Worldwide | false | false |
| 17 | 10 | Harold & Kumar Escape from Guantanamo Bay | $61,082 | -72.1% | 64 | -117 | $954 | $1,262,827 | 3 | Entertainment Film Distributors | false | false |
| 18 | 19 | Underdog | $18,943 | +18.5% | 35 | -4 | $541 | $2,847,937 | 20 | Walt Disney Pictures | false | false |
| 19 | 16 | Persepolis | $18,369 | -37% | 10 | -8 | $1,836 | $1,638,575 | 8 | Optimum Releasing | false | false |
| 20 | 12 | Speed Racer | $17,720 | -83.8% | 75 | -87 | $236 | $3,126,301 | 6 | Warner Bros. | false | false |
| 21 | 14 | Caramel | $15,338 | -50.7% | 12 | -9 | $1,278 | $820,732 | 5 | Momentum Pictures | false | false |
| 22 | 13 | Forgetting Sarah Marshall | $12,632 | -77.1% | 15 | -43 | $842 | $14,752,640 | 8 | Universal Pictures International (UPI) | false | false |
| 23 | 18 | Jules and Jim 2008 Re-release | $11,820 | -31.6% | 6 | +1 | $1,970 | $128,793 | 3 | British Film Institute (BFI) | false | false |
| 24 | 21 | Happy-Go-Lucky | $10,115 | -34% | 11 | -6 | $919 | $2,990,557 | 9 | Momentum Pictures | false | false |
| 25 | - | The Passionate Friends | $9,749 | - | 13 | - | $749 | $18,688 | 2 | British Film Institute (BFI) | false | false |
| 26 | 15 | Let's Get Lost | $9,033 | -70.4% | 8 | -2 | $1,129 | $58,744 | 2 | - | false | false |
| 27 | 20 | Made of Honor | $6,377 | -58.7% | 3 | -17 | $2,125 | $4,623,245 | 7 | Sony Pictures Releasing | false | false |
| 28 | 29 | The Game Plan | $6,210 | +21.3% | 16 | -5 | $388 | $8,267,792 | 15 | Walt Disney Pictures | false | false |
| 29 | 27 | Heartbeat Detector | $6,076 | -13.4% | 5 | +2 | $1,215 | $135,252 | 5 | Trinity Filmed Entertainment | false | false |
| 30 | 23 | California Dreamin' | $4,014 | -57.6% | 1 | -4 | $4,014 | $49,663 | 3 | Artificial Eye | false | false |
| 31 | 26 | The Diving Bell and the Butterfly | $3,973 | -45.8% | 3 | -8 | $1,324 | $1,743,650 | 19 | Pathé | false | false |
| 32 | 28 | Smart People | $3,761 | -33.2% | 7 | -1 | $537 | $389,437 | 5 | Icon Film Distribution | false | false |
| 33 | - | U2 3D | $2,603 | - | 2 | - | $1,301 | $1,407,158 | 17 | Revolver Entertainment | false | false |
| 34 | - | Summer 2007 | $2,398 | - | 7 | - | $342 | $2,398 | 1 | - | true | false |
| 35 | 63 | Grindhouse | $2,338 | +5,894.9% | 2 | +1 | $1,169 | $192,369 | 12 | Momentum Pictures | false | false |
| 36 | 34 | XXY | $2,334 | -32.1% | 2 | -2 | $1,167 | $112,264 | 6 | Peccadillo Pictures | false | false |
| 37 | - | Taxi to the Dark Side | $2,157 | - | 1 | - | $2,157 | $2,157 | 1 | Revolver Entertainment | true | false |
| 38 | 38 | My Brother is an Only Child | $2,114 | -16.3% | 4 | -2 | $528 | $635,478 | 11 | Revolver Entertainment | false | false |
| 39 | 37 | Welcome to the Sticks | $1,826 | -37.6% | 2 | -1 | $913 | $200,646 | 11 | Pathé | false | false |
| 40 | 35 | Lars and the Real Girl | $1,742 | -44.1% | 2 | -2 | $871 | $858,546 | 13 | Verve Pictures | false | false |
| 41 | 54 | Shotgun Stories | $1,723 | +198.6% | 4 | +2 | $430 | $30,415 | 4 | Vertigo Films | false | false |
| 42 | 47 | You, the Living | $1,701 | -0.4% | 3 | +2 | $567 | $193,465 | 12 | Artificial Eye | false | false |
| 43 | 56 | Love in the Time of Cholera | $1,653 | +878.1% | 3 | +2 | $551 | $731,049 | 13 | Momentum Pictures | false | false |
| 44 | 41 | Cassandra's Dream | $1,217 | -41.2% | 2 | - | $608 | $215,145 | 4 | Optimum Releasing | false | false |
| 45 | - | Irina Palm | $1,133 | - | 2 | - | $566 | $1,133 | 1 | Soda Pictures | true | false |
| 46 | 40 | The Ugly Duckling and Me! | $1,043 | -55.3% | 4 | -6 | $260 | $818,133 | 50 | Eclipse Pictures | false | false |
| 47 | 52 | Son of Rambow | $995 | +1.6% | 3 | +1 | $331 | $8,129,905 | 11 | Optimum Releasing | false | false |
| 48 | 43 | Where in the World Is Osama Bin Laden? | $925 | -53.6% | 3 | -1 | $308 | $137,407 | 6 | Optimum Releasing | false | false |
| 49 | - | I'm a Cyborg, But That's OK | $903 | - | 1 | - | $903 | $25,706 | 11 | Tartan | false | false |
| 50 | 51 | Charlie Bartlett | $894 | -14.9% | 2 | - | $447 | $382,081 | 5 | Verve Pictures | false | false |
| 51 | 60 | Terror's Advocate | $720 | +835.1% | 1 | - | $720 | $35,887 | 5 | Artificial Eye | false | false |
| 52 | 39 | Private Property | $685 | -72.8% | 2 | -1 | $342 | $50,130 | 9 | Soda Pictures | false | false |
| 53 | - | The 39 Steps 2008 Re-release | $600 | - | 1 | - | $600 | $51,711 | 10 | Park Circus | false | false |
| 54 | 55 | Manufactured Landscapes | $590 | +208.9% | 1 | - | $590 | $39,846 | 6 | British Film Institute (BFI) | false | false |
| 55 | 32 | Welcome Home, Roscoe Jenkins | $467 | -87.4% | 2 | -6 | $233 | $126,464 | 3 | Universal Pictures International (UPI) | false | false |
| 56 | 42 | The Last Mistress | $411 | -80.1% | 1 | -3 | $411 | $78,659 | 10 | Artificial Eye | false | false |
| 57 | 49 | Funny Games | $385 | -72.5% | 2 | -1 | $192 | $402,675 | 11 | Tartan | false | false |
| 58 | 36 | The Bank Job | $202 | -93.5% | 1 | - | $202 | $7,949,303 | 16 | Lionsgate | false | false |
| 59 | 58 | In Memory of My Father | $111 | -28.8% | 1 | - | $111 | $603 | 2 | Scanbox Entertainment | false | false |
| 60 | - | My Blueberry Nights | $66 | - | 1 | - | $66 | $553,574 | 17 | Optimum Releasing | false | false |
| 61 | - | The Air I Breathe | $39 | - | 1 | - | $39 | $6,827 | 5 | Pathé | false | false |
| 62 | 46 | The Orphanage | $39 | -97.8% | 1 | - | $39 | $3,413,967 | 13 | Optimum Releasing | false | false |
| 63 | 57 | Vexille | $39 | -76.1% | 1 | - | $39 | $6,377 | 6 | Momentum Pictures | false | false |
