| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Chronicles of Narnia: Prince Caspian | $1,458,719 | - | 103 | - | $14,162 | $1,463,297 | 1 | Walt Disney Pictures | true | false |
| 2 | - | Sex and the City | $496,109 | - | 55 | - | $9,020 | $497,870 | 1 | Distribution Company | true | false |
| 3 | 1 | Indiana Jones and the Kingdom of the Crystal Skull | $294,485 | -34.7% | 88 | -53 | $3,346 | $2,707,999 | 4 | United International Pictures | false | false |
| 4 | 4 | The Mist | $114,280 | -16.7% | 31 | - | $3,686 | $279,113 | 2 | Distribution Company | false | false |
| 5 | 2 | Cassandra's Dream | $113,461 | -34.9% | 22 | -8 | $5,157 | $325,685 | 2 | Alfa Films | false | false |
| 6 | 5 | Made of Honor | $88,409 | -25.3% | 30 | - | $2,946 | $228,764 | 2 | Sony Pictures Releasing | false | false |
| 7 | 3 | Speed Racer | $73,453 | -51.9% | 75 | -19 | $979 | $2,111,837 | 6 | Warner Bros. | false | false |
| 8 | 6 | What Happens in Vegas | $70,632 | -18.1% | 29 | -1 | $2,435 | $645,456 | 5 | 20th Century Fox International | false | false |
| 9 | - | Aniceto | $61,783 | - | 32 | - | $1,930 | $61,783 | 1 | Primer Plano Film Group | true | false |
| 10 | 7 | Death at a Funeral | $60,195 | -25.9% | 25 | -8 | $2,407 | $1,989,954 | 15 | Compañía General de la Imagen (CGI) | false | false |
| 11 | 8 | 88 Minutes | $40,072 | -44.8% | 25 | -6 | $1,602 | $270,139 | 3 | Distribution Company | false | false |
| 12 | 9 | The Oxford Murders | $33,178 | -43.2% | 16 | -7 | $2,073 | $540,844 | 6 | Pachamama Cine | false | false |
| 13 | 11 | The Counterfeiters | $17,084 | -55.1% | 10 | -12 | $1,708 | $335,830 | 5 | Alfa Films | false | false |
| 14 | 16 | Heartbeat Detector | $16,391 | +13.4% | 3 | - | $5,463 | $34,710 | 2 | Zeta Films | false | false |
| 15 | 13 | The Nest | $10,284 | -59.8% | 18 | -18 | $571 | $985,895 | 8 | Distribution Company | false | false |
| 16 | 14 | Shutter | $6,526 | -73.4% | 11 | -14 | $593 | $473,952 | 9 | 20th Century Fox International | false | false |
| 17 | 10 | Iron Man | $6,511 | -84.9% | 13 | -46 | $500 | $1,585,736 | 7 | United International Pictures | false | false |
| 18 | 18 | In the Valley of Elah | $6,363 | -49.6% | 6 | -6 | $1,060 | $329,244 | 11 | Alfa Films | false | false |
| 19 | 19 | Conversations with My Gardener | $5,864 | -53% | 4 | -7 | $1,466 | $214,654 | 8 | Alfa Films | false | false |
| 20 | 22 | Mrs Palfrey at the Claremont 2008 Re-release | $4,554 | -32.2% | 2 | -1 | $2,277 | $62,630 | 5 | Primer Plano Film Group | false | false |
| 21 | 12 | Awake | $4,372 | -85.7% | 8 | -23 | $546 | $261,257 | 5 | Distribution Company | false | false |
| 22 | - | La león | $3,718 | - | 4 | - | $929 | $3,718 | 1 | 791 Cine | true | false |
| 23 | 17 | The Unknown Woman | $3,623 | -74.7% | 3 | -13 | $1,207 | $145,863 | 4 | Impacto Cine | false | false |
| 24 | 15 | 21 | $3,244 | -83.3% | 8 | -21 | $405 | $724,499 | 9 | Sony Pictures Releasing | false | false |
| 25 | 20 | Lamb of God | $2,186 | -82.4% | 4 | -9 | $546 | $147,573 | 6 | Alfa Films | false | false |
| 26 | 31 | Caramel | $2,077 | -3.7% | 3 | - | $692 | $230,499 | 12 | Alfa Films | false | false |
| 27 | 25 | Odette Toulemonde | $1,704 | -65.8% | 2 | -4 | $852 | $29,620 | 3 | Notro Films | false | false |
| 28 | 24 | Two Days in Paris | $1,513 | -72.4% | 2 | -3 | $756 | $373,612 | 12 | Impacto Cine | false | false |
| 29 | 23 | Street Kings | $991 | -83.4% | 5 | -14 | $198 | $246,553 | 8 | 20th Century Fox International | false | false |
| 30 | 35 | U2 3D | $767 | -40.1% | 1 | - | $767 | $156,483 | 12 | IMAX | false | false |
| 31 | 27 | The Savages | $464 | -86.7% | 2 | -9 | $232 | $118,319 | 7 | 20th Century Fox International | false | false |
| 32 | 28 | Untraceable | $390 | -87.6% | 3 | -3 | $130 | $201,569 | 8 | Sony Pictures Releasing | false | false |
| 33 | 43 | No Country for Old Men | $386 | +5.5% | 1 | - | $386 | $998,814 | 15 | Walt Disney Pictures | false | false |
| 34 | 37 | Evening | $361 | -64.8% | 1 | -5 | $361 | $193,691 | 10 | Impacto Cine | false | false |
| 35 | 34 | The Game Plan | $346 | -75.5% | 4 | -3 | $86 | $1,501,466 | 18 | Walt Disney Pictures | false | false |
| 36 | 21 | Love by Accident | $245 | -96.9% | 1 | -7 | $245 | $39,247 | 3 | Primer Plano Film Group | false | false |
| 37 | 46 | Jumper | $181 | -39.1% | 1 | -1 | $181 | $614,752 | 11 | 20th Century Fox International | false | false |
| 38 | 30 | The Orphanage | $164 | -93.5% | 1 | -3 | $164 | $751,675 | 14 | CDI Films | false | false |
| 39 | 38 | The Ugly Duckling and Me! | $125 | -83.3% | 2 | -3 | $62 | $78,706 | 13 | - | false | false |
| 40 | - | Rain | $116 | - | 1 | - | $116 | $164,286 | 13 | Walt Disney Pictures | false | false |
| 41 | 52 | The Water Horse | $94 | +56.7% | 1 | - | $94 | $609,072 | 19 | Sony Pictures Releasing | false | false |
| 42 | 42 | The Spiderwick Chronicles | $92 | -76.6% | 1 | -2 | $92 | $685,778 | 13 | United International Pictures | false | false |
| 43 | 51 | Alvin and the Chipmunks | $92 | +37.3% | 1 | - | $92 | $824,029 | 24 | 20th Century Fox International | false | false |
| 44 | 44 | The Hunting Party | $78 | -78.5% | 1 | -1 | $78 | $317,644 | 13 | Distribution Company | false | false |
| 45 | 39 | Lust, Caution | $73 | -89.1% | 1 | - | $73 | $61,402 | 7 | Distribution Company | false | false |
| 46 | 53 | Enchanted | $41 | -25.5% | 1 | - | $41 | $2,862,070 | 24 | Walt Disney Pictures | false | false |
| 47 | 57 | Atonement | $38 | +442.9% | 1 | - | $38 | $528,522 | 19 | United International Pictures | false | false |
| 48 | 36 | We Own the Night | $38 | -96.5% | 1 | -2 | $38 | $87,020 | 7 | CDI Films | false | false |
| 49 | 54 | Underdog | $30 | +50% | 1 | - | $30 | $878,400 | 37 | Walt Disney Pictures | false | false |
| 50 | 45 | 10,000 BC | $20 | -94.5% | 1 | -1 | $20 | $2,262,479 | 15 | Warner Bros. | false | false |
| 51 | 55 | Juno | $11 | -15.4% | 1 | - | $11 | $478,605 | 18 | Alfa Films | false | false |
