| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Kung Fu Panda | $569,267 | - | 19 | - | $29,961 | $569,267 | 1 | N/A | true | false |
| 2 | - | The Happening | $238,078 | - | 19 | - | $12,530 | $238,078 | 1 | N/A | true | false |
| 3 | 2 | Can't Complain | $178,270 | -47.1% | 16 | -1 | $11,141 | $657,323 | 2 | N/A | false | false |
| 4 | - | Never Back Down | $161,073 | - | 19 | - | $8,477 | $161,073 | 1 | N/A | true | false |
| 5 | 1 | The Chronicles of Narnia: Prince Caspian | $138,192 | -67.1% | 20 | -9 | $6,909 | $672,012 | 2 | N/A | false | false |
| 6 | 3 | The Forbidden Kingdom | $78,230 | -62.4% | 16 | -9 | $4,889 | $1,169,842 | 3 | N/A | false | false |
| 7 | 4 | The Bank Job | $62,655 | -64.3% | 16 | -2 | $3,915 | $295,104 | 2 | N/A | false | false |
| 8 | 5 | Indiana Jones and the Kingdom of the Crystal Skull | $40,445 | -56.1% | 7 | -8 | $5,777 | $1,423,521 | 4 | N/A | false | false |
| 9 | 7 | What Happens in Vegas | $16,495 | -53.7% | 2 | -3 | $8,247 | $670,867 | 5 | N/A | false | false |
| 10 | 9 | Iron Man | $9,181 | -67.9% | 3 | -6 | $3,060 | $1,798,407 | 7 | N/A | false | false |
| 11 | - | None But That! | $8,740 | - | 7 | - | $1,248 | $8,740 | 1 | N/A | true | false |
| 12 | 6 | Baby Mama | $3,769 | -92.9% | 1 | -17 | $3,769 | $84,046 | 2 | N/A | false | false |
| 13 | 10 | Nim's Island | $2,065 | -74.5% | 2 | -1 | $1,032 | $263,916 | 5 | N/A | false | false |
| 14 | 14 | Untraceable | $1,557 | +3.9% | 1 | - | $1,557 | $350,747 | 6 | N/A | false | false |
| 15 | 16 | Step Up 2: The Streets | $694 | -28.8% | 1 | - | $694 | $407,536 | 7 | N/A | false | false |
| 16 | 11 | Horton Hears a Who! | $566 | -81.6% | 1 | -1 | $566 | $443,154 | 13 | N/A | false | false |
| 17 | 17 | King of California | $402 | -54.2% | 1 | - | $402 | $43,850 | 4 | N/A | false | false |
