| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Indiana Jones and the Kingdom of the Crystal Skull | $98,102 | - | - | - | - | $101,923 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | What Happens in Vegas | $44,721 | -36.1% | - | - | - | $162,903 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | 3 | 21 | $11,465 | -18.9% | - | - | - | $144,238 | 4 | ACME | false | false |
| 4 | 2 | Speed Racer | $8,454 | -44.7% | - | - | - | $33,985 | 2 | Garsu Pasaulio Irasai | false | false |
| 5 | 5 | Iron Man | $8,004 | -27% | - | - | - | $137,837 | 4 | Universal Pictures International (UPI) | false | false |
| 6 | 4 | Fool's Gold | $7,978 | -32.1% | - | - | - | $79,828 | 3 | Garsu Pasaulio Irasai | false | false |
| 7 | 6 | The Eye | $6,307 | -5.9% | - | - | - | $42,427 | 3 | ACME | false | false |
| 8 | 7 | Horton Hears a Who! | $4,661 | +17.1% | - | - | - | $386,999 | 10 | Universal Pictures International (UPI) | false | false |
| 9 | - | Cassandra's Dream | $3,440 | - | - | - | - | $7,154 | 1 | ACME | true | false |
| 10 | 9 | The Game Plan | $2,011 | -31.8% | - | - | - | $181,547 | 8 | Universal Pictures International (UPI) | false | false |
| 11 | 8 | 99 Francs | $1,795 | -39.7% | - | - | - | $62,765 | 5 | ACME | false | false |
| 12 | 15 | My Blueberry Nights | $1,200 | +42.2% | - | - | - | $56,341 | 6 | ACME | false | false |
| 13 | 20 | Drillbit Taylor | $743 | +190.2% | - | - | - | $88,873 | 6 | Universal Pictures International (UPI) | false | false |
| 14 | 17 | Garfield: A Tail of Two Kitties | $728 | +102.8% | - | - | - | $364,989 | 96 | Universal Pictures International (UPI) | false | false |
| 15 | 11 | Sleuth | $558 | -61.1% | - | - | - | $18,696 | 4 | ACME | false | false |
| 16 | 19 | Ice Age: The Meltdown | $519 | +60.2% | - | - | - | $581,930 | 112 | Universal Pictures International (UPI) | false | false |
| 17 | - | The Fox and the Child | $466 | - | - | - | - | $758 | 2 | ACME | false | false |
| 18 | - | Street Kings | $371 | - | - | - | - | $28,522 | 7 | Universal Pictures International (UPI) | false | false |
| 19 | - | The Simpsons Movie | $361 | - | - | - | - | $890,890 | 44 | Universal Pictures International (UPI) | false | false |
| 20 | 14 | Shutter | $348 | -61% | - | - | - | $136,647 | 9 | Universal Pictures International (UPI) | false | false |
