| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Indiana Jones and the Kingdom of the Crystal Skull | $24,146,846 | - | 538 | - | $44,882 | $24,146,846 | 1 | Paramount Pictures International | true | false |
| 2 | 2 | What Happens in Vegas | $1,819,704 | -38.6% | 405 | - | $4,493 | $9,956,632 | 3 | 20th Century Fox International | false | false |
| 3 | 1 | Iron Man | $1,648,646 | -56.1% | 474 | -22 | $3,478 | $28,469,550 | 4 | Paramount Pictures International | false | false |
| 4 | 3 | Forgetting Sarah Marshall | $639,493 | -42.8% | 350 | -45 | $1,827 | $13,855,247 | 5 | Universal Pictures International (UPI) | false | false |
| 5 | 4 | Nim's Island | $580,973 | -34.1% | 390 | +4 | $1,489 | $4,900,360 | 4 | Universal Pictures International (UPI) | false | false |
| 6 | 5 | Speed Racer | $320,697 | -60.1% | 400 | -57 | $801 | $2,229,625 | 3 | Warner Bros. | false | false |
| 7 | 6 | Made of Honor | $238,107 | -57.3% | 214 | -110 | $1,112 | $4,342,116 | 4 | Sony Pictures Releasing | false | false |
| 8 | 7 | Doomsday | $156,995 | -68.3% | 208 | -51 | $754 | $1,865,193 | 3 | Universal Pictures International (UPI) | false | false |
| 9 | 9 | Caramel | $139,358 | -42% | 49 | +3 | $2,844 | $492,430 | 2 | Momentum Pictures | false | false |
| 10 | 8 | In Bruges | $118,850 | -54.6% | 84 | -66 | $1,414 | $9,179,244 | 12 | Universal Pictures International (UPI) | false | false |
| 11 | - | Cassandra's Dream | $93,522 | - | 50 | - | $1,870 | $93,522 | 1 | Optimum Releasing | true | false |
| 12 | 16 | Persepolis | $80,327 | -31.1% | 34 | -11 | $2,362 | $1,393,883 | 5 | Optimum Releasing | false | false |
| 13 | 14 | Shutter | $66,632 | -53.1% | 61 | -4 | $1,092 | $291,987 | 2 | 20th Century Fox International | false | false |
| 14 | 21 | The Spiderwick Chronicles | $59,626 | +67% | 208 | +91 | $286 | $20,795,143 | 10 | Paramount Pictures International | false | false |
| 15 | 17 | Jannat: In Search of Heaven... | $59,035 | -38.7% | 20 | -1 | $2,951 | $206,336 | 2 | - | false | false |
| 16 | 12 | Smart People | $58,788 | -65.9% | 49 | -24 | $1,199 | $315,395 | 2 | Icon Film Distribution | false | false |
| 17 | 15 | Happy-Go-Lucky | $55,676 | -59.1% | 42 | -52 | $1,325 | $2,930,367 | 6 | Momentum Pictures | false | false |
| 18 | 10 | 21 | $46,474 | -75.6% | 60 | -70 | $774 | $10,836,703 | 7 | Sony Pictures Releasing | false | false |
| 19 | 13 | The Eye | $42,453 | -74% | 56 | -108 | $758 | $3,618,797 | 5 | Lionsgate | false | false |
| 20 | 18 | Bhoothnath | $38,616 | -57.2% | 27 | -7 | $1,430 | $346,142 | 3 | Eros Worldwide | false | false |
| 21 | 11 | Charlie Bartlett | $36,944 | -80.6% | 83 | -119 | $445 | $341,523 | 2 | Verve Pictures | false | false |
| 22 | 25 | Horton Hears a Who! | $32,775 | +14% | 115 | +21 | $285 | $16,801,831 | 10 | 20th Century Fox International | false | false |
| 23 | - | Timber Falls | $24,208 | - | 22 | - | $1,100 | $24,208 | 1 | Scanbox Entertainment | true | false |
| 24 | 23 | Heartbeat Detector | $23,525 | -25.9% | 6 | - | $3,920 | $78,178 | 2 | Trinity Filmed Entertainment | false | false |
| 25 | 22 | Step Up 2: The Streets | $16,598 | -53.5% | 53 | -43 | $313 | $20,706,399 | 10 | Universal Pictures International (UPI) | false | false |
| 26 | 24 | Underdog | $15,978 | -44.9% | 42 | -19 | $380 | $2,823,136 | 17 | Walt Disney Pictures | false | false |
| 27 | 27 | Honeydripper | $13,924 | -45.5% | 12 | -5 | $1,160 | $117,527 | 3 | Axiom Films | false | false |
| 28 | 31 | XXY | $13,764 | -21.9% | 6 | -2 | $2,294 | $81,530 | 3 | Peccadillo Pictures | false | false |
| 29 | 19 | Outpost | $12,430 | -83.6% | 28 | -23 | $443 | $134,277 | 2 | Vertigo Films | false | false |
| 30 | 37 | The Diving Bell and the Butterfly | $12,385 | +15.3% | 12 | +6 | $1,032 | $1,704,283 | 16 | Pathé | false | false |
| 31 | 41 | Welcome to the Sticks | $11,102 | +46% | 45 | +42 | $246 | $172,483 | 8 | Pathé | false | false |
| 32 | 29 | The Oxford Murders | $10,069 | -46.5% | 8 | -12 | $1,258 | $441,880 | 5 | - | false | false |
| 33 | - | Shotgun Stories | $8,525 | - | 7 | - | $1,217 | $8,525 | 1 | Vertigo Films | true | false |
| 34 | 43 | Terror's Advocate | $7,571 | +29.4% | 3 | +1 | $2,523 | $19,234 | 2 | Artificial Eye | false | false |
| 35 | 32 | A Secret | $7,050 | -54.5% | 2 | - | $3,525 | $53,915 | 3 | Arrow Films | false | false |
| 36 | 34 | The Orphanage | $6,467 | -44.7% | 6 | -5 | $1,077 | $3,434,870 | 10 | Optimum Releasing | false | false |
| 37 | 28 | Fool's Gold | $6,191 | -69.4% | 15 | -26 | $412 | $4,732,249 | 6 | Warner Bros. | false | false |
| 38 | 20 | The Game Plan | $5,997 | -84.4% | 32 | -93 | $187 | $8,368,623 | 12 | Walt Disney Pictures | false | false |
| 39 | 33 | The Other Boleyn Girl | $5,458 | -64.3% | 5 | -5 | $1,091 | $9,278,821 | 12 | Universal Pictures International (UPI) | false | false |
| 40 | 39 | Some Came Running | $5,236 | -38.3% | 1 | -1 | $5,236 | $19,030 | 2 | British Film Institute (BFI) | false | false |
| 41 | - | Joy Division | $5,219 | - | 5 | - | $1,043 | $161,639 | 4 | N/A | false | false |
| 42 | 36 | Street Kings | $4,726 | -56.6% | 4 | -6 | $1,181 | $2,716,363 | 6 | 20th Century Fox International | false | false |
| 43 | 30 | Son of Rambow | $4,441 | -76.1% | 19 | -28 | $233 | $8,198,566 | 8 | Optimum Releasing | false | false |
| 44 | 47 | Leatherheads | $4,209 | -9.4% | 7 | -2 | $601 | $2,177,829 | 7 | Universal Pictures International (UPI) | false | false |
| 45 | 46 | My Brother is an Only Child | $3,857 | -19.2% | 4 | -1 | $964 | $625,308 | 8 | Revolver Entertainment | false | false |
| 46 | 45 | The Bank Job | $3,404 | -30.1% | 1 | -1 | $3,404 | $8,059,167 | 13 | Lionsgate | false | false |
| 47 | 38 | Shine a Light | $3,124 | -66.2% | 4 | -8 | $781 | $1,288,979 | 7 | 20th Century Fox International | false | false |
| 48 | 48 | Flashbacks of a Fool | $2,949 | -31.5% | 6 | +3 | $491 | $889,462 | 6 | Walt Disney Pictures | false | false |
| 49 | - | Dangerous Parking | $2,929 | - | 7 | - | $418 | $2,929 | 1 | Delanic Films | true | false |
| 50 | 35 | Tashan | $2,891 | -74.3% | 4 | -14 | $722 | $696,133 | 5 | Yash Raj Films | false | false |
| 51 | - | Garbage Warrior | $2,422 | - | 2 | - | $1,211 | $2,422 | 1 | ICA Films | true | false |
| 52 | 40 | Lars and the Real Girl | $2,389 | -71.7% | 7 | -3 | $341 | $837,095 | 10 | Verve Pictures | false | false |
| 53 | 55 | Funny Games | $2,240 | +22.3% | 6 | +1 | $373 | $404,285 | 8 | Tartan | false | false |
| 54 | 44 | Manufactured Landscapes | $2,006 | -61.6% | 2 | - | $1,003 | $34,066 | 3 | British Film Institute (BFI) | false | false |
| 55 | 51 | The Ugly Duckling and Me! | $1,878 | -28.5% | 9 | -2 | $208 | $825,145 | 47 | Eclipse Pictures | false | false |
| 56 | 50 | Love in the Time of Cholera | $1,874 | -29.7% | 3 | - | $624 | $718,441 | 10 | Momentum Pictures | false | false |
| 57 | 52 | Grindhouse | $944 | -53.7% | 3 | -2 | $314 | $183,596 | 9 | Momentum Pictures | false | false |
| 58 | - | Mister Lonely | $685 | - | 1 | - | $685 | $28,753 | 11 | Tartan | false | false |
| 59 | 26 | Where in the World Is Osama Bin Laden? | $637 | -97.7% | 3 | -30 | $212 | $127,793 | 3 | Optimum Releasing | false | false |
| 60 | 69 | Azur & Asmar: The Princes' Quest | $610 | +1,197.9% | 4 | +2 | $152 | $69,654 | 16 | Soda Pictures | false | false |
| 61 | 56 | The Last Mistress | $560 | -67.1% | 1 | -2 | $560 | $72,757 | 7 | Artificial Eye | false | false |
| 62 | 62 | P2 | $522 | -42% | 3 | -3 | $174 | $141,787 | 4 | Tartan | false | false |
| 63 | 70 | The 39 Steps 2008 Re-release | $424 | +987.2% | 2 | +1 | $212 | $48,227 | 7 | Park Circus | false | false |
| 64 | 75 | Redacted | $400 | +1,042.9% | 1 | - | $400 | $39,608 | 11 | Optimum Releasing | false | false |
| 65 | 58 | Vexille | $340 | -72.2% | 1 | - | $340 | $5,088 | 3 | Momentum Pictures | false | false |
| 66 | 53 | The Conformist 2008 Re-release | $291 | -85.2% | 1 | - | $291 | $218,862 | 13 | British Film Institute (BFI) | false | false |
| 67 | 49 | The Air I Breathe | $190 | -95.1% | 1 | -2 | $190 | $6,303 | 2 | Pathé | false | false |
| 68 | 59 | RFK Must Die: The Assassination of Bobby Kennedy | $168 | -85.3% | 1 | -1 | $168 | $1,945 | 2 | Soda Pictures | false | false |
| 69 | 74 | The Edge of Heaven | $146 | +274.4% | 1 | - | $146 | $279,032 | 14 | Artificial Eye | false | false |
| 70 | 60 | REC | $113 | -88.5% | 2 | -3 | $56 | $449,927 | 7 | - | false | false |
| 71 | 54 | You, the Living | $40 | -97.8% | 1 | -3 | $40 | $186,891 | 9 | Artificial Eye | false | false |
| 72 | 66 | Still Life | $40 | -81.4% | 1 | - | $40 | $73,982 | 17 | British Film Institute (BFI) | false | false |
| 73 | - | The Duchess of Langeais | $40 | - | 1 | - | $40 | $60,661 | 22 | Artificial Eye | false | false |
| 74 | - | My Blueberry Nights | $40 | - | 1 | - | $40 | $556,339 | 14 | Optimum Releasing | false | false |
| 75 | 63 | Never Back Down | $34 | -95.5% | 1 | -3 | $34 | $4,281,726 | 8 | Momentum Pictures | false | false |
