| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Indiana Jones and the Kingdom of the Crystal Skull | $1,624,805 | - | 103 | - | $15,774 | $1,624,805 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | What Happens in Vegas | $298,311 | -27% | 50 | - | $5,966 | $1,134,230 | 3 | 20th Century Fox International | false | false |
| 3 | 2 | Iron Man | $131,126 | -51.7% | 50 | -3 | $2,622 | $1,543,410 | 4 | Universal Pictures International (UPI) | false | false |
| 4 | 3 | Street Kings | $89,613 | -50.8% | 30 | - | $2,987 | $314,928 | 2 | 20th Century Fox International | false | false |
| 5 | 5 | Welcome to the Sticks | $63,763 | -33.1% | 35 | -16 | $1,821 | $9,681,103 | 13 | Alternative Films | false | false |
| 6 | 4 | 21 | $60,598 | -42.4% | 40 | -1 | $1,514 | $1,144,720 | 6 | Sony Pictures Releasing | false | false |
| 7 | - | Over Her Dead Body | $50,213 | - | 12 | - | $4,184 | $77,125 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 8 | 7 | Nim's Island | $41,431 | -47.4% | 50 | -5 | $828 | $404,912 | 4 | Belga Films | false | false |
| 9 | 8 | Horton Hears a Who! | $39,407 | -24.7% | 54 | - | $729 | $2,489,917 | 10 | 20th Century Fox International | false | false |
| 10 | 9 | The Mist | $37,015 | -28.1% | 20 | -1 | $1,850 | $428,025 | 5 | Benelux Film Distributors | false | false |
| 11 | 6 | Fool's Gold | $31,231 | -61.1% | 25 | - | $1,249 | $466,911 | 4 | Warner Bros. | false | false |
| 12 | 10 | Taken | $27,272 | -43.9% | 20 | -7 | $1,363 | $526,341 | 6 | Belga Films | false | false |
| 13 | 13 | Mongol: The Rise of Genghis Khan | $23,436 | -44.3% | 11 | - | $2,130 | $111,752 | 3 | Benelux Film Distributors | false | false |
| 14 | 12 | The Other Boleyn Girl | $20,394 | -51.8% | 23 | -11 | $886 | $781,394 | 7 | Universal Pictures International (UPI) | false | false |
| 15 | 11 | Cash | $20,210 | -53.2% | 15 | -4 | $1,347 | $347,635 | 5 | Belga Films | false | false |
| 16 | - | Lemon Tree | $19,518 | - | 11 | - | $1,774 | $28,372 | 1 | Cinéart | true | false |
| 17 | 14 | Doomsday | $14,263 | -60.2% | 14 | -1 | $1,018 | $90,007 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 18 | 20 | Hotel op stelten | $14,246 | -17.2% | 22 | -3 | $647 | $1,228,307 | 11 | Kinepolis Film Distribution (KFD) | false | false |
| 19 | 16 | The Spiderwick Chronicles | $14,119 | -45% | 22 | -6 | $641 | $1,551,498 | 10 | Universal Pictures International (UPI) | false | false |
| 20 | 27 | Moscow, Belgium | $12,997 | +12.6% | 7 | +2 | $1,856 | $1,662,627 | 17 | Kinepolis Film Distribution (KFD) | false | false |
| 21 | 21 | U2 3D | $10,434 | -30.4% | 8 | -1 | $1,304 | $372,706 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 22 | 15 | Definitely, Maybe | $10,195 | -64.5% | 11 | -12 | $926 | $107,353 | 3 | Universal Pictures International (UPI) | false | false |
| 23 | 18 | The Great Alibi | $9,396 | -49.9% | 6 | -2 | $1,566 | $59,120 | 3 | Les Films de l'Elysée | false | false |
| 24 | 22 | The Eye | $9,059 | -39.5% | 8 | -5 | $1,132 | $449,248 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 25 | 17 | REC | $8,912 | -56.6% | 8 | -4 | $1,114 | $115,485 | 4 | Paradiso Entertainment | false | false |
| 26 | 24 | Winx Club: The Secret of the Lost Kingdom | $8,777 | -35.5% | 5 | -2 | $1,755 | $577,227 | 9 | Independent Films | false | false |
| 27 | 19 | 120 | $8,692 | -49.5% | 3 | +1 | $2,897 | $41,854 | 3 | N/A | false | false |
| 28 | 31 | Fly Me to the Moon 3D | $7,771 | -21% | 5 | -1 | $1,554 | $1,079,815 | 17 | Kinepolis Film Distribution (KFD) | false | false |
| 29 | 26 | I've Loved You So Long | $7,533 | -40.7% | 14 | -3 | $538 | $493,887 | 10 | Benelux Film Distributors | false | false |
| 30 | 29 | The Band's Visit | $6,954 | -38.4% | 8 | -1 | $869 | $100,295 | 5 | Paradiso Entertainment | false | false |
| 31 | - | Days and Clouds | $6,501 | - | 6 | - | $1,083 | $7,861 | 1 | ABC Distribution | true | false |
| 32 | 30 | Untraceable | $6,185 | -40.8% | 5 | -2 | $1,237 | $1,041,618 | 12 | Kinepolis Film Distribution (KFD) | false | false |
| 33 | 33 | Julia | $5,934 | -33.7% | 8 | - | $741 | $28,003 | 3 | Cinéart | false | false |
| 34 | - | Delirious | $5,729 | - | 2 | - | $2,864 | $5,729 | 1 | N/A | true | false |
| 35 | 38 | Step Up 2: The Streets | $4,974 | -36.7% | 7 | -8 | $710 | $3,409,040 | 13 | Benelux Film Distributors | false | false |
| 36 | 43 | No Country for Old Men | $4,961 | -1% | 7 | -2 | $708 | $1,843,327 | 18 | Universal Pictures International (UPI) | false | false |
| 37 | 35 | In Memory of Me | $4,936 | -44.7% | 5 | -1 | $987 | $18,357 | 2 | Cinéart | false | false |
| 38 | 34 | Dragon Hunters | $4,834 | -46% | 12 | -5 | $402 | $377,213 | 9 | Belga Films | false | false |
| 39 | 41 | The Ruins | $4,724 | -37.1% | 6 | -3 | $787 | $200,223 | 6 | Universal Pictures International (UPI) | false | false |
| 40 | 28 | Disco | $4,622 | -59.7% | 9 | -7 | $513 | $812,769 | 8 | Universal Pictures International (UPI) | false | false |
| 41 | 39 | There Will Be Blood | $4,423 | -43.5% | 8 | -2 | $552 | $657,829 | 14 | Walt Disney Pictures | false | false |
| 42 | 23 | Tu peux garder un secret? | $4,358 | -69.5% | 3 | -2 | $1,452 | $23,009 | 2 | Les Films de l'Elysée | false | false |
| 43 | 42 | Linkeroever | $4,229 | -26.7% | 3 | - | $1,409 | $361,579 | 9 | Kinepolis Film Distribution (KFD) | false | false |
| 44 | 25 | Love in the Time of Cholera | $3,739 | -71.2% | 11 | -5 | $339 | $106,811 | 4 | Cinéart | false | false |
| 45 | 47 | Never Back Down | $2,651 | -4.5% | 4 | -1 | $662 | $87,025 | 5 | Paradiso Entertainment | false | false |
| 46 | 45 | Vantage Point | $2,490 | -46.1% | 2 | -2 | $1,245 | $923,107 | 9 | Sony Pictures Releasing | false | false |
| 47 | 46 | Les randonneurs à Saint-Tropez | $1,814 | -54.6% | 4 | -1 | $453 | $312,806 | 7 | Belga Films | false | false |
| 48 | 53 | Mr. Magorium's Wonder Emporium | $1,597 | +56.4% | 1 | - | $1,597 | $340,793 | 22 | Benelux Film Distributors | false | false |
| 49 | 44 | The Kite Runner | $1,439 | -69.2% | 8 | -3 | $179 | $811,461 | 15 | Universal Pictures International (UPI) | false | false |
| 50 | 48 | The Game Plan | $1,157 | -53.3% | 6 | -6 | $192 | $463,265 | 9 | Walt Disney Pictures | false | false |
| 51 | 56 | Redacted | $857 | +984.8% | 2 | - | $428 | $17,223 | 13 | Paradiso Entertainment | false | false |
| 52 | - | Munyurangabo | $658 | - | 1 | - | $658 | $658 | 1 | N/A | true | false |
| 53 | 32 | Resurrecting the Champ | $467 | -95.1% | 4 | -4 | $116 | $13,221 | 2 | Belga Films | false | false |
| 54 | 52 | Once | $306 | -75.6% | 3 | - | $102 | $41,804 | 12 | Paradiso Entertainment | false | false |
| 55 | 49 | The Home Song Stories | $289 | -87.8% | 1 | -2 | $289 | $3,548 | 2 | Paradiso Entertainment | false | false |
| 56 | 55 | Lou Reed's Berlin | $116 | -59.4% | 1 | - | $116 | $2,654 | 4 | Paradiso Entertainment | false | false |
