| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Speed Racer | $584,699 | - | 86 | - | $6,798 | $584,696 | 1 | Warner Bros. | true | false |
| 2 | 1 | Iron Man | $278,499 | -45.8% | 78 | +3 | $3,570 | $983,813 | 2 | United International Pictures | false | false |
| 3 | 2 | The Nest | $119,986 | -36.9% | 38 | -1 | $3,157 | $652,821 | 3 | Distribution Company | false | false |
| 4 | - | The Oxford Murders | $115,071 | - | 22 | - | $5,230 | $115,071 | 1 | Pachamama Cine | true | false |
| 5 | 3 | Death at a Funeral | $114,075 | -17.2% | 33 | +1 | $3,456 | $1,376,345 | 10 | - | false | false |
| 6 | 4 | 21 | $77,578 | -26.6% | 37 | -20 | $2,096 | $546,556 | 4 | Sony Pictures Releasing | false | false |
| 7 | - | Lamb of God | $50,369 | - | 13 | - | $3,874 | $50,369 | 1 | Alfa Films | true | false |
| 8 | 5 | Shutter | $47,432 | -21.2% | 33 | +6 | $1,437 | $306,837 | 4 | 20th Century Fox International | false | false |
| 9 | 9 | Untraceable | $33,441 | -5.6% | 29 | - | $1,153 | $148,510 | 3 | Sony Pictures Releasing | false | false |
| 10 | 10 | Conversations with My Gardener | $23,575 | -30.8% | 13 | -1 | $1,813 | $121,225 | 3 | Alfa Films | false | false |
| 11 | 6 | The Savages | $23,184 | -52.2% | 16 | - | $1,449 | $81,703 | 2 | 20th Century Fox International | false | false |
| 12 | 7 | Street Kings | $16,870 | -61.7% | 37 | +6 | $455 | $166,486 | 3 | 20th Century Fox International | false | false |
| 13 | 14 | The Orphanage | $15,484 | -38% | 33 | +11 | $469 | $699,190 | 9 | CDI Films | false | false |
| 14 | 21 | In the Valley of Elah | $14,817 | +15.4% | 13 | - | $1,139 | $266,264 | 6 | Alfa Films | false | false |
| 15 | 11 | Horton Hears a Who! | $13,494 | -58.3% | 53 | -1 | $254 | $1,169,919 | 9 | 20th Century Fox International | false | false |
| 16 | 12 | 10,000 BC | $12,168 | -61.5% | 41 | -27 | $296 | $2,178,736 | 10 | Warner Bros. | false | false |
| 17 | 8 | We Own the Night | $11,698 | -67.3% | 14 | -3 | $835 | $55,496 | 2 | CDI Films | false | false |
| 18 | 17 | Evening | $10,130 | -45% | 15 | -6 | $675 | $169,972 | 5 | Impacto Cine | false | false |
| 19 | 18 | P.S. I Love You | $9,446 | -36.1% | 15 | -3 | $629 | $428,560 | 11 | Alfa Films | false | false |
| 20 | 20 | The Game Plan | $8,070 | -40.1% | 51 | +2 | $158 | $1,441,059 | 13 | Walt Disney Pictures | false | false |
| 21 | 15 | Jumper | $7,758 | -68.2% | 62 | +17 | $125 | $559,104 | 6 | 20th Century Fox International | false | false |
| 22 | 13 | Lust, Caution | $7,299 | -75.6% | 18 | - | $405 | $45,570 | 2 | Distribution Company | false | false |
| 23 | 16 | The Spiderwick Chronicles | $7,248 | -68.9% | 31 | -12 | $233 | $652,087 | 8 | United International Pictures | false | false |
| 24 | - | Silk | $7,059 | - | 5 | - | $1,411 | $7,059 | 1 | Distribution Company | true | false |
| 25 | 24 | Persepolis | $6,583 | -28.3% | 3 | - | $2,194 | $30,361 | 3 | Sony Pictures Releasing | false | false |
| 26 | 22 | Twice Upon a Time | $6,012 | -46.7% | 9 | -5 | $668 | $103,514 | 4 | Pachamama Cine | false | false |
| 27 | 19 | Two Days in Paris | $4,060 | -70.7% | 5 | -10 | $812 | $328,873 | 7 | Impacto Cine | false | false |
| 28 | 23 | No Country for Old Men | $3,967 | -57.4% | 20 | -10 | $198 | $951,405 | 10 | Walt Disney Pictures | false | false |
| 29 | 26 | The Hunting Party | $2,672 | -65.5% | 11 | -6 | $242 | $301,949 | 8 | Distribution Company | false | false |
| 30 | 28 | Caramel | $2,608 | -58.8% | 7 | -2 | $372 | $208,046 | 7 | Alfa Films | false | false |
| 31 | 25 | The Bucket List | $2,480 | -69.7% | 12 | -9 | $206 | $1,932,541 | 14 | Warner Bros. | false | false |
| 32 | 41 | Rain | $1,706 | +31.7% | 16 | -1 | $106 | $158,239 | 8 | Walt Disney Pictures | false | false |
| 33 | 33 | Mr. Woodcock | $1,652 | -55.8% | 5 | -4 | $330 | $95,568 | 6 | Distribution Company | false | false |
| 34 | 29 | 1408 | $1,490 | -73.4% | 3 | -6 | $496 | $262,789 | 16 | United International Pictures | false | false |
| 35 | 27 | Elizabeth: The Golden Age | $1,271 | -80.9% | 2 | -5 | $635 | $101,084 | 9 | United International Pictures | false | false |
| 36 | 35 | Diary of the Dead | $1,216 | -48.2% | 5 | -7 | $243 | $286,854 | 8 | Pachamama Cine | false | false |
| 37 | 50 | The Eye | $977 | +34.9% | 2 | -1 | $488 | $228,386 | 11 | United International Pictures | false | false |
| 38 | 30 | King of California | $865 | -80.6% | 5 | -5 | $173 | $63,440 | 5 | Distribution Company | false | false |
| 39 | 44 | La orilla que se abisma | $864 | -10.9% | 2 | - | $432 | $2,153 | 2 | Primer Plano Film Group | false | false |
| 40 | 56 | Vantage Point | $824 | +78.4% | 3 | +2 | $274 | $387,184 | 11 | Sony Pictures Releasing | false | false |
| 41 | 51 | Rancho aparte | $685 | -2.3% | 2 | +1 | $342 | $135,910 | 7 | - | false | false |
| 42 | 45 | The Ugly Duckling and Me! | $664 | -31.1% | 9 | -4 | $73 | $72,536 | 8 | - | false | false |
| 43 | 32 | The Nanny Diaries | $580 | -85.9% | 4 | -6 | $145 | $70,127 | 4 | Alfa Films | false | false |
| 44 | 38 | Shine a Light | $545 | -65.9% | 6 | -5 | $90 | $95,204 | 5 | Distribution Company | false | false |
| 45 | 37 | The Darjeeling Limited | $490 | -74.8% | 11 | -1 | $44 | $118,402 | 8 | 20th Century Fox International | false | false |
| 46 | 46 | Construcción de una ciudad | $388 | -57.8% | 1 | -1 | $388 | $1,483 | 2 | N/A | false | false |
| 47 | 36 | Winter Visitor | $313 | -86.6% | 5 | -8 | $62 | $33,982 | 6 | Primer Plano Film Group | false | false |
| 48 | - | U2 3D | $292 | - | 1 | - | $292 | $142,305 | 7 | IMAX | false | false |
| 49 | 40 | The Water Horse | $279 | -81.1% | 4 | -4 | $69 | $590,328 | 14 | Sony Pictures Releasing | false | false |
| 50 | 49 | Rambo | $273 | -64.7% | 2 | - | $136 | $324,433 | 12 | CDI Films | false | false |
| 51 | 57 | Hannibal Rising | $256 | -30.4% | 2 | +1 | $128 | $88,958 | 12 | United International Pictures | false | false |
| 52 | 47 | There Will Be Blood | $250 | -70% | 7 | -3 | $35 | $501,922 | 12 | Walt Disney Pictures | false | false |
| 53 | 62 | The Bothersome Man | $247 | -12.4% | 2 | - | $123 | $7,986 | 5 | IFA | false | false |
| 54 | 31 | Elite Squad | $240 | -94.5% | 7 | -6 | $34 | $99,815 | 6 | United International Pictures | false | false |
| 55 | 42 | I Could Never Be Your Woman | $223 | -78.5% | 1 | - | $223 | $302,572 | 19 | CDI Films | false | false |
| 56 | 48 | Juno | $205 | -74.6% | 3 | - | $68 | $462,163 | 13 | Alfa Films | false | false |
| 57 | 53 | 3:10 to Yuma | $182 | -69.8% | 1 | -4 | $182 | $276,073 | 11 | Distribution Company | false | false |
| 58 | 63 | Bridge to Terabithia | $161 | -23.7% | 1 | - | $161 | $101,169 | 18 | United International Pictures | false | false |
| 59 | 55 | Enchanted | $146 | -74.8% | 3 | -4 | $48 | $2,792,561 | 19 | Walt Disney Pictures | false | false |
| 60 | 54 | Alvin and the Chipmunks | $144 | -75.4% | 3 | -1 | $48 | $795,963 | 19 | 20th Century Fox International | false | false |
| 61 | 61 | Atonement | $101 | -64.9% | 1 | -3 | $101 | $503,315 | 14 | United International Pictures | false | false |
| 62 | 65 | D-Graduated | $94 | -53.9% | 1 | - | $94 | $14,872 | 7 | Distribution Company | false | false |
| 63 | 58 | The Golden Compass | $87 | -75.1% | 2 | - | $43 | $1,387,150 | 22 | Distribution Company | false | false |
| 64 | 66 | The Dog Pound | $74 | -55.2% | 1 | -3 | $74 | $4,825 | 4 | Primer Plano Film Group | false | false |
| 65 | - | Martín Fierro, el ave solitaria | $59 | - | 1 | - | $59 | $154,324 | 99 | Cinemagroup | false | false |
| 66 | 34 | Offside | $45 | -98.1% | 1 | -2 | $45 | $2,934 | 2 | 791 Cine | false | false |
| 67 | 70 | National Treasure: Book of Secrets | $40 | -24.5% | 3 | +1 | $13 | $1,660,722 | 17 | Walt Disney Pictures | false | false |
| 68 | - | Possible Lives | $40 | - | 1 | - | $40 | $19,236 | 14 | Primer Plano Film Group | false | false |
| 69 | 60 | Evita, otra mirada | $37 | -87.3% | 1 | - | $37 | $477 | 2 | N/A | false | false |
| 70 | 72 | Bee Movie | $27 | -41.3% | 1 | - | $27 | $1,469,065 | 23 | United International Pictures | false | false |
| 71 | 71 | Underdog | $23 | -50% | 1 | -1 | $23 | $848,803 | 32 | Walt Disney Pictures | false | false |
| 72 | 59 | Explosive Brigade: Pirate Mission | $14 | -95.6% | 3 | -1 | $4 | $763,965 | 15 | Argentina Sono Film S.A.C.I. | false | false |
