| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Iron Man | $10,772,921 | - | 500 | - | $21,545 | $10,772,921 | 1 | Paramount Pictures International | true | false |
| 2 | 1 | Forgetting Sarah Marshall | $2,619,545 | -38.5% | 391 | -2 | $6,699 | $8,634,185 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | - | Nim's Island | $1,616,830 | - | 393 | - | $4,114 | $1,616,830 | 1 | Universal Pictures International (UPI) | true | false |
| 4 | - | Made of Honor | $1,477,648 | - | 348 | - | $4,246 | $1,477,648 | 1 | Sony Pictures Releasing | true | false |
| 5 | 2 | The Eye | $722,054 | -48.4% | 355 | -15 | $2,033 | $2,705,086 | 2 | Lionsgate | false | false |
| 6 | 3 | 21 | $629,446 | -42.1% | 301 | -47 | $2,091 | $9,903,613 | 4 | Sony Pictures Releasing | false | false |
| 7 | 5 | In Bruges | $585,397 | -27.7% | 233 | -26 | $2,512 | $8,013,438 | 9 | Universal Pictures International (UPI) | false | false |
| 8 | 4 | Fool's Gold | $372,996 | -60.6% | 304 | -94 | $1,226 | $4,418,640 | 3 | Warner Bros. | false | false |
| 9 | 10 | Happy-Go-Lucky | $351,646 | -25.6% | 109 | -5 | $3,226 | $2,138,949 | 3 | Momentum Pictures | false | false |
| 10 | 14 | Persepolis | $249,180 | -21% | 47 | +3 | $5,301 | $747,159 | 2 | Optimum Releasing | false | false |
| 11 | 6 | Son of Rambow | $207,575 | -62.5% | 252 | -53 | $823 | $7,986,568 | 5 | Optimum Releasing | false | false |
| 12 | 9 | The Spiderwick Chronicles | $194,256 | -59% | 351 | -84 | $553 | $20,492,841 | 7 | Paramount Pictures International | false | false |
| 13 | 11 | Step Up 2: The Streets | $194,071 | -58.8% | 273 | -63 | $710 | $20,444,232 | 7 | Universal Pictures International (UPI) | false | false |
| 14 | 7 | Deception | $162,841 | -68% | 213 | -78 | $764 | $932,338 | 2 | Entertainment Film Distributors | false | false |
| 15 | - | Kuruvi | $152,431 | - | 13 | - | $11,725 | $152,431 | 1 | Ayngaran International | true | false |
| 16 | 8 | Street Kings | $128,425 | -74.2% | 135 | -176 | $951 | $2,575,987 | 3 | 20th Century Fox International | false | false |
| 17 | 15 | Horton Hears a Who! | $113,724 | -56.9% | 255 | -111 | $445 | $16,602,584 | 7 | 20th Century Fox International | false | false |
| 18 | 13 | Tashan | $110,607 | -69.4% | 43 | -3 | $2,572 | $586,608 | 2 | Yash Raj Films | false | false |
| 19 | 17 | The Oxford Murders | $78,731 | -50.7% | 51 | -11 | $1,543 | $332,080 | 2 | - | false | false |
| 20 | - | P2 | $72,198 | - | 124 | - | $582 | $72,198 | 1 | Tartan | true | false |
| 21 | 16 | 27 Dresses | $70,580 | -70.8% | 79 | -125 | $893 | $13,243,154 | 6 | 20th Century Fox International | false | false |
| 22 | 21 | Shine a Light | $42,360 | -22.9% | 8 | -8 | $5,295 | $1,218,092 | 4 | 20th Century Fox International | false | false |
| 23 | 19 | Underdog | $41,189 | -43.6% | 59 | +2 | $698 | $2,727,711 | 14 | Walt Disney Pictures | false | false |
| 24 | - | Mr. White Mr. Black | $29,852 | - | 11 | - | $2,713 | $29,852 | 1 | Eros Worldwide | true | false |
| 25 | 12 | A Deal Is a Deal | $27,071 | -92.8% | 109 | -271 | $248 | $596,923 | 2 | Worldwide Bonus Entertainment | false | false |
| 26 | 20 | The Orphanage | $21,396 | -62.1% | 17 | -18 | $1,258 | $3,370,371 | 7 | Optimum Releasing | false | false |
| 27 | 23 | The Game Plan | $20,763 | -59.1% | 66 | -58 | $314 | $8,278,457 | 9 | Walt Disney Pictures | false | false |
| 28 | 55 | U2 3D | $19,939 | +482.8% | 3 | +1 | $6,646 | $1,385,892 | 11 | Revolver Entertainment | false | false |
| 29 | 26 | U Me Aur Hum | $13,929 | -65.6% | 20 | -8 | $696 | $811,670 | 4 | Eros Worldwide | false | false |
| 30 | 18 | Flashbacks of a Fool | $11,585 | -85% | 15 | -125 | $772 | $863,347 | 3 | Walt Disney Pictures | false | false |
| 31 | 32 | My Brother is an Only Child | $11,380 | -55% | 8 | -8 | $1,422 | $584,650 | 5 | Revolver Entertainment | false | false |
| 32 | 38 | Welcome to the Sticks | $9,927 | -28.3% | 5 | +1 | $1,985 | $134,530 | 5 | Pathé | false | false |
| 33 | 27 | Leatherheads | $9,797 | -75.7% | 12 | -51 | $816 | $2,048,673 | 4 | Universal Pictures International (UPI) | false | false |
| 34 | 57 | Juno | $9,468 | +212.5% | 8 | +6 | $1,183 | $19,195,547 | 13 | 20th Century Fox International | false | false |
| 35 | 36 | The Other Boleyn Girl | $8,662 | -45% | 6 | -7 | $1,443 | $9,183,917 | 9 | Universal Pictures International (UPI) | false | false |
| 36 | 34 | There Will Be Blood | $8,585 | -49.5% | 5 | -12 | $1,717 | $9,264,013 | 13 | Walt Disney Pictures | false | false |
| 37 | 44 | 10,000 BC | $8,252 | +6.2% | 18 | -2 | $458 | $11,349,484 | 8 | Warner Bros. | false | false |
| 38 | 28 | Drillbit Taylor | $8,110 | -77% | 24 | -45 | $337 | $4,421,782 | 6 | Paramount Pictures International | false | false |
| 39 | 43 | Private Property | $6,460 | -20% | 3 | +1 | $2,153 | $38,522 | 3 | Soda Pictures | false | false |
| 40 | 53 | The Diving Bell and the Butterfly | $6,235 | +51.5% | 9 | +4 | $692 | $1,622,689 | 13 | Pathé | false | false |
| 41 | 47 | The Bank Job | $5,973 | +4.3% | 6 | +3 | $995 | $8,001,676 | 10 | Lionsgate | false | false |
| 42 | 33 | Lars and the Real Girl | $4,950 | -74.9% | 8 | -5 | $618 | $806,170 | 7 | Verve Pictures | false | false |
| 43 | 30 | One Missed Call | $4,678 | -83.5% | 7 | -30 | $668 | $2,339,087 | 5 | Warner Bros. | false | false |
| 44 | 39 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $4,283 | -59.5% | 8 | -3 | $535 | $1,559,257 | 8 | Walt Disney Pictures | false | false |
| 45 | 22 | Never Back Down | $4,035 | -92.3% | 19 | -76 | $212 | $4,260,095 | 5 | Momentum Pictures | false | false |
| 46 | 61 | You, the Living | $3,806 | +54.2% | 4 | +3 | $951 | $176,594 | 6 | Artificial Eye | false | false |
| 47 | 42 | Grindhouse | $3,804 | -56.5% | 6 | -5 | $634 | $164,638 | 6 | Momentum Pictures | false | false |
| 48 | 40 | Love in the Time of Cholera | $3,521 | -65% | 3 | -10 | $1,173 | $698,744 | 7 | Momentum Pictures | false | false |
| 49 | 31 | The Water Horse | $3,475 | -87.2% | 21 | -56 | $165 | $9,501,096 | 13 | Sony Pictures Releasing | false | false |
| 50 | 37 | REC | $3,302 | -76.3% | 9 | -9 | $366 | $443,491 | 4 | - | false | false |
| 51 | 46 | The Last Mistress | $3,008 | -47.8% | 1 | -1 | $3,008 | $56,769 | 4 | Artificial Eye | false | false |
| 52 | 64 | Flight of the Red Balloon | $2,478 | +118.9% | 4 | +2 | $619 | $86,377 | 8 | Park Circus | false | false |
| 53 | 54 | Vantage Point | $2,456 | -36.6% | 4 | -3 | $614 | $11,552,655 | 9 | Sony Pictures Releasing | false | false |
| 54 | - | Tovarisch, I Am Not Dead | $2,397 | - | 1 | - | $2,397 | $2,397 | 1 | N/A | true | false |
| 55 | 78 | Funny Games | $1,681 | +4,102.5% | 3 | +2 | $560 | $390,022 | 5 | Tartan | false | false |
| 56 | 50 | Death Note 2008 Re-release | $1,622 | -65.8% | 1 | - | $1,622 | $7,092 | 2 | - | false | false |
| 57 | 35 | Stop-Loss | $1,583 | -90.3% | 3 | -21 | $527 | $30,982 | 2 | Paramount Pictures International | false | false |
| 58 | 48 | The 39 Steps 2008 Re-release | $1,473 | -74.1% | 1 | - | $1,473 | $44,524 | 4 | Park Circus | false | false |
| 59 | 29 | The Ugly Duckling and Me! | $1,311 | -95.4% | 9 | -84 | $145 | $815,407 | 44 | Eclipse Pictures | false | false |
| 60 | 74 | Azur & Asmar: The Princes' Quest | $1,023 | +430.1% | 5 | +3 | $204 | $68,393 | 13 | Soda Pictures | false | false |
| 61 | 71 | Still Life | $887 | +69.3% | 1 | - | $887 | $71,153 | 14 | British Film Institute (BFI) | false | false |
| 62 | - | Beaufort | $735 | - | 3 | - | $245 | $24,374 | 6 | Trinity Filmed Entertainment | false | false |
| 63 | 67 | Mister Lonely | $719 | -26.9% | 1 | -1 | $719 | $26,976 | 8 | Tartan | false | false |
| 64 | 80 | The Edge of Heaven | $445 | +1,012.5% | 2 | +1 | $222 | $276,698 | 11 | Artificial Eye | false | false |
| 65 | 63 | The Conformist 2008 Re-release | $394 | -73.7% | 1 | -2 | $394 | $209,801 | 10 | British Film Institute (BFI) | false | false |
| 66 | 77 | In the Valley of Elah | $317 | +692.5% | 1 | - | $317 | $1,734,605 | 15 | Optimum Releasing | false | false |
| 67 | 81 | Away from Her | $187 | +1,068.8% | 1 | - | $187 | $303,412 | 12 | Metrodome Distribution | false | false |
| 68 | 69 | Redacted | $39 | -94% | 1 | -2 | $39 | $38,790 | 8 | Optimum Releasing | false | false |
| 69 | 68 | Under the Bombs | $39 | -95.2% | 1 | - | $39 | $30,867 | 7 | Artificial Eye | false | false |
| 70 | 65 | I'm a Cyborg, But That's OK | $39 | -96.4% | 1 | -1 | $39 | $20,369 | 5 | Tartan | false | false |
| 71 | 56 | My Blueberry Nights | $39 | -98.7% | 1 | -3 | $39 | $553,528 | 11 | Optimum Releasing | false | false |
