| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | 27 Dresses | $3,495,308 | - | 428 | - | $8,166 | $3,495,308 | 1 | 20th Century Fox International | true | false |
| 2 | 3 | Step Up 2: The Streets | $2,737,759 | -41.5% | 351 | +4 | $7,799 | $11,326,179 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | 2 | The Spiderwick Chronicles | $2,604,124 | -48.6% | 481 | - | $5,413 | $11,478,718 | 2 | Paramount Pictures International | false | false |
| 4 | 1 | Horton Hears a Who! | $1,868,830 | -68% | 504 | +3 | $3,707 | $10,719,787 | 2 | 20th Century Fox International | false | false |
| 5 | - | Drillbit Taylor | $1,445,141 | - | 302 | - | $4,785 | $1,445,141 | 1 | Paramount Pictures International | true | false |
| 6 | 4 | Meet the Spartans | $1,039,260 | -54.1% | 355 | +5 | $2,927 | $5,048,732 | 2 | 20th Century Fox International | false | false |
| 7 | 5 | 10,000 BC | $950,080 | -53.7% | 394 | -36 | $2,411 | $10,072,698 | 3 | Warner Bros. | false | false |
| 8 | 6 | Vantage Point | $792,506 | -46.1% | 288 | -35 | $2,751 | $10,408,855 | 4 | Sony Pictures Releasing | false | false |
| 9 | 7 | The Game Plan | $620,816 | -44.3% | 351 | -17 | $1,768 | $7,029,994 | 4 | Walt Disney Pictures | false | false |
| 10 | 10 | The Orphanage | $560,792 | -14.1% | 103 | +29 | $5,444 | $1,756,656 | 2 | Optimum Releasing | false | false |
| 11 | 8 | The Other Boleyn Girl | $491,474 | -48.8% | 262 | -52 | $1,875 | $8,172,441 | 4 | Universal Pictures International (UPI) | false | false |
| 12 | 12 | In Bruges | $345,557 | -22.7% | 64 | -4 | $5,399 | $3,490,989 | 4 | Universal Pictures International (UPI) | false | false |
| 13 | 11 | The Bank Job | $312,812 | -43.7% | 143 | -54 | $2,187 | $7,579,334 | 5 | Lionsgate | false | false |
| 14 | 9 | Race | $243,192 | -66.6% | 45 | -1 | $5,404 | $1,370,718 | 2 | UTV Motion Pictures | false | false |
| 15 | 13 | There Will Be Blood | $211,565 | -24.8% | 112 | -1 | $1,888 | $8,758,666 | 8 | Walt Disney Pictures | false | false |
| 16 | 19 | Lars and the Real Girl | $128,546 | -17.7% | 26 | +1 | $4,944 | $424,941 | 2 | Verve Pictures | false | false |
| 17 | 14 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $124,899 | -44.4% | 64 | -1 | $1,951 | $1,244,048 | 3 | Walt Disney Pictures | false | false |
| 18 | 23 | Alvin and the Chipmunks | $124,349 | +11.7% | 171 | +18 | $727 | $23,145,882 | 15 | 20th Century Fox International | false | false |
| 19 | 16 | Juno | $103,870 | -47% | 66 | -25 | $1,573 | $19,211,290 | 8 | 20th Century Fox International | false | false |
| 20 | 18 | Love in the Time of Cholera | $97,791 | -46.3% | 63 | -10 | $1,552 | $426,323 | 2 | Momentum Pictures | false | false |
| 21 | - | First Sunday | $81,168 | - | 68 | - | $1,193 | $81,168 | 1 | Sony Pictures Releasing | true | false |
| 22 | 24 | No Country for Old Men | $76,485 | -25.8% | 32 | -9 | $2,390 | $14,057,246 | 11 | Paramount Pictures International | false | false |
| 23 | - | One Two Three | $76,473 | - | 13 | - | $5,882 | $76,473 | 1 | Eros Worldwide | true | false |
| 24 | 20 | The Water Horse | $59,611 | -51.6% | 157 | -52 | $379 | $9,374,289 | 8 | Sony Pictures Releasing | false | false |
| 25 | 17 | The Accidental Husband | $50,690 | -72.7% | 62 | -66 | $817 | $4,963,581 | 5 | Momentum Pictures | false | false |
| 26 | 25 | Untraceable | $46,052 | -52.6% | 30 | -45 | $1,535 | $3,442,321 | 5 | Universal Pictures International (UPI) | false | false |
| 27 | 21 | Be Kind Rewind | $43,196 | -64.2% | 63 | -59 | $685 | $7,618,843 | 6 | Pathé | false | false |
| 28 | - | Grindhouse | $42,743 | - | 45 | - | $949 | $42,743 | 1 | Momentum Pictures | true | false |
| 29 | - | You, the Living | $39,015 | - | 6 | - | $6,502 | $39,015 | 1 | Artificial Eye | true | false |
| 30 | 15 | The Cottage | $36,913 | -81.9% | 56 | -157 | $659 | $1,375,984 | 3 | Pathé | false | false |
| 31 | 22 | Jumper | $35,119 | -70.5% | 39 | -47 | $900 | $17,190,891 | 7 | 20th Century Fox International | false | false |
| 32 | - | The Hottie & the Nottie | $34,231 | - | 28 | - | $1,222 | $34,231 | 1 | Pathé | true | false |
| 33 | 29 | U2 3D | $32,903 | -13.7% | 7 | -2 | $4,700 | $1,289,490 | 6 | Revolver Entertainment | false | false |
| 34 | 36 | The Diving Bell and the Butterfly | $26,343 | +90.3% | 11 | +5 | $2,394 | $1,442,774 | 8 | Pathé | false | false |
| 35 | 37 | The Kite Runner | $24,708 | +82.9% | 11 | +7 | $2,246 | $7,180,351 | 14 | Paramount Pictures International | false | false |
| 36 | 28 | National Treasure: Book of Secrets | $24,219 | -55.4% | 28 | -27 | $864 | $17,626,166 | 8 | Walt Disney Pictures | false | false |
| 37 | 26 | The Golden Compass | $16,869 | -80.2% | 70 | -144 | $240 | $52,171,844 | 17 | Entertainment Film Distributors | false | false |
| 38 | 27 | Semi-Pro | $16,828 | -73.2% | 25 | -37 | $673 | $4,178,812 | 5 | Entertainment Film Distributors | false | false |
| 39 | 31 | The Ugly Duckling and Me! | $16,367 | -22.2% | 74 | -9 | $221 | $740,363 | 39 | Eclipse Pictures | false | false |
| 40 | 35 | Penelope | $11,440 | -31.4% | 40 | -24 | $286 | $6,412,293 | 9 | Momentum Pictures | false | false |
| 41 | - | Beaufort | $11,248 | - | 2 | - | $5,624 | $11,248 | 1 | Trinity Filmed Entertainment | true | false |
| 42 | 41 | Water Lilies | $11,220 | +3.3% | 7 | +3 | $1,602 | $71,041 | 3 | Slingshot Studios | false | false |
| 43 | 39 | Sweeney Todd: The Demon Barber of Fleet Street | $8,377 | -24.9% | 20 | +16 | $418 | $21,785,480 | 10 | Warner Bros. | false | false |
| 44 | 34 | My Blueberry Nights | $7,430 | -56.2% | 7 | -5 | $1,061 | $537,145 | 6 | Optimum Releasing | false | false |
| 45 | 44 | The Conformist 2008 Re-release | $6,859 | -9.1% | 5 | +3 | $1,371 | $172,429 | 5 | British Film Institute (BFI) | false | false |
| 46 | 46 | La Vie En Rose | $6,325 | +13.1% | 4 | +1 | $1,581 | $3,360,495 | 41 | Icon Film Distribution Australia | false | false |
| 47 | 32 | Diary of the Dead | $6,080 | -70.9% | 15 | -27 | $405 | $851,555 | 4 | Optimum Releasing | false | false |
| 48 | 42 | The Edge of Heaven | $5,635 | -45.9% | 2 | -2 | $2,817 | $259,787 | 6 | Artificial Eye | false | false |
| 49 | 47 | The Bucket List | $5,027 | -4.4% | 12 | +3 | $418 | $3,985,673 | 7 | Warner Bros. | false | false |
| 50 | 30 | Jodhaa Akbar | $4,088 | -80.9% | 4 | -2 | $1,022 | $2,003,157 | 7 | UTV Motion Pictures | false | false |
| 51 | 33 | Rambo | $4,042 | -80.5% | 7 | -14 | $577 | $6,318,249 | 6 | Sony Pictures Releasing | false | false |
| 52 | 53 | Atonement | $3,430 | -4.1% | 2 | - | $1,715 | $23,934,714 | 30 | Universal Pictures International (UPI) | false | false |
| 53 | 67 | Redacted | $3,184 | +241.3% | 4 | +3 | $796 | $26,441 | 3 | Optimum Releasing | false | false |
| 54 | 40 | Flight of the Red Balloon | $2,502 | -77.4% | 3 | -2 | $834 | $73,163 | 3 | Park Circus | false | false |
| 55 | - | The Book of Revelation | $2,481 | - | 1 | - | $2,481 | $2,481 | 1 | The Works UK Distribution | true | false |
| 56 | 43 | Under the Bombs | $2,050 | -78.7% | 1 | -1 | $2,050 | $21,928 | 2 | Artificial Eye | false | false |
| 57 | - | The Go Master | $2,026 | - | 1 | - | $2,026 | $2,026 | 1 | ICA Films | true | false |
| 58 | 38 | St. Trinian's | $1,994 | -83.1% | 10 | -31 | $199 | $24,487,595 | 15 | Entertainment Film Distributors | false | false |
| 59 | 49 | Underdog | $1,908 | -56.5% | 9 | -6 | $212 | $2,353,272 | 9 | Walt Disney Pictures | false | false |
| 60 | 54 | We Are Together | $1,864 | -36.6% | 2 | +1 | $932 | $42,965 | 4 | Shooting People | false | false |
| 61 | 65 | 4 Months, 3 Weeks and 2 Days | $1,605 | +64.3% | 4 | - | $401 | $582,576 | 13 | Artificial Eye | false | false |
| 62 | 55 | Lust, Caution | $1,372 | -52.8% | 2 | +1 | $686 | $2,072,318 | 13 | Universal Pictures International (UPI) | false | false |
| 63 | 73 | Children of Glory | $1,332 | +489.4% | 2 | - | $666 | $20,355 | 3 | Lionsgate | false | false |
| 64 | 61 | Away from Her | $1,137 | -28.8% | 2 | -3 | $568 | $291,318 | 7 | Metrodome Distribution | false | false |
| 65 | 64 | Bunny Chow: Know Thyself | $1,093 | -7% | 1 | - | $1,093 | $3,458 | 2 | - | false | false |
| 66 | 68 | In the Valley of Elah | $903 | -2.2% | 1 | -2 | $903 | $1,722,931 | 10 | Optimum Releasing | false | false |
| 67 | 56 | P.S. I Love You | $877 | -67.5% | 1 | -2 | $877 | $21,195,924 | 15 | Momentum Pictures | false | false |
| 68 | - | Four Minutes | $716 | - | 1 | - | $716 | $10,375 | 4 | Peccadillo Pictures | false | false |
| 69 | 57 | Azur & Asmar: The Princes' Quest | $696 | -73.9% | 5 | -3 | $139 | $65,151 | 8 | Soda Pictures | false | false |
| 70 | 66 | Mister Lonely | $528 | -45.6% | 1 | - | $528 | $22,849 | 3 | Tartan | false | false |
| 71 | 70 | The 11th Hour | $413 | -17.4% | 1 | - | $413 | $1,460 | 2 | Warner Bros. | false | false |
| 72 | 75 | Asterix at the Olympic Games | $251 | +164.2% | 1 | - | $251 | $40,905 | 9 | Pathé | false | false |
| 73 | - | Paranoid Park | $167 | - | 1 | - | $167 | $196,379 | 14 | Tartan | false | false |
| 74 | 51 | Still Life | $40 | -99% | 1 | -3 | $40 | $67,248 | 9 | British Film Institute (BFI) | false | false |
| 75 | 78 | The Counterfeiters | $40 | - | 1 | - | $40 | $1,314,489 | 25 | Metrodome Distribution | false | false |
