| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Game Plan | $270,090 | - | 55 | - | $4,910 | $270,090 | 1 | Ster-Kinekor Pictures | true | false |
| 2 | 1 | Step Up 2: The Streets | $177,591 | -23.2% | 52 | +1 | $3,415 | $520,803 | 2 | NuMetro Distribution | false | false |
| 3 | - | 10,000 BC | $172,356 | - | 55 | - | $3,133 | $172,356 | 1 | NuMetro Distribution | true | false |
| 4 | 2 | Fool's Gold | $99,178 | -19.4% | 59 | -1 | $1,680 | $534,892 | 3 | NuMetro Distribution | false | false |
| 5 | - | The Spiderwick Chronicles | $73,429 | - | 54 | - | $1,359 | $73,429 | 1 | United International Pictures | true | false |
| 6 | 3 | Juno | $60,429 | -7% | 31 | - | $1,949 | $175,420 | 2 | NuMetro Distribution | false | false |
| 7 | 5 | Why Did I Get Married? | $54,724 | -1.7% | 26 | +2 | $2,104 | $384,485 | 4 | Ster-Kinekor Pictures | false | false |
| 8 | 4 | Jumper | $41,069 | -29.8% | 48 | -13 | $855 | $818,360 | 6 | NuMetro Distribution | false | false |
| 9 | 8 | One Missed Call | $36,224 | -3.5% | 30 | - | $1,207 | $98,093 | 2 | NuMetro Distribution | false | false |
| 10 | 6 | The Water Horse | $30,886 | -43.7% | 33 | -2 | $935 | $179,265 | 3 | United International Pictures | false | false |
| 11 | 7 | Sydney White | $24,935 | -47.6% | 35 | -6 | $712 | $284,270 | 4 | NuMetro Distribution | false | false |
| 12 | 10 | Michael Clayton | $21,845 | -1.3% | 16 | -2 | $1,365 | $232,458 | 5 | NuMetro Distribution | false | false |
| 13 | 13 | No Country for Old Men | $17,055 | -12.5% | 11 | -1 | $1,550 | $143,856 | 4 | United International Pictures | false | false |
| 14 | 14 | The Kite Runner | $16,084 | +29.5% | 10 | -3 | $1,608 | $203,343 | 6 | United International Pictures | false | false |
| 15 | 12 | Love in the Time of Cholera | $14,550 | -28.2% | 21 | - | $692 | $45,469 | 2 | United International Pictures | false | false |
| 16 | 9 | Charlie Wilson's War | $12,833 | -63.4% | 14 | -30 | $916 | $134,622 | 3 | United International Pictures | false | false |
| 17 | - | The Diving Bell and the Butterfly | $10,642 | - | 4 | - | $2,660 | $10,642 | 1 | Ster-Kinekor Pictures | true | false |
| 18 | 17 | There Will Be Blood | $8,758 | -8.4% | 7 | - | $1,251 | $45,506 | 3 | Ster-Kinekor Pictures | false | false |
| 19 | 15 | Atonement | $8,130 | -17.5% | 10 | -4 | $813 | $361,879 | 8 | United International Pictures | false | false |
| 20 | 19 | Jodhaa Akbar | $6,739 | -7.3% | 7 | +2 | $962 | $126,459 | 6 | Ster-Kinekor Pictures | false | false |
| 21 | 16 | National Treasure: Book of Secrets | $4,837 | -50.5% | 11 | -7 | $439 | $1,392,475 | 11 | Ster-Kinekor Pictures | false | false |
| 22 | 20 | Good Luck Chuck | $2,890 | -37.3% | 8 | -2 | $361 | $389,640 | 9 | United International Pictures | false | false |
| 23 | 22 | This Christmas | $1,110 | -6% | 3 | - | $370 | $197,325 | 14 | Ster-Kinekor Pictures | false | false |
| 24 | 23 | Into the Wild | $236 | +19.8% | 1 | -2 | $236 | $76,891 | 9 | United International Pictures | false | false |
