| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | 10,000 BC | $284,029 | +2% | 61 | +5 | $4,656 | $1,326,720 | 3 | Warner Bros. | false | false |
| 2 | 2 | Horton Hears a Who! | $241,478 | -0.1% | 99 | +7 | $2,439 | $596,717 | 2 | 20th Century Fox International | false | false |
| 3 | - | The Spiderwick Chronicles | $155,251 | - | 48 | - | $3,234 | $193,135 | 1 | United International Pictures | true | false |
| 4 | 3 | No Country for Old Men | $125,567 | +0.3% | 40 | - | $3,139 | $591,461 | 3 | Walt Disney Pictures | false | false |
| 5 | 6 | Death at a Funeral | $111,646 | +52.6% | 24 | +8 | $4,651 | $320,974 | 3 | - | false | false |
| 6 | 4 | The Orphanage | $95,697 | -7.9% | 35 | +2 | $2,734 | $250,970 | 2 | CDI Films | false | false |
| 7 | 5 | The Bucket List | $85,220 | -5.6% | 56 | -2 | $1,521 | $1,648,797 | 7 | Warner Bros. | false | false |
| 8 | - | The Hunting Party | $82,449 | - | 30 | - | $2,748 | $98,517 | 1 | Distribution Company | true | false |
| 9 | - | Diary of the Dead | $68,849 | - | 28 | - | $2,458 | $86,056 | 1 | Pachamama Cine | true | false |
| 10 | 7 | The Game Plan | $49,838 | -5.8% | 41 | -4 | $1,215 | $1,236,151 | 6 | Walt Disney Pictures | false | false |
| 11 | - | The Darjeeling Limited | $43,112 | - | 12 | - | $3,592 | $50,647 | 1 | 20th Century Fox International | true | false |
| 12 | - | The Ugly Duckling and Me! | $29,386 | - | 54 | - | $544 | $37,045 | 1 | - | true | false |
| 13 | 9 | P.S. I Love You | $24,111 | -29.5% | 21 | -8 | $1,148 | $275,061 | 4 | Alfa Films | false | false |
| 14 | 8 | Vantage Point | $18,637 | -46% | 27 | -11 | $690 | $346,584 | 4 | Sony Pictures Releasing | false | false |
| 15 | 17 | 3:10 to Yuma | $18,535 | +36.9% | 17 | -3 | $1,090 | $217,413 | 4 | Distribution Company | false | false |
| 16 | 13 | Juno | $15,252 | -31.8% | 16 | -6 | $953 | $436,541 | 6 | Alfa Films | false | false |
| 17 | 15 | Atonement | $11,070 | -29.5% | 14 | -4 | $790 | $481,763 | 7 | United International Pictures | false | false |
| 18 | 11 | The Eye | $10,447 | -58.4% | 12 | -12 | $870 | $190,255 | 4 | United International Pictures | false | false |
| 19 | 14 | Fool's Gold | $9,690 | -41.9% | 16 | -6 | $605 | $108,193 | 4 | Warner Bros. | false | false |
| 20 | 19 | The Water Horse | $9,024 | -23.6% | 29 | - | $311 | $555,513 | 7 | Sony Pictures Releasing | false | false |
| 21 | 10 | Elizabeth: The Golden Age | $8,479 | -67.5% | 4 | -6 | $2,119 | $43,690 | 2 | United International Pictures | false | false |
| 22 | 20 | Love in the Time of Cholera | $7,678 | -30.1% | 20 | -3 | $383 | $579,231 | 10 | 20th Century Fox International | false | false |
| 23 | 27 | Rambo | $5,419 | -5.1% | 15 | -2 | $361 | $305,053 | 5 | CDI Films | false | false |
| 24 | 16 | Sweeney Todd: The Demon Barber of Fleet Street | $5,020 | -66.5% | 19 | -16 | $264 | $644,454 | 6 | Warner Bros. | false | false |
| 25 | 23 | Cloverfield | $4,732 | -35% | 12 | -4 | $394 | $631,114 | 7 | United International Pictures | false | false |
| 26 | 22 | Eastern Promises | $4,646 | -54% | 9 | -11 | $516 | $418,440 | 6 | Distribution Company | false | false |
| 27 | 24 | An American Haunting | $4,627 | -35.4% | 9 | -5 | $514 | $522,154 | 8 | Distribution Company | false | false |
| 28 | 12 | There Will Be Blood | $4,213 | -82.7% | 24 | -11 | $175 | $461,825 | 5 | Walt Disney Pictures | false | false |
| 29 | 26 | Explosive Brigade: Pirate Mission | $4,138 | -27.8% | 18 | -4 | $229 | $760,949 | 8 | Argentina Sono Film S.A.C.I. | false | false |
| 30 | 25 | Charlie Wilson's War | $4,022 | -35.6% | 8 | -8 | $502 | $849,114 | 9 | United International Pictures | false | false |
| 31 | 21 | Away from Her | $3,666 | -65.6% | 10 | -7 | $366 | $159,239 | 5 | Distribution Company | false | false |
| 32 | 33 | Hannibal Rising | $2,256 | +32.3% | 6 | +1 | $376 | $80,757 | 5 | United International Pictures | false | false |
| 33 | 34 | Enchanted | $1,598 | +28.3% | 10 | -5 | $159 | $2,790,481 | 12 | Walt Disney Pictures | false | false |
| 34 | 29 | 1408 | $1,547 | -29.6% | 2 | -3 | $773 | $237,606 | 9 | United International Pictures | false | false |
| 35 | 32 | 27 Dresses | $1,522 | -14.4% | 5 | -1 | $304 | $285,747 | 7 | 20th Century Fox International | false | false |
| 36 | 30 | The Wayward Cloud 2007 Re-release | $1,222 | -42.5% | 1 | -1 | $1,222 | $18,785 | 4 | 791 Cine | false | false |
| 37 | 38 | National Treasure: Book of Secrets | $1,015 | +44.2% | 7 | -4 | $145 | $1,661,327 | 10 | Walt Disney Pictures | false | false |
| 38 | 44 | The Golden Compass | $773 | +151% | 3 | -1 | $257 | $1,387,531 | 15 | Distribution Company | false | false |
| 39 | 18 | Angel-A | $770 | -93.6% | 1 | -9 | $770 | $17,303 | 2 | Distribution Company | false | false |
| 40 | 40 | Hitman | $659 | +1.9% | 4 | +2 | $164 | $183,546 | 9 | 20th Century Fox International | false | false |
| 41 | 36 | Aliens vs. Predator: Requiem | $609 | -26.5% | 9 | - | $67 | $691,475 | 11 | 20th Century Fox International | false | false |
| 42 | 41 | Alvin and the Chipmunks | $549 | +10.2% | 6 | -2 | $91 | $793,957 | 12 | 20th Century Fox International | false | false |
| 43 | 49 | Bee Movie | $451 | +103.2% | 5 | +1 | $90 | $1,469,274 | 16 | United International Pictures | false | false |
| 44 | 31 | Possible Lives | $265 | -87.3% | 3 | -2 | $88 | $18,003 | 7 | Primer Plano Film Group | false | false |
| 45 | 35 | Sleuth | $251 | -78.9% | 3 | - | $83 | $165,449 | 11 | Sony Pictures Releasing | false | false |
| 46 | 53 | I Am Legend | $146 | -12.6% | 4 | -1 | $36 | $2,078,983 | 13 | Warner Bros. | false | false |
| 47 | 39 | Gone Baby Gone | $101 | -85.3% | 1 | -2 | $101 | $422,646 | 18 | Walt Disney Pictures | false | false |
| 48 | 58 | Underdog | $59 | +156.5% | 2 | +1 | $29 | $849,476 | 25 | Walt Disney Pictures | false | false |
| 49 | 47 | Giants of Valdes | $57 | -75.1% | 2 | - | $28 | $82,732 | 10 | Primer Plano Film Group | false | false |
| 50 | 51 | Tres minutos | $48 | -73% | 2 | - | $24 | $6,691 | 5 | Primer Plano Film Group | false | false |
