| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Game Plan | $222,731 | -6.4% | 47 | -2 | $4,738 | $953,177 | 3 | Walt Disney Pictures | false | false |
| 2 | 2 | The Bucket List | $170,021 | -7.5% | 62 | +3 | $2,742 | $1,213,763 | 4 | Warner Bros. | false | false |
| 3 | - | Vantage Point | $153,467 | - | 46 | - | $3,336 | $153,467 | 1 | Sony Pictures Releasing | true | false |
| 4 | 3 | There Will Be Blood | $118,493 | -15.4% | 36 | - | $3,291 | $315,858 | 2 | Walt Disney Pictures | false | false |
| 5 | - | 3:10 to Yuma | $96,552 | - | 32 | - | $3,017 | $96,552 | 1 | Distribution Company | true | false |
| 6 | - | P.S. I Love You | $94,823 | - | 28 | - | $3,386 | $94,823 | 1 | Alfa Films | true | false |
| 7 | 5 | Sweeney Todd: The Demon Barber of Fleet Street | $81,063 | -30.7% | 43 | -2 | $1,885 | $545,605 | 3 | Warner Bros. | false | false |
| 8 | - | The Eye | $76,337 | - | 24 | - | $3,180 | $76,337 | 1 | United International Pictures | true | false |
| 9 | 4 | Rambo | $70,090 | -40.9% | 47 | -2 | $1,491 | $243,771 | 2 | CDI Films | false | false |
| 10 | 6 | Eastern Promises | $66,854 | -14.9% | 38 | -1 | $1,759 | $342,353 | 3 | Distribution Company | false | false |
| 11 | 7 | Juno | $65,159 | -16% | 28 | -3 | $2,327 | $310,591 | 3 | Alfa Films | false | false |
| 12 | 10 | The Water Horse | $64,078 | +5.4% | 32 | - | $2,002 | $486,175 | 4 | Sony Pictures Releasing | false | false |
| 13 | 8 | Cloverfield | $48,230 | -23% | 35 | -5 | $1,378 | $579,116 | 4 | United International Pictures | false | false |
| 14 | - | Fool's Gold | $41,131 | - | 20 | - | $2,056 | $41,131 | 1 | Warner Bros. | true | false |
| 15 | 12 | Explosive Brigade: Pirate Mission | $36,826 | -26.2% | 51 | -20 | $722 | $724,957 | 5 | Argentina Sono Film S.A.C.I. | false | false |
| 16 | 9 | Away from Her | $32,644 | -46.9% | 19 | -2 | $1,718 | $115,814 | 2 | Distribution Company | false | false |
| 17 | 11 | Atonement | $31,411 | -43.1% | 20 | -14 | $1,570 | $418,039 | 4 | United International Pictures | false | false |
| 18 | 13 | An American Haunting | $29,476 | -34.6% | 34 | +1 | $866 | $483,802 | 5 | Distribution Company | false | false |
| 19 | 15 | Love in the Time of Cholera | $27,823 | +4.5% | 31 | - | $897 | $516,812 | 7 | 20th Century Fox International | false | false |
| 20 | 17 | Charlie Wilson's War | $19,210 | -22.9% | 33 | - | $582 | $816,297 | 6 | United International Pictures | false | false |
| 21 | 14 | Hannibal Rising | $15,412 | -57.7% | 18 | -9 | $856 | $69,517 | 2 | United International Pictures | false | false |
| 22 | 16 | National Treasure: Book of Secrets | $11,992 | -52.8% | 37 | -22 | $324 | $1,653,496 | 7 | Walt Disney Pictures | false | false |
| 23 | 18 | 27 Dresses | $11,922 | -41.2% | 25 | -1 | $476 | $268,866 | 4 | 20th Century Fox International | false | false |
| 24 | 19 | Enchanted | $11,645 | -25.1% | 37 | -28 | $314 | $2,785,842 | 9 | Walt Disney Pictures | false | false |
| 25 | 22 | Alvin and the Chipmunks | $10,254 | -5.4% | 29 | -13 | $353 | $787,365 | 9 | 20th Century Fox International | false | false |
| 26 | 20 | Aliens vs. Predator: Requiem | $8,756 | -25.4% | 25 | -7 | $350 | $678,955 | 8 | 20th Century Fox International | false | false |
| 27 | - | The Wayward Cloud 2007 Re-release | $7,044 | - | 2 | - | $3,522 | $7,044 | 1 | 791 Cine | true | false |
| 28 | 21 | Hitman | $4,100 | -64% | 15 | -8 | $273 | $177,330 | 6 | 20th Century Fox International | false | false |
| 29 | 44 | I Could Never Be Your Woman | $3,733 | +1,375.5% | 9 | +8 | $414 | $297,422 | 9 | CDI Films | false | false |
| 30 | 24 | 1408 | $3,004 | -52.3% | 8 | -3 | $375 | $230,141 | 6 | United International Pictures | false | false |
| 31 | 23 | Bratz | $2,119 | -73.3% | 5 | -17 | $423 | $43,400 | 3 | Pachamama Cine | false | false |
| 32 | 32 | Tres minutos | $1,777 | -13.3% | 5 | - | $355 | $5,163 | 2 | Primer Plano Film Group | false | false |
| 33 | 29 | I Do: How to Get Married and Stay Single | $1,570 | -38.4% | 3 | -2 | $523 | $70,411 | 6 | Alfa Films | false | false |
| 34 | 35 | Bridge to Terabithia | $1,411 | +95.2% | 5 | +3 | $282 | $97,738 | 8 | United International Pictures | false | false |
| 35 | 28 | Gone Baby Gone | $1,225 | -70.3% | 6 | -4 | $204 | $418,940 | 15 | Walt Disney Pictures | false | false |
| 36 | 25 | I Am Legend | $1,224 | -77.8% | 9 | -11 | $136 | $2,080,734 | 10 | Warner Bros. | false | false |
| 37 | - | La Vie En Rose | $1,167 | - | 2 | - | $583 | $495,377 | 43 | Alfa Films | false | false |
| 38 | 27 | The Heartbreak Kid | $1,056 | -76.9% | 5 | -7 | $211 | $914,153 | 17 | United International Pictures | false | false |
| 39 | 38 | The Cave of the Yellow Dog 2008 Re-release | $995 | +156.4% | 2 | +1 | $497 | $28,271 | 5 | IFA | false | false |
| 40 | 48 | The Golden Compass | $987 | +532.7% | 2 | +1 | $493 | $1,387,747 | 12 | Distribution Company | false | false |
| 41 | 30 | American Gangster | $896 | -62.9% | 6 | -5 | $149 | $762,627 | 9 | United International Pictures | false | false |
| 42 | 47 | 4 Months, 3 Weeks and 2 Days | $716 | +333.9% | 3 | +2 | $238 | $203,488 | 13 | Pachamama Cine | false | false |
| 43 | 26 | Beowulf | $574 | -88.3% | 1 | - | $574 | $706,590 | 15 | Warner Bros. | false | false |
| 44 | - | Michael Clayton | $522 | - | 2 | - | $261 | $574,063 | 21 | Alfa Films | false | false |
| 45 | 41 | Possible Lives | $479 | +38.4% | 2 | - | $239 | $11,752 | 4 | Primer Plano Film Group | false | false |
| 46 | 33 | My Best Friend | $457 | -63% | 2 | -2 | $228 | $123,932 | 9 | Alfa Films | false | false |
| 47 | 36 | Bordertown | $446 | -32% | 1 | -2 | $446 | $60,948 | 7 | Distribution Company | false | false |
| 48 | 37 | Bee Movie | $370 | -41.5% | 3 | -2 | $123 | $1,470,480 | 13 | United International Pictures | false | false |
| 49 | 40 | Giants of Valdes | $340 | -9.6% | 2 | - | $170 | $81,860 | 7 | Primer Plano Film Group | false | false |
| 50 | 53 | Suspiros del corazón | $297 | +386.9% | 1 | - | $297 | $7,383 | 8 | Primer Plano Film Group | false | false |
| 51 | 42 | After the Wedding | $291 | +2.1% | 2 | +1 | $145 | $107,650 | 15 | Alfa Films | false | false |
| 52 | - | Shattered | $203 | - | 1 | - | $203 | $324,918 | 17 | Distribution Company | false | false |
| 53 | 49 | Lights in the Dusk | $165 | +32% | 1 | - | $165 | $52,231 | 23 | Alfa Films | false | false |
| 54 | - | Lonely Hearts | $139 | - | 1 | - | $139 | $100,016 | 14 | Distribution Company | false | false |
| 55 | 50 | Encarnacion | $137 | +11.4% | 1 | - | $137 | $41,244 | 21 | Distribution Company | false | false |
| 56 | 51 | Underdog | $124 | +12.7% | 3 | -1 | $41 | $850,780 | 22 | Walt Disney Pictures | false | false |
| 57 | 34 | Sleuth | $72 | -93.6% | 1 | -5 | $72 | $155,356 | 8 | Sony Pictures Releasing | false | false |
| 58 | 52 | At Five in the Afternoon | $46 | -40.3% | 1 | - | $46 | $16,073 | 14 | 791 Cine | false | false |
