| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Game Plan | $237,865 | +3.3% | 49 | +6 | $4,854 | $599,346 | 2 | Walt Disney Pictures | false | false |
| 2 | 2 | The Bucket List | $183,858 | -17.5% | 59 | -3 | $3,116 | $967,680 | 3 | Warner Bros. | false | false |
| 3 | - | There Will Be Blood | $140,103 | - | 36 | - | $3,891 | $140,103 | 1 | Walt Disney Pictures | true | false |
| 4 | - | Rambo | $118,600 | - | 49 | - | $2,420 | $118,600 | 1 | CDI Films | true | false |
| 5 | 3 | Sweeney Todd: The Demon Barber of Fleet Street | $117,051 | -46.1% | 45 | -1 | $2,601 | $410,556 | 2 | Warner Bros. | false | false |
| 6 | 4 | Eastern Promises | $78,585 | -34.8% | 39 | -4 | $2,015 | $243,022 | 2 | Distribution Company | false | false |
| 7 | 6 | Juno | $77,597 | -14.3% | 31 | -10 | $2,503 | $204,952 | 2 | Alfa Films | false | false |
| 8 | 5 | Cloverfield | $62,639 | -39.8% | 40 | -5 | $1,565 | $503,988 | 3 | United International Pictures | false | false |
| 9 | - | Away from Her | $61,423 | - | 21 | - | $2,924 | $61,423 | 1 | Distribution Company | true | false |
| 10 | 10 | The Water Horse | $60,784 | +13% | 32 | -6 | $1,899 | $384,732 | 3 | Sony Pictures Releasing | false | false |
| 11 | 7 | Atonement | $55,202 | -21.6% | 34 | -9 | $1,623 | $363,175 | 3 | United International Pictures | false | false |
| 12 | 8 | Explosive Brigade: Pirate Mission | $49,868 | -25.7% | 71 | -25 | $702 | $660,102 | 4 | Argentina Sono Film S.A.C.I. | false | false |
| 13 | 9 | An American Haunting | $45,045 | -22.7% | 33 | -6 | $1,365 | $435,103 | 4 | Distribution Company | false | false |
| 14 | - | Hannibal Rising | $36,478 | - | 27 | - | $1,351 | $36,478 | 1 | United International Pictures | true | false |
| 15 | 15 | Love in the Time of Cholera | $26,632 | +20.5% | 31 | +4 | $859 | $472,620 | 6 | 20th Century Fox International | false | false |
| 16 | 13 | National Treasure: Book of Secrets | $25,380 | -38.5% | 59 | -11 | $430 | $1,627,523 | 6 | Walt Disney Pictures | false | false |
| 17 | 11 | Charlie Wilson's War | $24,926 | -46.2% | 33 | -11 | $755 | $785,354 | 5 | United International Pictures | false | false |
| 18 | 12 | 27 Dresses | $20,281 | -54.4% | 26 | -27 | $780 | $246,797 | 3 | 20th Century Fox International | false | false |
| 19 | 14 | Enchanted | $15,546 | -49.4% | 65 | -37 | $239 | $2,760,404 | 8 | Walt Disney Pictures | false | false |
| 20 | 16 | Aliens vs. Predator: Requiem | $11,741 | -35.6% | 32 | -6 | $366 | $663,969 | 7 | 20th Century Fox International | false | false |
| 21 | 20 | Hitman | $11,379 | +27.2% | 23 | +6 | $494 | $167,201 | 5 | 20th Century Fox International | false | false |
| 22 | 19 | Alvin and the Chipmunks | $10,840 | -22% | 42 | -11 | $258 | $770,283 | 8 | 20th Century Fox International | false | false |
| 23 | 18 | Bratz | $7,927 | -52.8% | 22 | -5 | $360 | $35,680 | 2 | Pachamama Cine | false | false |
| 24 | 24 | 1408 | $6,298 | +2.3% | 11 | +2 | $572 | $224,841 | 5 | United International Pictures | false | false |
| 25 | 17 | I Am Legend | $5,511 | -69.2% | 20 | -22 | $275 | $2,076,651 | 9 | Warner Bros. | false | false |
| 26 | 33 | Beowulf | $4,901 | +864.8% | 1 | -2 | $4,901 | $876,770 | 14 | Warner Bros. | false | false |
| 27 | 23 | The Heartbreak Kid | $4,578 | -27.5% | 12 | -3 | $381 | $911,034 | 16 | United International Pictures | false | false |
| 28 | 21 | Gone Baby Gone | $4,130 | -36.9% | 10 | -2 | $413 | $416,045 | 14 | Walt Disney Pictures | false | false |
| 29 | 31 | I Do: How to Get Married and Stay Single | $2,550 | +254.2% | 5 | +2 | $510 | $67,284 | 5 | Alfa Films | false | false |
| 30 | 22 | American Gangster | $2,412 | -62.4% | 11 | -3 | $219 | $760,805 | 8 | United International Pictures | false | false |
| 31 | 25 | The Kite Runner | $2,342 | -55% | 5 | -7 | $468 | $9,909 | 2 | United International Pictures | false | false |
| 32 | - | Tres minutos | $2,050 | - | 5 | - | $410 | $2,050 | 1 | Primer Plano Film Group | true | false |
| 33 | 37 | My Best Friend | $1,234 | +308.6% | 4 | +1 | $308 | $122,780 | 8 | Alfa Films | false | false |
| 34 | 26 | Sleuth | $1,128 | -75.6% | 6 | -6 | $188 | $156,567 | 7 | Sony Pictures Releasing | false | false |
| 35 | - | Bridge to Terabithia | $723 | - | 2 | - | $361 | $95,875 | 7 | United International Pictures | false | false |
| 36 | 34 | Bordertown | $656 | +30.2% | 3 | +2 | $218 | $60,365 | 6 | Distribution Company | false | false |
| 37 | 32 | Bee Movie | $633 | +3.9% | 5 | +2 | $126 | $1,469,730 | 12 | United International Pictures | false | false |
| 38 | 29 | The Cave of the Yellow Dog 2008 Re-release | $388 | -77.9% | 1 | -2 | $388 | $27,044 | 4 | IFA | false | false |
| 39 | 28 | The Assassination of Jesse James by the Coward Robert Ford | $379 | -80.4% | 3 | -3 | $126 | $156,490 | 13 | Warner Bros. | false | false |
| 40 | 30 | Giants of Valdes | $376 | -74.5% | 2 | -4 | $188 | $81,380 | 6 | Primer Plano Film Group | false | false |
| 41 | 27 | Possible Lives | $346 | -85.4% | 2 | -3 | $173 | $11,124 | 3 | Primer Plano Film Group | false | false |
| 42 | 36 | After the Wedding | $285 | -24.8% | 1 | -1 | $285 | $107,194 | 14 | Alfa Films | false | false |
| 43 | 38 | August Rush | $259 | -5.5% | 2 | +1 | $129 | $70,284 | 7 | Distribution Company | false | false |
| 44 | 47 | I Could Never Be Your Woman | $253 | +232.9% | 1 | - | $253 | $293,905 | 8 | CDI Films | false | false |
| 45 | - | The Black Dahlia | $233 | - | 1 | - | $233 | $62,360 | 14 | United International Pictures | false | false |
| 46 | 35 | Café Lumière 2007 Re-release | $203 | -56.5% | 1 | -1 | $203 | $51,258 | 11 | 791 Cine | false | false |
| 47 | 39 | 4 Months, 3 Weeks and 2 Days | $165 | -24% | 1 | - | $165 | $202,662 | 12 | Pachamama Cine | false | false |
| 48 | 40 | The Golden Compass | $156 | +4% | 1 | -10 | $156 | $1,386,348 | 11 | Distribution Company | false | false |
| 49 | 46 | Lights in the Dusk | $125 | +15.7% | 1 | - | $125 | $52,054 | 22 | Alfa Films | false | false |
| 50 | 42 | Encarnacion | $123 | +4.2% | 1 | -2 | $123 | $41,045 | 20 | Distribution Company | false | false |
| 51 | 49 | Underdog | $110 | +746.2% | 4 | +3 | $27 | $850,601 | 21 | Walt Disney Pictures | false | false |
| 52 | - | At Five in the Afternoon | $77 | - | 1 | - | $77 | $16,048 | 13 | 791 Cine | false | false |
| 53 | 43 | Suspiros del corazón | $61 | -48.3% | 1 | - | $61 | $7,055 | 7 | Primer Plano Film Group | false | false |
| 54 | - | Whisper | $33 | - | 1 | - | $33 | $111,584 | 13 | Alfa Films | false | false |
| 55 | - | Saw IV | $25 | - | 1 | - | $25 | $1,012,487 | 17 | Walt Disney Pictures | false | false |
| 56 | - | Lions for Lambs | $19 | - | 1 | - | $19 | $507,077 | 15 | 20th Century Fox International | false | false |
