| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Sweeney Todd: The Demon Barber of Fleet Street | $258,276 | - | 31 | - | $8,331 | $258,276 | 1 | N/A | true | false |
| 2 | 1 | Rambo | $186,251 | -34.3% | 39 | - | $4,775 | $575,443 | 2 | N/A | false | false |
| 3 | 2 | 27 Dresses | $151,811 | -39.2% | 27 | - | $5,622 | $584,124 | 2 | N/A | false | false |
| 4 | 3 | The Mist | $95,935 | -46.2% | 21 | +1 | $4,568 | $319,971 | 2 | N/A | false | false |
| 5 | 5 | The House | $48,166 | -24.8% | 18 | - | $2,675 | $154,414 | 2 | N/A | false | false |
| 6 | 4 | Cloverfield | $43,339 | -63.1% | 29 | - | $1,494 | $677,751 | 3 | N/A | false | false |
| 7 | 6 | Atonement | $36,793 | -35.7% | 10 | - | $3,679 | $108,358 | 2 | N/A | false | false |
| 8 | - | The Kite Runner | $23,244 | - | 2 | - | $11,622 | $29,013 | 1 | N/A | true | false |
| 9 | 7 | American Gangster | $20,253 | -44.5% | 15 | -9 | $1,350 | $494,839 | 4 | N/A | false | false |
| 10 | 8 | The Assassination of Jesse James by the Coward Robert Ford | $8,723 | -40.6% | 4 | - | $2,180 | $27,028 | 2 | N/A | false | false |
| 11 | - | Gone Baby Gone | $7,122 | - | 2 | - | $3,561 | $7,976 | 1 | N/A | true | false |
| 12 | 9 | Le Grand Chef | $4,982 | -62.9% | 8 | -5 | $622 | $216,374 | 4 | N/A | false | false |
| 13 | 17 | Michael Clayton | $4,298 | +6.9% | 3 | +1 | $1,432 | $103,629 | 5 | N/A | false | false |
| 14 | 14 | Dan in Real Life | $2,815 | -39.5% | 1 | -3 | $2,815 | $122,145 | 4 | N/A | false | false |
| 15 | 11 | Body | $2,707 | -73.1% | 7 | -10 | $386 | $261,987 | 4 | N/A | false | false |
| 16 | 10 | One Missed Call | $2,232 | -83.2% | 4 | -13 | $558 | $334,649 | 4 | N/A | false | false |
| 17 | 12 | Death Sentence | $2,049 | -70.2% | 2 | -1 | $1,024 | $14,170 | 2 | N/A | false | false |
| 18 | - | I Am Legend | $1,799 | - | 3 | - | $599 | $2,209,266 | 6 | N/A | false | false |
| 19 | 15 | The Savages | $1,203 | -72.9% | 1 | -2 | $1,203 | $20,846 | 3 | N/A | false | false |
| 20 | 27 | Elizabeth: The Golden Age | $965 | +344.7% | 2 | +1 | $482 | $121,620 | 6 | N/A | false | false |
| 21 | 16 | 3:10 to Yuma | $909 | -78.6% | 4 | - | $227 | $24,170 | 3 | N/A | false | false |
| 22 | 18 | The Flock | $776 | -77.2% | 2 | -2 | $388 | $18,737 | 3 | N/A | false | false |
| 23 | 13 | Aliens vs. Predator: Requiem | $577 | -89.8% | 2 | -12 | $288 | $1,353,607 | 5 | N/A | false | false |
| 24 | 21 | Trade | $435 | -24.2% | 1 | - | $435 | $15,501 | 4 | N/A | false | false |
| 25 | 26 | Enchanted | $312 | +23.3% | 1 | - | $312 | $2,126,303 | 11 | N/A | false | false |
| 26 | 25 | Lust, Caution | $57 | -85.3% | 1 | - | $57 | $1,143,184 | 18 | N/A | false | false |
