| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Cloverfield | $230,514 | - | 35 | - | $6,586 | $230,514 | 1 | N/A | true | false |
| 2 | - | 27 Dresses | $198,104 | - | 28 | - | $7,075 | $191,804 | 1 | N/A | true | false |
| 3 | 1 | Aliens vs. Predator: Requiem | $177,662 | -60.5% | 55 | - | $3,230 | $682,201 | 2 | N/A | false | false |
| 4 | 3 | Rambo | $106,143 | -31.3% | 45 | - | $2,358 | $391,721 | 2 | N/A | false | false |
| 5 | 5 | Alvin and the Chipmunks | $103,458 | -17.5% | 30 | -1 | $3,448 | $537,303 | 3 | N/A | false | false |
| 6 | - | One Missed Call | $99,880 | - | 25 | - | $3,995 | $99,880 | 1 | N/A | true | false |
| 7 | 2 | National Treasure: Book of Secrets | $99,490 | -63.6% | 74 | -16 | $1,344 | $2,295,659 | 4 | N/A | false | false |
| 8 | - | In the Name of the King: A Dungeon Siege Tale | $86,795 | - | 20 | - | $4,339 | $86,795 | 1 | N/A | true | false |
| 9 | - | Saw IV | $74,396 | - | 20 | - | $3,719 | $74,396 | 1 | N/A | true | false |
| 10 | 4 | I Am Legend | $63,525 | -57.7% | 59 | -3 | $1,076 | $1,484,318 | 4 | N/A | false | false |
| 11 | 6 | American Gangster | $22,018 | -67.7% | 24 | -1 | $917 | $108,032 | 2 | N/A | false | false |
| 12 | - | P.S. I Love You | $12,895 | - | 16 | - | $805 | $75,387 | 2 | N/A | false | false |
| 13 | 9 | The Heartbreak Kid | $12,442 | -57.9% | 17 | -7 | $731 | $165,721 | 3 | N/A | false | false |
| 14 | 8 | Sweeney Todd: The Demon Barber of Fleet Street | $10,409 | -76.5% | 13 | -6 | $800 | $207,700 | 3 | N/A | false | false |
| 15 | 7 | Dragon Wars: D-War | $8,431 | -86.4% | 14 | -6 | $602 | $296,962 | 3 | N/A | false | false |
| 16 | 10 | Bee Movie | $2,821 | -84.2% | 14 | -7 | $201 | $313,119 | 4 | N/A | false | false |
