| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Rambo | $283,554 | - | 39 | - | $7,270 | $283,554 | 1 | N/A | true | false |
| 2 | - | 27 Dresses | $249,574 | - | 27 | - | $9,243 | $354,237 | 1 | N/A | true | false |
| 3 | - | The Mist | $178,225 | - | 20 | - | $8,911 | $178,225 | 1 | N/A | true | false |
| 4 | 1 | Cloverfield | $117,388 | -71% | 29 | - | $4,047 | $597,941 | 2 | N/A | false | false |
| 5 | - | The House | $64,013 | - | 18 | - | $3,556 | $82,913 | 1 | N/A | true | false |
| 6 | - | Atonement | $57,228 | - | 10 | - | $5,722 | $57,228 | 1 | N/A | true | false |
| 7 | 2 | American Gangster | $36,494 | -69.2% | 24 | - | $1,520 | $457,535 | 3 | N/A | false | false |
| 8 | - | The Assassination of Jesse James by the Coward Robert Ford | $14,681 | - | 4 | - | $3,670 | $14,681 | 1 | N/A | true | false |
| 9 | 5 | Le Grand Chef | $13,418 | -70.3% | 13 | -2 | $1,032 | $204,180 | 3 | N/A | false | false |
| 10 | 3 | One Missed Call | $13,267 | -79.3% | 17 | -9 | $780 | $323,193 | 3 | N/A | false | false |
| 11 | 4 | Body | $10,077 | -78% | 17 | -1 | $592 | $251,881 | 3 | N/A | false | false |
| 12 | - | Death Sentence | $6,879 | - | 3 | - | $2,293 | $9,196 | 1 | N/A | true | false |
| 13 | 6 | Aliens vs. Predator: Requiem | $5,646 | -84.7% | 14 | -10 | $403 | $1,326,631 | 4 | N/A | false | false |
| 14 | 7 | Dan in Real Life | $4,655 | -80.8% | 4 | -7 | $1,163 | $115,969 | 3 | N/A | false | false |
| 15 | 11 | The Savages | $4,444 | -56.1% | 3 | - | $1,481 | $17,764 | 2 | N/A | false | false |
| 16 | 10 | 3:10 to Yuma | $4,242 | -61.8% | 4 | - | $1,060 | $21,610 | 2 | N/A | false | false |
| 17 | 13 | Michael Clayton | $4,019 | -58% | 2 | -3 | $2,009 | $96,514 | 4 | N/A | false | false |
| 18 | 12 | The Flock | $3,402 | -65.2% | 4 | - | $850 | $16,317 | 2 | N/A | false | false |
| 19 | 17 | Sharkwater | $2,077 | -55.3% | 3 | - | $692 | $12,237 | 2 | N/A | false | false |
| 20 | 23 | Vexille | $868 | +8.1% | 1 | - | $868 | $32,712 | 5 | N/A | false | false |
| 21 | 19 | Trade | $574 | -86% | 1 | - | $574 | $14,475 | 3 | N/A | false | false |
| 22 | 20 | Love in the Time of Cholera | $556 | -85.9% | 1 | -2 | $556 | $15,235 | 3 | N/A | false | false |
| 23 | 9 | National Treasure: Book of Secrets | $555 | -95.6% | 2 | -10 | $277 | $2,187,808 | 6 | N/A | false | false |
| 24 | 15 | Alvin and the Chipmunks | $500 | -92.1% | 1 | -5 | $500 | $1,981,081 | 7 | N/A | false | false |
| 25 | 24 | Lust, Caution | $387 | -51.3% | 1 | - | $387 | $1,122,014 | 17 | N/A | false | false |
| 26 | 28 | Enchanted | $253 | +27.1% | 1 | - | $253 | $2,086,943 | 10 | N/A | false | false |
| 27 | 22 | Elizabeth: The Golden Age | $217 | -84.1% | 1 | -2 | $217 | $118,395 | 5 | N/A | false | false |
| 28 | 30 | Penny Dreadful | $16 | -78.1% | 1 | -3 | $16 | $17,368 | 4 | N/A | false | false |
