| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | 27 Dresses | $1,365,185 | -38.4% | 245 | -4 | $5,572 | $9,656,915 | 3 | 20th Century Fox International | false | false |
| 2 | - | Sweeney Todd: The Demon Barber of Fleet Street | $1,337,426 | - | 127 | - | $10,530 | $1,337,426 | 1 | Warner Bros. | true | false |
| 3 | 5 | Juno | $1,301,492 | -20.3% | 180 | +12 | $7,230 | $3,967,764 | 2 | Walt Disney Studios Motion Pictures | false | false |
| 4 | 3 | Alvin and the Chipmunks | $1,094,068 | -35.5% | 256 | +3 | $4,273 | $13,756,078 | 4 | 20th Century Fox International | false | false |
| 5 | 4 | American Gangster | $904,968 | -46.6% | 232 | -23 | $3,900 | $7,349,775 | 3 | Universal Pictures International (UPI) | false | false |
| 6 | 1 | Cloverfield | $875,874 | -60.8% | 236 | +1 | $3,711 | $3,948,644 | 2 | Paramount Pictures International | false | false |
| 7 | 6 | I Am Legend | $812,908 | -49.2% | 262 | -26 | $3,102 | $18,674,376 | 4 | Roadshow Films | false | false |
| 8 | - | Charlie Wilson's War | $695,835 | - | 126 | - | $5,522 | $726,205 | 1 | Universal Pictures International (UPI) | true | false |
| 9 | 7 | The Water Horse | $607,214 | -35.4% | 194 | -1 | $3,129 | $4,030,778 | 3 | Sony Pictures Releasing | false | false |
| 10 | 9 | Enchanted | $393,783 | -35.3% | 248 | -27 | $1,587 | $10,613,317 | 5 | Walt Disney Pictures | false | false |
| 11 | - | Walk Hard: The Dewey Cox Story | $342,556 | - | 169 | - | $2,026 | $342,556 | 1 | Sony Pictures Releasing | true | false |
| 12 | 10 | Atonement | $338,287 | -40.2% | 149 | -1 | $2,270 | $7,670,445 | 5 | Universal Pictures International (UPI) | false | false |
| 13 | 8 | The Golden Compass | $320,487 | -50.9% | 240 | -37 | $1,335 | $12,522,192 | 5 | Roadshow Films | false | false |
| 14 | 11 | The Kite Runner | $256,695 | -24.6% | 48 | +4 | $5,347 | $759,551 | 2 | Paramount Pictures International | false | false |
| 15 | 14 | No Country for Old Men | $227,484 | +0.5% | 73 | +21 | $3,116 | $3,107,869 | 6 | Paramount Pictures International | false | false |
| 16 | 12 | National Treasure: Book of Secrets | $149,784 | -55.6% | 133 | -55 | $1,126 | $11,368,096 | 6 | Walt Disney Pictures | false | false |
| 17 | 13 | P.S. I Love You | $137,880 | -50.6% | 104 | -36 | $1,325 | $4,765,907 | 5 | Hoyts Distribution | false | false |
| 18 | 15 | Bee Movie | $99,047 | -47.1% | 111 | -42 | $892 | $13,143,730 | 8 | Paramount Pictures International | false | false |
| 19 | 16 | Lust, Caution | $88,444 | -26.3% | 12 | +1 | $7,370 | $299,667 | 2 | Park Circus | false | false |
| 20 | 17 | Two Days in Paris | $69,422 | -41.6% | 24 | +13 | $2,892 | $1,192,148 | 5 | Hopscotch Films | false | false |
| 21 | 18 | Death at a Funeral | $62,648 | -43% | 71 | -11 | $882 | $13,614,117 | 16 | Icon Film Distribution | false | false |
| 22 | 19 | The Darjeeling Limited | $44,709 | -51.4% | 29 | -20 | $1,541 | $1,694,168 | 5 | 20th Century Fox International | false | false |
| 23 | - | Tell No One | $39,225 | - | 3 | - | $13,075 | $260,561 | 12 | Madman Entertainment | false | false |
| 24 | 20 | Aliens vs. Predator: Requiem | $36,325 | -48.2% | 39 | -20 | $931 | $5,007,408 | 5 | 20th Century Fox International | false | false |
| 25 | 23 | Beowulf | $34,936 | -16% | 17 | -4 | $2,055 | $6,568,215 | 9 | Warner Bros. | false | false |
| 26 | 22 | I'm Not There | $34,314 | -25.6% | 20 | -3 | $1,715 | $570,477 | 5 | Icon Film Distribution | false | false |
| 27 | - | Lions for Lambs | $33,985 | - | 2 | - | $16,992 | $2,238,686 | 12 | 20th Century Fox International | false | false |
| 28 | 21 | Mr. Magorium's Wonder Emporium | $26,942 | -43.9% | 44 | -20 | $612 | $4,923,852 | 7 | Roadshow Films | false | false |
| 29 | - | Hunting and Gathering | $26,111 | - | 4 | - | $6,527 | $995,336 | 7 | Palace Films | false | false |
| 30 | 25 | As It Is in Heaven | $21,520 | +26.6% | 8 | - | $2,690 | $2,812,772 | 78 | Rialto Distribution | false | false |
| 31 | - | Sunday | $17,471 | - | 7 | - | $2,495 | $17,471 | 1 | Eros Worldwide | true | false |
| 32 | 29 | Hitman | $12,290 | +79.2% | 16 | +10 | $768 | $3,719,916 | 8 | 20th Century Fox International | false | false |
| 33 | 26 | Conversations with My Gardener | $9,455 | -11% | 5 | - | $1,891 | $414,745 | 12 | Rialto Distribution | false | false |
| 34 | 28 | I Served the King of England | $4,605 | -38.2% | 6 | -1 | $767 | $170,979 | 5 | Rialto Distribution | false | false |
| 35 | 27 | Grindhouse | $2,094 | -80.3% | 1 | - | $2,094 | $28,351 | 7 | Roadshow Films | false | false |
| 36 | 37 | September | $1,755 | +234.3% | 4 | +2 | $438 | $58,738 | 9 | Hopscotch Films | false | false |
| 37 | 33 | The Last Mistress | $1,720 | -37% | 2 | - | $860 | $94,858 | 11 | Potential Films | false | false |
| 38 | 34 | Private Fears in Public Places | $1,029 | -54.8% | 1 | - | $1,029 | $117,739 | 8 | Sharmill Films | false | false |
| 39 | 36 | Michael Clayton | $731 | +28.9% | 6 | +4 | $121 | $3,077,217 | 15 | Roadshow Films | false | false |
| 40 | 38 | Rogue | $709 | +71.3% | 2 | -1 | $354 | $1,574,346 | 12 | Roadshow Films | false | false |
| 41 | 32 | Transylvania | $324 | -89% | 1 | - | $324 | $8,656 | 2 | Potential Films | false | false |
| 42 | - | Death Proof | $193 | - | 3 | - | $64 | $797,976 | 13 | Roadshow Films | false | false |
