| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Love in the Time of Cholera | $13,925 | +0.7% | 5 | - | $2,785 | $89,320 | 3 | N/A | false | false |
| 2 | 1 | I Am Legend | $12,559 | -22.9% | 5 | - | $2,511 | $96,809 | 3 | N/A | false | false |
| 3 | 3 | American Gangster | $9,585 | -5.9% | 8 | - | $1,198 | $54,921 | 2 | N/A | false | false |
| 4 | - | The Game Plan | $9,112 | - | 6 | - | $1,518 | $9,352 | 1 | N/A | true | false |
| 5 | 6 | Aliens vs. Predator: Requiem | $8,571 | +14.1% | 5 | - | $1,714 | $24,077 | 2 | N/A | false | false |
| 6 | 5 | Alvin and the Chipmunks | $7,632 | -5.6% | 5 | - | $1,526 | $52,796 | 3 | N/A | false | false |
| 7 | - | Charlie Wilson's War | $6,769 | - | 1 | - | $6,769 | $6,769 | 1 | N/A | true | false |
| 8 | 7 | Enchanted | $6,293 | -3.5% | 6 | -1 | $1,048 | $86,815 | 5 | N/A | false | false |
| 9 | - | Rendition | $5,375 | - | 4 | - | $1,343 | $5,375 | 1 | N/A | true | false |
| 10 | 4 | The Painted Veil | $4,123 | -51.9% | 4 | -1 | $1,030 | $18,876 | 2 | N/A | false | false |
| 11 | 9 | Michael Clayton | $3,598 | +2.3% | 5 | - | $719 | $42,658 | 5 | N/A | false | false |
| 12 | 8 | The Heartbreak Kid | $3,516 | -41.7% | 3 | -4 | $1,172 | $59,733 | 5 | N/A | false | false |
| 13 | - | Family Hero | $3,095 | - | 3 | - | $1,031 | $9,468 | 1 | N/A | true | false |
| 14 | 10 | The Golden Compass | $879 | -53% | 3 | -2 | $293 | $50,489 | 6 | N/A | false | false |
| 15 | 16 | Superbad | $695 | +124.9% | 3 | +2 | $231 | $38,624 | 7 | N/A | false | false |
| 16 | - | Lights in the Dusk | $580 | - | 1 | - | $580 | $1,626 | 1 | N/A | true | false |
| 17 | 11 | Bee Movie | $401 | -60% | 1 | -3 | $401 | $58,752 | 8 | N/A | false | false |
| 18 | 12 | Gone Baby Gone | $237 | -68.7% | 1 | -1 | $237 | $36,896 | 10 | N/A | false | false |
