| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | I Am Legend | $1,289,867 | +2.6% | 66 | - | $19,543 | $2,845,764 | 2 | Warner Bros. | false | false |
| 2 | 2 | Enchanted | $717,212 | +71.4% | 90 | -1 | $7,969 | $1,426,334 | 2 | Walt Disney Pictures | false | false |
| 3 | 3 | The Golden Compass | $643,667 | +62.6% | 150 | +45 | $4,291 | $2,408,515 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 4 | 4 | Bee Movie | $614,398 | +97.4% | 59 | -42 | $10,413 | $2,130,607 | 3 | Universal Pictures International (UPI) | false | false |
| 5 | 5 | Alvin and the Chipmunks | $523,201 | +215.5% | 71 | - | $7,369 | $765,697 | 2 | 20th Century Fox International | false | false |
| 6 | 7 | K3 en de kattenprins | $313,037 | +299.3% | 6 | -30 | $52,172 | $454,684 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 7 | - | Gone Baby Gone | $222,484 | - | 39 | - | $5,704 | $232,047 | 1 | Walt Disney Pictures | true | false |
| 8 | 6 | Elizabeth: The Golden Age | $182,728 | +40.9% | 37 | +1 | $4,938 | $679,162 | 3 | Universal Pictures International (UPI) | false | false |
| 9 | 11 | Good Luck Chuck | $133,214 | +115.2% | 11 | +1 | $12,110 | $235,537 | 2 | Sony Pictures Releasing | false | false |
| 10 | 9 | Hitman | $101,554 | +41% | 42 | - | $2,417 | $915,372 | 5 | 20th Century Fox International | false | false |
| 11 | - | Mr. Magorium's Wonder Emporium | $95,688 | - | 29 | - | $3,299 | $99,836 | 1 | Benelux Film Distributors | true | false |
| 12 | 8 | American Gangster | $88,907 | +21% | 30 | -12 | $2,963 | $2,014,699 | 7 | Universal Pictures International (UPI) | false | false |
| 13 | 10 | Beowulf | $87,239 | +31.1% | 20 | -13 | $4,361 | $1,429,584 | 6 | Warner Bros. | false | false |
| 14 | 12 | Eastern Promises | $75,556 | +30.9% | 21 | -4 | $3,597 | $642,638 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 15 | - | Cassandra's Dream | $65,225 | - | 17 | - | $3,836 | $105,651 | 1 | Cinéart | true | false |
| 16 | 16 | Two Worlds | $64,249 | +131.3% | 12 | -5 | $5,354 | $773,831 | 6 | Benelux Film Distributors | false | false |
| 17 | 13 | Missing Persons Unit | $62,366 | +58.6% | 22 | -2 | $2,834 | $1,867,228 | 9 | Kinepolis Film Distribution (KFD) | false | false |
| 18 | 14 | Cow-Boy | $46,972 | +25.6% | 21 | +1 | $2,236 | $310,129 | 4 | Belga Films | false | false |
| 19 | 19 | Surviving with Wolves | $46,550 | +75.6% | 25 | -4 | $1,862 | $484,475 | 6 | Victory Productions | false | false |
