| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Golden Compass | $817,866 | - | 110 | - | $7,435 | $842,057 | 1 | Warner Bros. | true | false |
| 2 | 1 | American Gangster | $201,874 | -25.7% | 52 | -5 | $3,882 | $1,847,566 | 4 | Universal Pictures International (UPI) | false | false |
| 3 | - | Why Men Don't Listen and Women Can't Read Maps | $131,877 | - | 21 | - | $6,279 | $137,406 | 1 | Rialto Distribution | true | false |
| 4 | 2 | Enchanted | $119,895 | -15.6% | 25 | +4 | $4,795 | $312,563 | 2 | Walt Disney Pictures | false | false |
| 5 | 3 | Ratatouille | $118,748 | -12.1% | 60 | -18 | $1,979 | $9,016,634 | 19 | Walt Disney Pictures | false | false |
| 6 | - | The Band's Visit | $85,525 | - | 12 | - | $7,127 | $95,078 | 1 | Xenix Filmdistribution | true | false |
| 7 | 5 | The Heartbreak Kid | $70,754 | -32.9% | 27 | -16 | $2,620 | $1,519,662 | 6 | Universal Pictures International (UPI) | false | false |
| 8 | 7 | Resident Evil: Extinction | $54,124 | -17.8% | 13 | - | $4,163 | $145,691 | 2 | Rialto Distribution | false | false |
| 9 | 6 | Lions for Lambs | $51,194 | -43.9% | 20 | -17 | $2,559 | $751,251 | 5 | 20th Century Fox International | false | false |
| 10 | 10 | Gone Baby Gone | $50,571 | +1.3% | 11 | - | $4,597 | $121,465 | 2 | Walt Disney Pictures | false | false |
| 11 | 9 | Earth | $46,800 | -14% | 26 | -5 | $1,800 | $1,058,483 | 9 | Frenetic Films | false | false |
| 12 | 4 | Beowulf | $43,487 | -59.8% | 30 | -23 | $1,449 | $686,002 | 4 | Warner Bros. | false | false |
| 13 | 8 | Atonement | $40,919 | -28.5% | 13 | -7 | $3,147 | $623,348 | 5 | Universal Pictures International (UPI) | false | false |
| 14 | 11 | The Three Investigators and the Secret of Skeleton Island | $33,518 | -26.8% | 45 | -14 | $744 | $433,431 | 5 | Walt Disney Pictures | false | false |
| 15 | 12 | I Now Pronounce You Chuck & Larry | $29,166 | -30.5% | 11 | -10 | $2,651 | $1,237,080 | 15 | Universal Pictures International (UPI) | false | false |
| 16 | 13 | Michael Clayton | $28,131 | -27.4% | 9 | -2 | $3,125 | $121,695 | 10 | Rialto Distribution | false | false |
| 17 | - | L'auberge rouge | $25,898 | - | 10 | - | $2,589 | $28,845 | 1 | JMH Distribution | true | false |
| 18 | 20 | My Blueberry Nights | $25,546 | +7.6% | 5 | +1 | $5,109 | $65,954 | 2 | Frenetic Films | false | false |
| 19 | 16 | Free Rainer | $25,449 | -16.8% | 8 | - | $3,181 | $73,269 | 2 | Pathé | false | false |
| 20 | - | Go West: A Lucky Luke Adventure | $22,194 | - | 10 | - | $2,219 | $22,834 | 1 | Pathé | true | false |
