| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Michael Clayton | $55,622 | -12.3% | 21 | - | $2,648 | $342,040 | 3 | Alfa Films | false | false |
| 2 | 2 | Underdog | $48,961 | -7.1% | 44 | - | $1,112 | $517,093 | 4 | Walt Disney Pictures | false | false |
| 3 | 3 | Resident Evil: Extinction | $42,628 | -18.5% | 30 | - | $1,420 | $319,236 | 3 | Sony Pictures Releasing | false | false |
| 4 | 4 | Knocked Up | $30,138 | -26.9% | 23 | - | $1,310 | $81,930 | 2 | United International Pictures | false | false |
| 5 | 6 | The Painted Veil | $28,380 | -4.1% | 20 | - | $1,419 | $240,100 | 4 | Distribution Company | false | false |
| 6 | 5 | Shoot 'Em Up | $28,153 | -27.6% | 30 | -6 | $938 | $80,485 | 2 | Distribution Company | false | false |
| 7 | 8 | Stardust | $26,235 | -3% | 29 | -1 | $904 | $154,546 | 3 | United International Pictures | false | false |
| 8 | 7 | La señal | $25,673 | -7.1% | 57 | +2 | $450 | $1,071,885 | 7 | Walt Disney Pictures | false | false |
| 9 | 9 | The Bourne Ultimatum | $23,261 | -11.4% | 43 | -2 | $540 | $1,216,889 | 9 | United International Pictures | false | false |
| 10 | 15 | Alpha Dog | $21,926 | +24.8% | 28 | - | $783 | $179,552 | 4 | Pachamama Cine | false | false |
| 11 | 10 | The Invasion | $21,184 | -2% | 28 | - | $756 | $224,458 | 4 | Warner Bros. | false | false |
| 12 | 11 | Premonition | $21,117 | +1.9% | 31 | +1 | $681 | $489,752 | 8 | Distribution Company | false | false |
| 13 | 14 | Next | $19,230 | +4.4% | 20 | - | $961 | $206,720 | 5 | United International Pictures | false | false |
| 14 | 13 | I Now Pronounce You Chuck & Larry | $18,419 | -3.4% | 30 | +2 | $613 | $287,027 | 6 | United International Pictures | false | false |
| 15 | 12 | License to Wed | $17,586 | -10.1% | 31 | +1 | $567 | $438,600 | 8 | Warner Bros. | false | false |
| 16 | 16 | Family Hero | $11,112 | -13% | 17 | - | $653 | $168,063 | 5 | Pachamama Cine | false | false |
| 17 | - | La mujer rota | $7,072 | - | 17 | - | $416 | $7,079 | 1 | Primer Plano Film Group | true | false |
| 18 | 17 | Black Book | $6,072 | -11.2% | 20 | -5 | $303 | $455,912 | 10 | Pachamama Cine | false | false |
| 19 | - | How I Celebrated the End of the World 2007 Re-release | $5,706 | - | 8 | - | $713 | $28,507 | 3 | Zeta Films | false | false |
| 20 | 19 | Surf's Up | $4,608 | -5.2% | 46 | - | $100 | $659,760 | 11 | Sony Pictures Releasing | false | false |
| 21 | 18 | Más que un hombre | $4,221 | -31.6% | 26 | -3 | $162 | $75,413 | 4 | Distribution Company | false | false |
| 22 | 30 | Flyboys | $3,470 | +112.8% | 17 | +2 | $204 | $39,634 | 5 | Distribution Company | false | false |
| 23 | - | Encarnacion | $2,733 | - | 9 | - | $303 | $31,994 | 3 | Distribution Company | false | false |
| 24 | 28 | In the Land of Women | $2,616 | +18.7% | 11 | +2 | $237 | $63,585 | 5 | CDI Films | false | false |
| 25 | 20 | The Invisible | $2,527 | -29.9% | 8 | -2 | $315 | $171,616 | 12 | Buena Vista International | false | false |
| 26 | 24 | Copying Beethoven | $2,439 | +0.5% | 11 | -2 | $221 | $194,093 | 10 | Alfa Films | false | false |
| 27 | - | Man to Man 2007 Re-release | $2,147 | - | 3 | - | $715 | $2,147 | 1 | Distribution Company | true | false |
| 28 | 22 | The Mudboy | $2,083 | -22% | 12 | - | $173 | $98,899 | 8 | Buena Vista International | false | false |
| 29 | 23 | Remember Me, My Love 2007 Re-release | $2,083 | -18.5% | 9 | -2 | $231 | $142,332 | 9 | CDI Films | false | false |
| 30 | 27 | Sicko | $1,751 | -21.8% | 9 | -1 | $194 | $61,522 | 6 | Alfa Films | false | false |
| 31 | 32 | Inland Empire | $1,477 | +4.8% | 5 | -1 | $295 | $72,037 | 7 | Distribution Company | false | false |
| 32 | 26 | Lights in the Dusk | $1,367 | -41.3% | 6 | - | $227 | $44,900 | 5 | Alfa Films | false | false |
| 33 | 21 | Seraphim Falls | $1,365 | -50.1% | 14 | -3 | $97 | $65,471 | 6 | Distribution Company | false | false |
| 34 | 25 | The Simpsons Movie | $1,268 | -46.2% | 14 | -8 | $90 | $7,308,132 | 14 | 20th Century Fox International | false | false |
| 35 | 39 | Touch the Sky | $1,103 | +221.6% | 6 | -7 | $183 | $485,762 | 12 | Sony Pictures Releasing | false | false |
| 36 | 31 | No Reservations | $1,078 | -24.6% | 15 | -5 | $71 | $485,878 | 11 | Warner Bros. | false | false |
| 37 | 33 | Live Free or Die Hard | $1,061 | -21.1% | 4 | -3 | $265 | $1,262,131 | 11 | 20th Century Fox International | false | false |
| 38 | 36 | Priceless | $812 | +17.5% | 8 | -1 | $101 | $136,780 | 8 | Alfa Films | false | false |
| 39 | 35 | Reincarnation | $719 | -2.7% | 7 | -2 | $102 | $188,847 | 15 | Pachamama Cine | false | false |
| 40 | 29 | ¿De quién es el portaligas? | $521 | -75.3% | 9 | -8 | $57 | $85,896 | 6 | Primer Plano Film Group | false | false |
| 41 | - | 28 Weeks Later | $365 | - | 4 | - | $91 | $221,176 | 21 | 20th Century Fox International | false | false |
| 42 | 34 | Hairspray | $333 | -66.5% | 5 | -4 | $66 | $577,533 | 12 | Distribution Company | false | false |
| 43 | 38 | Rush Hour 3 | $249 | -43.4% | 1 | -6 | $249 | $192,085 | 10 | Distribution Company | false | false |
| 44 | 41 | The Lives of Others | $247 | -0.8% | 1 | - | $247 | $990,786 | 28 | Alfa Films | false | false |
| 45 | 37 | XXY | $231 | -52.9% | 2 | -4 | $115 | $584,960 | 20 | Distribution Company | false | false |
| 46 | 43 | Kings & Queen 2006 Re-release | $178 | -6.3% | 2 | -2 | $89 | $22,970 | 10 | 791 Cine | false | false |
| 47 | 40 | Orchestra Seats | $156 | -38.6% | 1 | -1 | $156 | $315,272 | 20 | Alfa Films | false | false |
| 48 | 47 | Harry Potter and the Order of the Phoenix | $67 | +59.5% | 2 | +1 | $33 | $4,294,694 | 16 | Warner Bros. | false | false |
| 49 | - | Ocean's Thirteen | $64 | - | 2 | - | $32 | $1,243,581 | 13 | Warner Bros. | false | false |
| 50 | 44 | Stormbreaker | $63 | -54.7% | 3 | -7 | $21 | $92,886 | 7 | Impacto Cine | false | false |
| 51 | 42 | Ratatouille | $7 | -96.4% | 1 | -3 | $7 | $3,846,408 | 17 | Buena Vista International | false | false |
| 52 | 49 | Transformers | $7 | -80% | 1 | - | $7 | $2,611,053 | 15 | United International Pictures | false | false |
| 53 | 48 | Fantastic Four: Rise of the Silver Surfer | $3 | -91.4% | 1 | - | $3 | $1,200,044 | 18 | 20th Century Fox International | false | false |
