| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Simpsons Movie | $4,552,861 | -44.8% | 595 | -21 | $7,651 | $17,179,680 | 2 | 20th Century Fox International | false | false |
| 2 | 2 | Shrek the Third | $1,166,363 | -47.1% | 318 | -236 | $3,667 | $26,634,050 | 4 | Universal Pictures International (UPI) | false | false |
| 3 | - | Death at a Funeral | $793,117 | - | 218 | - | $3,638 | $869,545 | 1 | Mikado Film | true | false |
| 4 | - | Scrivilo sui muri | $641,882 | - | 290 | - | $2,213 | $645,109 | 1 | Eagle Pictures | true | false |
| 5 | 3 | The Last Legion | $557,946 | -31.1% | 226 | -27 | $2,468 | $1,756,471 | 2 | 01 Distribution | false | false |
| 6 | 5 | The Girl by the Lake | $532,178 | +3% | 133 | +8 | $4,001 | $1,387,518 | 2 | Medusa Distribuzione | false | false |
| 7 | - | Atonement | $528,563 | - | 217 | - | $2,435 | $528,563 | 1 | Universal Pictures International (UPI) | true | false |
| 8 | - | Superbad | $451,859 | - | 221 | - | $2,044 | $451,859 | 1 | Sony Pictures Releasing | true | false |
| 9 | 4 | No Reservations | $342,220 | -40.2% | 178 | -52 | $1,922 | $1,220,871 | 2 | Warner Bros. | false | false |
| 10 | - | Piano, solo | $285,109 | - | 117 | - | $2,436 | $285,109 | 1 | 01 Distribution | true | false |
| 11 | 6 | I Now Pronounce You Chuck & Larry | $229,190 | -53.9% | 110 | -86 | $2,083 | $2,017,077 | 3 | Universal Pictures International (UPI) | false | false |
| 12 | - | Severance | $172,910 | - | 122 | - | $1,417 | $172,910 | 1 | Medusa Distribuzione | true | false |
| 13 | 7 | Premonition | $95,301 | -75.2% | 44 | -156 | $2,165 | $1,581,262 | 3 | Eagle Pictures | false | false |
| 14 | 8 | Il dolce e l'amaro | $73,543 | -65% | 49 | -121 | $1,500 | $1,138,208 | 3 | Medusa Distribuzione | false | false |
| 15 | 9 | I'm Not There | $52,960 | -67.7% | 33 | -107 | $1,604 | $789,863 | 3 | BIM Distribuzione | false | false |
| 16 | 11 | Le ragioni dell'aragosta | $50,375 | -51.8% | 42 | -43 | $1,199 | $470,793 | 3 | Istituto Luce | false | false |
| 17 | 14 | Scream of the Ants | $25,975 | -33.7% | 14 | -2 | $1,855 | $86,602 | 2 | BIM Distribuzione | false | false |
| 18 | 16 | 4 Months, 3 Weeks and 2 Days | $25,578 | -20.2% | 19 | -1 | $1,346 | $779,810 | 5 | Lucky Red | false | false |
| 19 | 13 | Sicko | $21,037 | -57.4% | 14 | -20 | $1,502 | $1,861,579 | 5 | 01 Distribution | false | false |
| 20 | 10 | In the Land of Women | $17,387 | -85.7% | 17 | -75 | $1,022 | $2,819,548 | 5 | Moviemax | false | false |
| 21 | 23 | The Lives of Others | $15,716 | +32.7% | 8 | +3 | $1,964 | $5,062,400 | 25 | 01 Distribution | false | false |
| 22 | 21 | The Romance of Astrea and Celadon | $13,395 | -26.1% | 11 | -1 | $1,217 | $135,018 | 4 | BIM Distribuzione | false | false |
| 23 | 19 | Harry Potter and the Order of the Phoenix | $9,666 | -57.1% | 12 | -20 | $805 | $26,221,771 | 11 | Warner Bros. | false | false |
| 24 | 22 | Breath | $9,476 | -42% | 8 | -1 | $1,184 | $163,855 | 4 | Mikado Film | false | false |
| 25 | 15 | The Trial Begins | $7,567 | -77.6% | 9 | -48 | $840 | $182,561 | 3 | 01 Distribution | false | false |
| 26 | 26 | The Wind Blows Round | $7,525 | +79.9% | 4 | - | $1,881 | $234,319 | 21 | Aranciafilm | false | false |
| 27 | 17 | License to Wed | $5,177 | -81.3% | 6 | -22 | $862 | $1,667,294 | 5 | Warner Bros. | false | false |
| 28 | 12 | Captivity | $3,658 | -96.1% | 4 | -67 | $914 | $1,738,305 | 4 | Filmauro | false | false |
| 29 | - | Shan: The Ancient Heart of Natural People | $2,924 | - | 4 | - | $731 | $114,289 | 27 | N/A | false | false |
| 30 | 24 | Pathfinder | $2,645 | -62.6% | 5 | -10 | $529 | $1,533,420 | 5 | 20th Century Fox International | false | false |
| 31 | 32 | The Duchess of Langeais | $1,892 | +2.9% | 3 | +2 | $630 | $187,502 | 11 | Mikado Film | false | false |
| 32 | 29 | Le ferie di Licu | $1,572 | -41.1% | 2 | -1 | $786 | $102,164 | 21 | Independent Films | false | false |
| 33 | 36 | The Reef | $1,445 | +15.5% | 2 | -1 | $722 | $357,708 | 12 | Mediafilm | false | false |
| 34 | 31 | Tuya's Marriage | $1,403 | -30.5% | 1 | -2 | $1,403 | $758,239 | 16 | Lucky Red | false | false |
| 35 | - | La Vie En Rose | $1,390 | - | 2 | - | $695 | $1,340,834 | 21 | Mikado Film | false | false |
| 36 | 44 | One Hundred Nails | $1,206 | +165.1% | 1 | - | $1,206 | $3,404,025 | 26 | Mikado Film | false | false |
| 37 | 49 | As the Shadow | $1,018 | +356.5% | 1 | - | $1,018 | $150,300 | 14 | Istituto Luce | false | false |
| 38 | 33 | Sweet Sweet Marja | $983 | -44.5% | 1 | - | $983 | $61,820 | 9 | Mediaplex | false | false |
| 39 | - | John Tucker Must Die | $938 | - | 1 | - | $938 | $807,239 | 10 | 20th Century Fox International | false | false |
| 40 | 28 | XXY | $896 | -71.4% | 1 | -3 | $896 | $414,481 | 14 | Teodora Film | false | false |
| 41 | - | Fast Food Nation | $758 | - | 2 | - | $379 | $138,314 | 10 | DNC Entertainment | false | false |
| 42 | 37 | Don't Make Any Plans for Tonight | $648 | -31.9% | 1 | - | $648 | $41,993 | 15 | Independent Films | false | false |
| 43 | 34 | Four Minutes | $624 | -60.2% | 2 | - | $312 | $1,046,846 | 21 | Lady Film | false | false |
| 44 | 30 | My Brother is an Only Child | $552 | -77.5% | 1 | -2 | $552 | $8,927,733 | 23 | Warner Bros. | false | false |
| 45 | 47 | The Magic Flute | $537 | +33.6% | 1 | - | $537 | $89,849 | 13 | 01 Distribution | false | false |
| 46 | 38 | Ocean's Thirteen | $500 | -39.2% | 2 | - | $250 | $8,079,131 | 16 | Warner Bros. | false | false |
| 47 | 42 | Fantastic Four: Rise of the Silver Surfer | $454 | -34.8% | 1 | - | $454 | $9,761,172 | 15 | 20th Century Fox International | false | false |
| 48 | 35 | Prova a volare | $447 | -69.4% | 2 | -4 | $223 | $436,700 | 5 | Istituto Luce | false | false |
| 49 | 20 | Black Christmas | $437 | -97.8% | 3 | -25 | $145 | $36,281 | 2 | Mediafilm | false | false |
| 50 | - | Transylvania | $425 | - | 2 | - | $212 | $11,303 | 5 | Lady Film | false | false |
