| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Pirates of the Caribbean: At World's End | $1,936,266 | -34.8% | 180 | +2 | $10,757 | $7,178,436 | 2 | Buena Vista International | false | false |
| 2 | 2 | Spider-Man 3 | $108,818 | -55.5% | 103 | -3 | $1,056 | $4,021,725 | 5 | Sony Pictures Releasing | false | false |
| 3 | 3 | Fracture | $103,909 | -41.2% | 51 | - | $2,037 | $771,634 | 3 | RCV Film Distribution | false | false |
| 4 | - | Zodiac | $84,098 | - | 19 | - | $4,426 | $84,098 | 1 | Warner Bros. | true | false |
| 5 | 4 | Mr. Bean's Holiday | $77,953 | -50.2% | 100 | -1 | $779 | $6,222,830 | 10 | Universal Pictures International (UPI) | false | false |
| 6 | - | The Messengers | $63,255 | - | 20 | - | $3,162 | $85,516 | 1 | Benelux Film Distributors | true | false |
| 7 | 5 | The Reef | $47,804 | -54.8% | 85 | - | $562 | $593,878 | 3 | Independent Films | false | false |
| 8 | 6 | The Number 23 | $44,799 | -47.2% | 24 | - | $1,866 | $380,415 | 3 | Paradiso Entertainment | false | false |
| 9 | 7 | Next | $44,420 | -47.3% | 65 | -3 | $683 | $1,049,738 | 6 | RCV Film Distribution | false | false |
| 10 | 9 | The Lives of Others | $38,165 | -37.1% | 29 | -2 | $1,316 | $1,779,017 | 14 | Cinemien | false | false |
| 11 | 10 | Pan's Labyrinth | $29,158 | -43.2% | 21 | - | $1,388 | $537,397 | 6 | Paradiso Entertainment | false | false |
| 12 | 8 | The Reaping | $25,990 | -58.6% | 31 | - | $838 | $469,032 | 4 | Warner Bros. | false | false |
| 13 | 11 | Perfect Stranger | $14,720 | -63.5% | 23 | -4 | $640 | $766,195 | 8 | Sony Pictures Releasing | false | false |
| 14 | 14 | The Hoax | $14,658 | -43.5% | 15 | - | $977 | $84,823 | 2 | Independent Films | false | false |
| 15 | 12 | Wild Hogs | $13,487 | -63.2% | 40 | -10 | $337 | $1,321,587 | 8 | Buena Vista International | false | false |
| 16 | 13 | Happily N'Ever After | $13,281 | -54.4% | 66 | - | $201 | $390,678 | 6 | Independent Films | false | false |
| 17 | 15 | Dark Blue Almost Black | $12,354 | -35.2% | 5 | - | $2,470 | $77,004 | 3 | A-Film Distribution | false | false |
| 18 | 16 | TMNT | $10,219 | -43.2% | 72 | -5 | $141 | $360,524 | 7 | Warner Bros. | false | false |
| 19 | - | Black Snake Moan | $9,130 | - | 5 | - | $1,826 | $28,362 | 1 | Universal Pictures International (UPI) | true | false |
| 20 | - | La Vie En Rose | $8,054 | - | 24 | - | $335 | $664,513 | 13 | RCV Film Distribution | false | false |
| 21 | - | Exiles 2007 Re-release | $471 | - | 1 | - | $471 | $471 | 1 | A-Film Distribution | true | false |
