| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Pirates of the Caribbean: At World's End | $5,236,512 | -46.9% | 604 | -2 | $8,669 | $17,605,163 | 2 | Buena Vista International | false | false |
| 2 | 2 | Spider-Man 3 | $676,121 | -28.4% | 376 | -32 | $1,798 | $18,784,847 | 5 | Sony Pictures Releasing | false | false |
| 3 | 3 | Zodiac | $485,743 | -9.4% | 182 | - | $2,668 | $2,508,700 | 3 | Roadshow Entertainment | false | false |
| 4 | - | Romulus, My Father | $275,641 | - | 45 | - | $6,125 | $275,641 | 1 | Dendy Films | true | false |
| 5 | 4 | Georgia Rule | $260,739 | -4.7% | 167 | - | $1,561 | $2,072,026 | 4 | Hoyts Distribution | false | false |
| 6 | 5 | Breach | $227,911 | -3.2% | 90 | -2 | $2,532 | $1,003,756 | 3 | Rialto Distribution | false | false |
| 7 | 6 | Because I Said So | $191,253 | -9.8% | 133 | -22 | $1,437 | $2,847,997 | 5 | Magna Pacific | false | false |
| 8 | 7 | 28 Weeks Later | $156,936 | -12.8% | 114 | -41 | $1,376 | $1,850,556 | 4 | 20th Century Fox International | false | false |
| 9 | 8 | Off the Grid | $121,312 | +43.3% | 3 | +1 | $40,437 | $218,499 | 2 | Warren Miller Entertainment | false | false |
| 10 | - | Bridge to Terabithia | $71,358 | - | 65 | - | $1,097 | $88,590 | - | Buena Vista International | - | false |
| 11 | 10 | My Best Friend | $69,689 | -6.4% | 18 | - | $3,871 | $291,834 | 2 | Hopscotch Films | false | false |
| 12 | 9 | The History Boys | $61,062 | -21% | 49 | -5 | $1,246 | $959,647 | 5 | 20th Century Fox International | false | false |
| 13 | 17 | As It Is in Heaven | $58,506 | +55.6% | 19 | +4 | $3,079 | $992,270 | 44 | Rialto Distribution | false | false |
| 14 | 11 | Shooter | $56,361 | -14.7% | 55 | -13 | $1,024 | $4,433,765 | 7 | Paramount Pictures International | false | false |
| 15 | 13 | Noise | $54,220 | -8.7% | 20 | +3 | $2,711 | $465,605 | 5 | Madman Entertainment | false | false |
| 16 | 15 | The Italian | $48,438 | -5.3% | 11 | +3 | $4,403 | $445,845 | 6 | Sharmill Films | false | false |
| 17 | 12 | The Lives of Others | $48,070 | -21.9% | 34 | +1 | $1,413 | $1,855,780 | 10 | Hopscotch Films | false | false |
| 18 | 16 | Paris, Je T'aime | $45,062 | -9.2% | 31 | +3 | $1,453 | $1,049,086 | 7 | Madman Entertainment | false | false |
| 19 | 14 | Reno 911!: Miami | $34,722 | -39.8% | 45 | -41 | $771 | $340,117 | 3 | Paramount Pictures International | false | false |
| 20 | - | Orchestra Seats | $31,305 | - | 12 | - | $2,608 | $122,669 | 1 | Rialto Distribution | true | false |
| 21 | - | The Messengers | $30,641 | - | 41 | - | $747 | $30,641 | 1 | Roadshow Films | true | false |
| 22 | - | The Last Mimzy | $21,998 | - | 41 | - | $536 | $21,998 | 1 | Roadshow Films | true | false |
| 23 | - | The U.S. vs. John Lennon | $17,315 | - | 2 | - | $8,657 | $17,315 | 1 | Roadshow Films | true | false |
| 24 | - | End of the Spear | $5,441 | - | 8 | - | $680 | $5,441 | 1 | Con Dios Entertainment | true | false |
