| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Night at the Museum | $199,150 | -14.9% | 76 | -1 | $2,620 | $3,177,635 | 5 | 20th Century Fox International | false | false |
| 2 | 2 | Apocalypto | $174,720 | -17.9% | 53 | - | $3,296 | $470,981 | 2 | AF-Media | false | false |
| 3 | 3 | Firmin | $137,892 | -11.3% | 25 | +2 | $5,515 | $1,503,397 | 5 | N/A | false | false |
| 4 | 5 | The Number 23 | $118,124 | -20.5% | 23 | - | $5,135 | $556,531 | 3 | Paradiso Entertainment | false | false |
| 5 | 4 | Taxi 4 | $109,026 | -26.9% | 42 | -5 | $2,595 | $2,357,336 | 5 | Belga Films | false | false |
| 6 | 7 | La Vie En Rose | $100,281 | -15.7% | 25 | - | $4,011 | $1,236,345 | 5 | Cinéart | false | false |
| 7 | - | Freedom Writers | $88,516 | - | 15 | - | $5,901 | $91,526 | 1 | Universal Pictures International (UPI) | true | false |
| 8 | 6 | Ghost Rider | $79,609 | -36.4% | 30 | - | $2,653 | $847,615 | 4 | Sony Pictures Releasing | false | false |
| 9 | 17 | Barnyard | $66,122 | +25.1% | 31 | - | $2,132 | $510,896 | 4 | Universal Pictures International (UPI) | false | false |
| 10 | 12 | The Lives of Others | $63,826 | +3.1% | 13 | +1 | $4,909 | $669,792 | 7 | ABC Distribution | false | false |
| 11 | 8 | Dreamgirls | $63,396 | -45.7% | 33 | -2 | $1,921 | $541,864 | 3 | Universal Pictures International (UPI) | false | false |
| 12 | 19 | Charlotte's Web | $59,847 | +27.6% | 58 | - | $1,031 | $1,041,610 | 6 | Universal Pictures International (UPI) | false | false |
| 13 | 11 | The Departed | $56,240 | -9.3% | 18 | -10 | $3,124 | $3,557,061 | 12 | Warner Bros. | false | false |
| 14 | 15 | Dance with Him | $56,004 | +1.6% | 11 | - | $5,091 | $123,502 | 2 | Victory Productions | false | false |
| 15 | - | Crank | $55,677 | - | 9 | - | $6,186 | $55,924 | 1 | Paradiso Entertainment | true | false |
| 16 | - | Man of the Year | $54,543 | - | 11 | - | $4,958 | $61,321 | 1 | Benelux Film Distributors | true | false |
| 17 | 9 | Hannibal Rising | $49,580 | -38.7% | 34 | -6 | $1,458 | $686,039 | 4 | Benelux Film Distributors | false | false |
| 18 | 13 | The Painted Veil | $42,539 | -31.2% | 17 | -3 | $2,502 | $125,561 | 2 | Belga Films | false | false |
| 19 | 10 | Blood Diamond | $38,518 | -44.7% | 27 | -8 | $1,426 | $2,218,337 | 8 | Warner Bros. | false | false |
| 20 | - | Angel | $4,892 | - | 21 | - | $232 | $49,642 | 1 | ABC Distribution | true | false |
