| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Pursuit of Happyness | $263,963 | - | 51 | - | $5,175 | $263,963 | 1 | Sony Pictures Releasing | true | false |
| 2 | - | Epic Movie | $241,469 | - | 40 | - | $6,036 | $241,469 | 1 | 20th Century Fox International | true | false |
| 3 | 1 | Blood Diamond | $140,886 | -23.2% | 43 | - | $3,276 | $413,783 | 2 | Warner Bros. | false | false |
| 4 | 2 | Happy Feet | $106,548 | -31.3% | 75 | -13 | $1,420 | $2,673,894 | 5 | Roadshow Films | false | false |
| 5 | 5 | Open Season | $101,497 | -24.4% | 67 | -3 | $1,514 | $700,591 | 3 | Sony Pictures Releasing | false | false |
| 6 | 4 | Casino Royale | $94,646 | -30.4% | 70 | -9 | $1,352 | $3,847,837 | 8 | Sony Pictures Releasing | false | false |
| 7 | 8 | The Queen | $82,743 | -16% | 58 | +6 | $1,426 | $1,194,878 | 6 | Icon Film Distribution | false | false |
| 8 | 6 | Night at the Museum | $73,866 | -32.6% | 63 | - | $1,172 | $1,667,759 | 5 | 20th Century Fox International | false | false |
| 9 | 3 | Dreamgirls | $73,432 | -48.5% | 35 | - | $2,098 | $281,322 | 2 | Paramount Pictures International | false | false |
| 10 | 7 | Apocalypto | $59,946 | -43.8% | 32 | -3 | $1,873 | $490,934 | 3 | Hoyts Distribution | false | false |
| 11 | 11 | Babel | $40,117 | -11.7% | 15 | +1 | $2,674 | $284,018 | 4 | United International Pictures | false | false |
| 12 | 12 | Arthur and the Invisibles | $36,794 | -16.7% | 34 | - | $1,082 | $120,383 | 2 | Roadshow Films | false | false |
| 13 | - | The History Boys | $36,739 | - | 10 | - | $3,673 | $36,739 | 1 | 20th Century Fox International | true | false |
| 14 | 13 | Borat | $29,599 | -21.9% | 34 | -4 | $870 | $2,268,434 | 10 | 20th Century Fox International | false | false |
| 15 | 15 | The Valet | $21,007 | -32.5% | 17 | +1 | $1,235 | $381,073 | 6 | Rialto Distribution | false | false |
| 16 | 16 | Flicka | $19,617 | -24.2% | 49 | -6 | $400 | $69,845 | 2 | 20th Century Fox International | false | false |
| 17 | 17 | Charlotte's Web | $19,090 | -25.1% | 46 | -4 | $415 | $623,032 | 6 | United International Pictures | false | false |
| 18 | 20 | Volver | $18,284 | -18.3% | 13 | +4 | $1,406 | $50,997 | 2 | Dendy Films | false | false |
| 19 | 10 | The Prestige | $17,044 | -63.3% | 35 | -5 | $486 | $550,422 | 4 | Warner Bros. | false | false |
| 20 | 9 | Saw III | $16,052 | -66.3% | 20 | -16 | $802 | $475,329 | 4 | Hoyts Distribution | false | false |
