| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Pursuit of Happyness | $2,009,355 | -35.7% | 517 | +5 | $3,886 | $5,788,898 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Blood Diamond | $1,640,943 | - | 493 | - | $3,328 | $1,640,943 | 1 | Warner Bros. | true | false |
| 3 | - | Arthur and the Invisibles | $1,068,606 | - | 494 | - | $2,163 | $1,068,606 | 1 | TOBIS Film | true | false |
| 4 | 5 | The Other Boy | $650,597 | -31.3% | 250 | - | $2,602 | $1,789,141 | 2 | Constantin Film | false | false |
| 5 | 3 | My Führer | $648,309 | -49.8% | 390 | +1 | $1,662 | $5,340,649 | 3 | X Verleih AG | false | false |
| 6 | - | One Way | $618,961 | - | 304 | - | $2,036 | $618,961 | 1 | Universal Pictures International (UPI) | true | false |
| 7 | 9 | Babel | $465,570 | -12.4% | 114 | +1 | $4,083 | $4,761,756 | 6 | TOBIS Film | false | false |
| 8 | 2 | Night at the Museum | $405,205 | -75.9% | 554 | -253 | $731 | $19,896,305 | 5 | 20th Century Fox International | false | false |
| 9 | 6 | Deja Vu | $395,602 | -44.8% | 453 | -142 | $873 | $10,414,399 | 5 | Buena Vista International | false | false |
| 10 | 7 | The Holiday | $390,661 | -35.5% | 438 | -97 | $891 | $15,196,491 | 7 | United International Pictures | false | false |
| 11 | 8 | Casino Royale | $381,118 | -36.9% | 314 | -99 | $1,213 | $48,831,079 | 10 | Sony Pictures Releasing | false | false |
| 12 | 10 | The Queen | $357,911 | -26% | 153 | - | $2,339 | $1,999,582 | 3 | Concorde Filmverleih | false | false |
| 13 | 4 | John Tucker Must Die | $350,734 | -72.1% | 291 | -111 | $1,205 | $1,830,352 | 2 | 20th Century Fox International | false | false |
| 14 | - | The Masked Gang: Iraq | $253,684 | - | 53 | - | $4,786 | $253,684 | 1 | Maxximum Film und Kunst GmbH | true | false |
| 15 | - | Paris, Je T'aime | $234,247 | - | 71 | - | $3,299 | $234,247 | 1 | Senator Film | true | false |
