| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Happy Feet | $308,525 | +0.2% | 88 | +1 | $3,505 | $2,147,770 | 3 | Roadshow Films | false | false |
| 2 | - | Open Season | $237,055 | - | 71 | - | $3,338 | $237,055 | 1 | Sony Pictures Releasing | true | false |
| 3 | 2 | Casino Royale | $229,164 | +3.3% | 79 | +3 | $2,900 | $3,458,112 | 6 | Sony Pictures Releasing | false | false |
| 4 | - | Apocalypto | $211,099 | - | 33 | - | $6,396 | $211,099 | 1 | Hoyts Distribution | true | false |
| 5 | 3 | Night at the Museum | $207,737 | -5.6% | 62 | -14 | $3,350 | $1,308,892 | 3 | 20th Century Fox International | false | false |
| 6 | 5 | The Queen | $143,226 | +1.5% | 54 | - | $2,652 | $869,446 | 4 | Icon Film Distribution | false | false |
| 7 | 6 | The Prestige | $104,763 | -12.8% | 39 | +1 | $2,686 | $420,848 | 2 | Warner Bros. | false | false |
| 8 | 4 | Saw III | $98,287 | -45.2% | 36 | +3 | $2,730 | $354,943 | 2 | Hoyts Distribution | false | false |
| 9 | 7 | Deja Vu | $82,059 | -16.4% | 41 | -5 | $2,001 | $733,879 | 4 | Buena Vista International | false | false |
| 10 | 11 | Babel | $62,061 | +18.2% | 14 | - | $4,432 | $149,287 | 2 | United International Pictures | false | false |
| 11 | 8 | Eragon | $58,625 | -29.4% | 63 | -5 | $930 | $1,077,204 | 5 | 20th Century Fox International | false | false |
| 12 | 10 | Charlotte's Web | $55,910 | +1.9% | 57 | -3 | $980 | $519,825 | 4 | United International Pictures | false | false |
| 13 | 12 | The Valet | $53,750 | +28.7% | 15 | - | $3,583 | $294,444 | 4 | Rialto Distribution | false | false |
| 14 | 13 | Borat | $53,688 | +47.4% | 40 | +2 | $1,342 | $2,154,421 | 8 | 20th Century Fox International | false | false |
| 15 | 9 | The Holiday | $52,510 | -22.7% | 37 | -9 | $1,419 | $858,210 | 5 | United International Pictures | false | false |
| 16 | - | Marie Antoinette | $19,872 | - | 14 | - | $1,419 | $168,007 | - | Sony Pictures Releasing | - | false |
| 17 | 15 | Flushed Away | $18,159 | -17.4% | 36 | -4 | $504 | $589,400 | 6 | United International Pictures | false | false |
| 18 | 16 | Little Miss Sunshine | $17,622 | +83.7% | 17 | +7 | $1,036 | $632,832 | 14 | 20th Century Fox International | false | false |
| 19 | - | Four Last Songs | $12,119 | - | 13 | - | $932 | $12,119 | 1 | Rialto Distribution | true | false |
| 20 | 19 | The White Massai | $6,773 | +66.2% | 10 | +1 | $677 | $192,557 | 11 | Hopscotch Films | false | false |
