| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Eragon | $4,095,738 | - | 495 | - | $8,274 | $4,095,738 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Happy Feet | $1,027,952 | -62.9% | 473 | -7 | $2,173 | $5,828,005 | 2 | Warner Bros. | false | false |
| 3 | 2 | Deja Vu | $951,770 | -54.4% | 401 | -7 | $2,373 | $7,594,519 | 3 | Buena Vista International | false | false |
| 4 | - | Arthur and the Invisibles | $797,580 | - | 377 | - | $2,115 | $797,580 | 1 | New World Pictures | true | false |
| 5 | 5 | The Holiday | $741,602 | -52% | 291 | -4 | $2,548 | $3,555,169 | 2 | United International Pictures | false | false |
| 6 | 7 | The Illusionist | $645,100 | -47.7% | 206 | - | $3,131 | $7,433,333 | 5 | - | false | false |
| 7 | 6 | Perfume: The Story of a Murderer | $570,334 | -56% | 296 | -12 | $1,926 | $7,678,847 | 4 | Filmax | false | false |
| 8 | 3 | Flushed Away | $552,367 | -69.8% | 391 | -48 | $1,412 | $5,963,776 | 3 | United International Pictures | false | false |
| 9 | 4 | Casino Royale | $493,612 | -68.3% | 291 | -187 | $1,696 | $10,344,007 | 4 | Sony Pictures Releasing | false | false |
| 10 | - | Unaccompanied Minors | $285,079 | - | 198 | - | $1,439 | $285,079 | 1 | Warner Bros. | true | false |
| 11 | 8 | Isi/Disi: Alto voltaje | $159,182 | -73.7% | 235 | -62 | $677 | $2,194,607 | 3 | Azteca Films | false | false |
| 12 | 9 | Summer Rain | $153,929 | -71.2% | 247 | -42 | $623 | $2,039,154 | 3 | 20th Century Fox International | false | false |
| 13 | 13 | Scoop | $114,060 | -49.6% | 96 | -13 | $1,188 | $6,960,535 | 8 | On Pictures | false | false |
| 14 | 10 | The Departed | $111,143 | -57.6% | 79 | -48 | $1,406 | $11,415,929 | 8 | Warner Bros. | false | false |
| 15 | - | Mia Sarah | $104,321 | - | 88 | - | $1,185 | $118,970 | 1 | Filmax | true | false |
| 16 | - | Family Law | $88,183 | - | 32 | - | $2,755 | $88,183 | 1 | - | true | false |
| 17 | 11 | The Nativity Story | $66,136 | -74.4% | 170 | -50 | $389 | $836,678 | 3 | TriPictures | false | false |
| 18 | - | Could This Be Love? | $62,519 | - | 44 | - | $1,420 | $62,519 | 1 | Eurocine | true | false |
| 19 | 17 | Little Miss Sunshine | $51,203 | -42.8% | 26 | -8 | $1,969 | $2,660,350 | 9 | 20th Century Fox International | false | false |
| 20 | 19 | Into Great Silence | $50,437 | -33.7% | 15 | - | $3,362 | $394,585 | 4 | Karma Films | false | false |
