| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Eragon | $3,876,068 | - | 781 | - | $4,962 | $3,876,068 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Casino Royale | $3,095,355 | -40.7% | 801 | -55 | $3,864 | $35,592,127 | 4 | Sony Pictures Releasing | false | false |
| 3 | - | The Holiday | $2,617,962 | - | 542 | - | $4,830 | $2,617,962 | 1 | United International Pictures | true | false |
| 4 | 2 | The Departed | $1,444,684 | -37.3% | 432 | -2 | $3,344 | $4,461,501 | 2 | Warner Bros. | false | false |
| 5 | 4 | Happy Feet | $907,065 | -28.2% | 692 | +29 | $1,310 | $4,397,448 | 3 | Warner Bros. | false | false |
| 6 | 3 | Flushed Away | $815,603 | -39.6% | 688 | -3 | $1,185 | $2,298,287 | 2 | United International Pictures | false | false |
| 7 | - | Apocalypto | $478,366 | - | 202 | - | $2,368 | $478,366 | 1 | Constantin Film | true | false |
| 8 | 5 | Wo ist Fred? | $285,729 | -50.1% | 348 | -109 | $821 | $5,825,877 | 5 | Senator Film | false | false |
| 9 | 8 | Little Miss Sunshine | $205,746 | -32.6% | 123 | +14 | $1,672 | $1,139,715 | 3 | 20th Century Fox International | false | false |
| 10 | 7 | 7 Dwarves: The Forest Is Not Enough | $192,868 | -44.6% | 346 | -149 | $557 | $25,147,054 | 8 | United International Pictures | false | false |
| 11 | 6 | Borat | $176,267 | -58% | 296 | -98 | $595 | $13,217,490 | 7 | 20th Century Fox International | false | false |
| 12 | 10 | Pettson & Findus: The Santa Machine | $170,223 | +7% | 291 | -3 | $584 | $1,699,309 | 7 | MFA+ FilmDistribution | false | false |
| 13 | 11 | Grave Decisions | $134,407 | -13% | 90 | -5 | $1,493 | $9,456,449 | 18 | Movienet | false | false |
| 14 | 9 | Open Season | $126,713 | -44.1% | 422 | -239 | $300 | $5,626,331 | 6 | Sony Pictures Releasing | false | false |
| 15 | 12 | Scoop | $87,127 | -39% | 95 | - | $917 | $1,740,035 | 5 | Concorde Filmverleih | false | false |
