| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Departed | $264,726 | - | 63 | - | $4,202 | $264,726 | 1 | Warner Bros. | true | false |
| 2 | - | The Santa Clause 3: The Escape Clause | $126,415 | - | 37 | - | $3,416 | $126,415 | 1 | Buena Vista International | true | false |
| 3 | - | Borat | $115,611 | - | 20 | - | $5,780 | $115,611 | - | 20th Century Fox International | - | false |
| 4 | 1 | Jackass Number Two | $96,916 | -32.5% | 47 | +1 | $2,062 | $526,623 | 3 | United International Pictures | false | false |
| 5 | 2 | A Good Year | $94,652 | -32.8% | 60 | - | $1,577 | $283,203 | 2 | 20th Century Fox International | false | false |
| 6 | 3 | The Devil Wears Prada | $73,847 | -19.9% | 60 | -6 | $1,230 | $1,195,271 | 5 | 20th Century Fox International | false | false |
| 7 | 4 | Kenny | $68,641 | +7.5% | 25 | +4 | $2,745 | $156,555 | 2 | Madman Entertainment | false | false |
| 8 | 7 | Out of the Blue | $38,783 | -11.8% | 33 | +1 | $1,175 | $608,561 | 6 | Dendy Films | false | false |
| 9 | 8 | Little Miss Sunshine | $32,539 | -13.6% | 22 | - | $1,479 | $462,773 | 6 | 20th Century Fox International | false | false |
| 10 | - | Beyond the Sea | $29,851 | - | 19 | - | $1,571 | $29,851 | 1 | Arkles Entertainment | true | false |
| 11 | 6 | The Grudge 2 | $25,688 | -51.5% | 25 | -7 | $1,027 | $323,223 | 4 | Roadshow Films | false | false |
| 12 | 5 | Flags of Our Fathers | $25,202 | -54.2% | 44 | +1 | $572 | $204,140 | 3 | Warner Bros. | false | false |
| 13 | 10 | An Inconvenient Truth | $20,759 | +7% | 20 | -3 | $1,037 | $608,367 | 10 | United International Pictures | false | false |
| 14 | 11 | The Wind that Shakes the Barley | $17,450 | -7.7% | 15 | +1 | $1,163 | $158,690 | 4 | Dendy Films | false | false |
| 15 | 12 | The White Massai | $12,458 | -9.9% | 14 | +1 | $889 | $114,456 | 3 | Hopscotch Films | false | false |
| 16 | 17 | Mrs Palfrey at the Claremont | $10,074 | +25.6% | 18 | -1 | $559 | $1,137,544 | 14 | Rialto Distribution | false | false |
| 17 | - | As It Is in Heaven | $8,411 | - | 9 | - | $934 | $543,577 | 47 | Rialto Distribution | false | false |
| 18 | 20 | Manual of Love | $7,197 | +6.8% | 2 | - | $3,598 | $16,243 | 2 | - | false | false |
| 19 | 9 | The Guardian | $6,977 | -66.3% | 18 | -17 | $387 | $314,957 | 5 | Buena Vista International | false | false |
| 20 | 16 | Sophie Scholl: The Final Days | $6,397 | -22.7% | 11 | -3 | $581 | $30,764 | 3 | - | false | false |
