| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Departed | $363,812 | - | 76 | - | $4,787 | $363,812 | 1 | Warner Bros. | true | false |
| 2 | 1 | Saw III | $107,977 | -31.7% | 48 | - | $2,249 | $698,524 | 3 | Buena Vista International | false | false |
| 3 | 2 | The Illusionist | $84,944 | -15.4% | 29 | - | $2,929 | $729,257 | 5 | Alfa Films | false | false |
| 4 | 6 | Open Season | $30,396 | +3.9% | 48 | -4 | $633 | $462,711 | 7 | Sony Pictures Releasing | false | false |
| 5 | 3 | The Devil Wears Prada | $28,020 | -21.8% | 34 | - | $824 | $855,101 | 9 | 20th Century Fox International | false | false |
| 6 | 12 | Barnyard | $26,009 | +42.8% | 32 | - | $812 | $262,179 | 6 | United International Pictures | false | false |
| 7 | 7 | World Trade Center | $25,895 | -9.6% | 40 | - | $647 | $321,420 | 5 | United International Pictures | false | false |
| 8 | 8 | You, Me and Dupree | $25,408 | -3.9% | 30 | - | $846 | $478,030 | 8 | United International Pictures | false | false |
| 9 | 11 | Pulse | $19,070 | -2.7% | 25 | +1 | $762 | $257,950 | 6 | Distribution Company | false | false |
| 10 | 9 | The Guardian | $18,800 | -25% | 45 | -2 | $417 | $447,334 | 7 | Buena Vista International | false | false |
| 11 | 4 | Sophie Scholl: The Final Days | $17,747 | -48.6% | 11 | - | $1,613 | $60,365 | 2 | Alfa Films | false | false |
| 12 | 10 | The Covenant | $16,972 | -27.1% | 29 | - | $585 | $154,215 | 4 | Sony Pictures Releasing | false | false |
| 13 | 5 | All the King's Men | $13,375 | -58% | 12 | - | $1,114 | $53,135 | 2 | Sony Pictures Releasing | false | false |
| 14 | 17 | Little Miss Sunshine | $9,016 | -25.3% | 13 | - | $693 | $152,401 | 6 | 20th Century Fox International | false | false |
| 15 | 15 | Keeping Mum | $8,520 | -38.4% | 9 | - | $946 | $51,421 | 3 | Distribution Company | false | false |
| 16 | 16 | Heading South | $8,263 | -38.6% | 13 | - | $635 | $110,239 | 4 | Pachamama Cine | false | false |
| 17 | 14 | Hard Candy | $7,701 | -48% | 7 | - | $1,100 | $26,878 | 2 | Distribution Company | false | false |
| 18 | - | Chicha tu madre | $6,909 | - | 5 | - | $1,381 | $6,909 | 1 | Distribution Company | true | false |
| 19 | 20 | Click | $6,627 | -11.5% | 21 | -6 | $315 | $690,622 | 14 | Sony Pictures Releasing | false | false |
| 20 | 19 | Thank You for Smoking | $5,728 | -27.8% | 13 | -1 | $440 | $70,181 | 4 | 20th Century Fox International | false | false |
