| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Saw III | $305,978 | - | 49 | - | $6,244 | $305,978 | 1 | Buena Vista International | true | false |
| 2 | 1 | The Illusionist | $138,878 | -6.8% | 29 | - | $4,788 | $482,085 | 3 | Alfa Films | false | false |
| 3 | 4 | Open Season | $56,558 | +2.4% | 51 | +2 | $1,108 | $417,286 | 5 | Sony Pictures Releasing | false | false |
| 4 | 3 | The Devil Wears Prada | $54,475 | -2.3% | 35 | - | $1,556 | $767,163 | 7 | 20th Century Fox International | false | false |
| 5 | 2 | World Trade Center | $49,770 | -26.4% | 40 | - | $1,244 | $246,604 | 3 | United International Pictures | false | false |
| 6 | 6 | Barnyard | $38,102 | -20.1% | 32 | - | $1,190 | $205,665 | 4 | United International Pictures | false | false |
| 7 | 9 | You, Me and Dupree | $38,024 | -7.8% | 30 | - | $1,267 | $410,006 | 6 | United International Pictures | false | false |
| 8 | 8 | The Guardian | $35,796 | -15.5% | 47 | - | $761 | $387,508 | 5 | Buena Vista International | false | false |
| 9 | 5 | The Covenant | $33,594 | -37.7% | 29 | - | $1,158 | $99,804 | 2 | Sony Pictures Releasing | false | false |
| 10 | 7 | Heading South | $26,653 | -38.3% | 13 | - | $2,050 | $78,837 | 2 | Pachamama Cine | false | false |
| 11 | 10 | Pulse | $22,958 | -30.9% | 24 | -1 | $956 | $207,813 | 4 | Distribution Company | false | false |
| 12 | - | Keeping Mum | $22,227 | - | 6 | - | $3,704 | $22,227 | 1 | Distribution Company | true | false |
| 13 | 11 | The Lake House | $21,013 | -22.6% | 26 | -1 | $808 | $695,250 | 10 | Warner Bros. | false | false |
| 14 | 12 | Thank You for Smoking | $17,192 | -36.2% | 12 | - | $1,432 | $50,098 | 2 | 20th Century Fox International | false | false |
| 15 | 15 | Little Miss Sunshine | $16,979 | -17.4% | 13 | - | $1,306 | $123,802 | 4 | 20th Century Fox International | false | false |
| 16 | 14 | Cheese Head | $13,753 | -39.7% | 20 | - | $687 | $135,048 | 4 | Primer Plano Film Group | false | false |
| 17 | 13 | Born and Bred | $12,313 | -51% | 13 | - | $947 | $43,375 | 2 | Distribution Company | false | false |
| 18 | 17 | Click | $9,563 | -34.1% | 27 | -4 | $354 | $670,317 | 12 | Sony Pictures Releasing | false | false |
| 19 | - | Friends with Money | $9,559 | - | 13 | - | $735 | $78,205 | 4 | Sony Pictures Releasing | false | false |
| 20 | - | The Wind that Shakes the Barley | $8,330 | - | 12 | - | $694 | $118,625 | 5 | Distribution Company | false | false |
