| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Saw III | $4,786,567 | - | 373 | - | $12,832 | $4,786,567 | 1 | Lionsgate | true | false |
| 2 | - | Step Up | $2,301,186 | - | 307 | - | $7,495 | $2,301,186 | 1 | United International Pictures | true | false |
| 3 | 1 | The Departed | $1,966,366 | -28.3% | 376 | +18 | $5,229 | $19,269,146 | 4 | Entertainment Film Distributors | false | false |
| 4 | 4 | Open Season | $1,841,277 | -3.6% | 448 | +1 | $4,109 | $11,105,972 | 3 | Sony Pictures Releasing | false | false |
| 5 | 2 | The Devil Wears Prada | $1,708,953 | -33.2% | 439 | -9 | $3,892 | $22,123,471 | 4 | 20th Century Fox International | false | false |
| 6 | 3 | Barnyard | $1,410,175 | -26.8% | 446 | +2 | $3,161 | $5,666,082 | 2 | United International Pictures | false | false |
| 7 | 8 | Click | $806,628 | -29.7% | 303 | -57 | $2,662 | $13,829,488 | 5 | Sony Pictures Releasing | false | false |
| 8 | 7 | The History Boys | $796,732 | -33.8% | 235 | -65 | $3,390 | $5,699,190 | 3 | 20th Century Fox International | false | false |
| 9 | - | A Good Year | $715,298 | - | 276 | - | $2,591 | $715,298 | 1 | 20th Century Fox International | true | false |
| 10 | 9 | Hoodwinked! | $679,167 | +1.8% | 433 | -29 | $1,568 | $10,077,672 | 5 | Momentum Pictures | false | false |
| 11 | 6 | The Grudge 2 | $660,203 | -54.7% | 328 | -3 | $2,012 | $3,249,004 | 2 | United International Pictures | false | false |
| 12 | 5 | The Guardian | $638,290 | -59% | 338 | -17 | $1,888 | $3,218,205 | 2 | Buena Vista International | false | false |
| 13 | 10 | Don | $552,442 | +0.7% | 52 | +1 | $10,623 | $1,958,979 | 2 | UTV Motion Pictures | false | false |
| 14 | 11 | Marie Antoinette | $253,491 | -52.6% | 122 | -57 | $2,077 | $1,217,393 | 2 | Sony Pictures Releasing | false | false |
| 15 | 14 | The Queen | $200,296 | -34.3% | 125 | -63 | $1,602 | $13,533,332 | 7 | Pathé | false | false |
| 16 | 17 | Jaan-E-Mann: Lets Fall in Love Again | $171,082 | +38.6% | 35 | -7 | $4,888 | $658,639 | 2 | Adlabs Films | false | false |
| 17 | - | Red Road | $155,583 | - | 38 | - | $4,094 | $155,583 | 1 | Verve Pictures | true | false |
| 18 | - | All the King's Men | $92,378 | - | 101 | - | $914 | $92,378 | 1 | Sony Pictures Releasing | true | false |
| 19 | 16 | Little Miss Sunshine | $85,288 | -34.4% | 36 | -13 | $2,369 | $5,726,972 | 8 | 20th Century Fox International | false | false |
| 20 | 13 | World Trade Center | $82,915 | -75.9% | 85 | -143 | $975 | $9,031,127 | 5 | United International Pictures | false | false |
| 21 | 18 | Stick It | $79,539 | -15.7% | 19 | -175 | $4,186 | $701,207 | 3 | Buena Vista International | false | false |
| 22 | 12 | The Texas Chainsaw Massacre: The Beginning | $74,309 | -85.5% | 132 | -154 | $562 | $2,790,803 | 3 | Entertainment Film Distributors | false | false |
| 23 | 15 | Children of Men | $70,121 | -59.9% | 374 | +290 | $187 | $8,998,110 | 6 | United International Pictures | false | false |
| 24 | - | The Magician | $34,704 | - | 4 | - | $8,676 | $34,704 | 1 | Diva | true | false |
| 25 | - | Vallavan | $33,877 | - | 3 | - | $11,292 | $33,877 | 1 | Ayngaran International | true | false |
| 26 | 27 | Monster House | $29,850 | +61.5% | 63 | -4 | $473 | $12,418,875 | 12 | Sony Pictures Releasing | false | false |
| 27 | 22 | Stormbreaker | $27,829 | -15.1% | 60 | -96 | $463 | $12,872,046 | 15 | Entertainment Film Distributors | false | false |
| 28 | 25 | Over the Hedge | $22,822 | -1.4% | 72 | -1 | $316 | $24,732,156 | 18 | United International Pictures | false | false |
| 29 | 24 | An Inconvenient Truth | $17,440 | -33.2% | 14 | -7 | $1,245 | $1,331,814 | 7 | United International Pictures | false | false |
| 30 | 20 | Volver | $12,746 | -76.8% | 8 | -12 | $1,593 | $5,081,983 | 10 | Pathé | false | false |
| 31 | 19 | Accepted | $11,448 | -79.9% | 17 | -45 | $673 | $1,368,118 | 4 | United International Pictures | false | false |
| 32 | 28 | Cars | $8,871 | -29.5% | 21 | -17 | $422 | $30,858,370 | 14 | Buena Vista International | false | false |
| 33 | 29 | I Saw Ben Barka Get Killed | $8,156 | -28% | 2 | -1 | $4,078 | $28,727 | 2 | Artificial Eye | false | false |
| 34 | 31 | Zidane - A 21st Century Portrait | $6,928 | -18.2% | 6 | - | $1,154 | $68,797 | 5 | Artificial Eye | false | false |
| 35 | 23 | Varalaaru | $5,469 | -79.5% | 3 | - | $1,823 | $53,121 | 2 | Ayngaran International | false | false |
| 36 | 37 | The Ant Bully | $5,015 | +23.1% | 17 | -2 | $295 | $3,752,639 | 13 | Warner Bros. | false | false |
| 37 | - | Havoc | $4,362 | - | 10 | - | $436 | $4,362 | 1 | The Works UK Distribution | true | false |
| 38 | 49 | Driving Lessons | $4,165 | +127.3% | 5 | +2 | $833 | $267,598 | 8 | Tartan | false | false |
| 39 | 36 | Leonard Cohen: I'm Your Man | $3,207 | -31.9% | 2 | -1 | $1,603 | $12,038 | 2 | Lionsgate | false | false |
| 40 | 39 | Snow Cake | $3,106 | -8.5% | 3 | -2 | $1,035 | $180,224 | 8 | Momentum Pictures | false | false |
| 41 | - | Exam | $2,854 | - | 1 | - | $2,854 | $2,854 | 1 | Maxximum Film und Kunst GmbH | true | false |
| 42 | 30 | Gypo | $2,524 | -77% | 4 | -3 | $631 | $18,909 | 2 | Lionsgate | false | false |
| 43 | 35 | Pirates of the Caribbean: Dead Man's Chest | $2,203 | -54.2% | 8 | +6 | $275 | $98,668,102 | 17 | Buena Vista International | false | false |
| 44 | 34 | Neil Young: Heart of Gold | $2,150 | -57.8% | 2 | -1 | $1,075 | $50,254 | 4 | United International Pictures | false | false |
| 45 | 42 | Quinceañera | $2,127 | -11.4% | 5 | - | $425 | $66,429 | 5 | - | false | false |
| 46 | 33 | A Scanner Darkly | $1,810 | -68.3% | 3 | -1 | $603 | $1,778,192 | 11 | Warner Bros. | false | false |
| 47 | - | The Pervert's Guide to Cinema | $1,526 | - | 1 | - | $1,526 | $9,633 | 4 | ICA Films | false | false |
| 48 | - | Frozen Land 2006 Re-release | $1,241 | - | 1 | - | $1,241 | $7,664 | 3 | ICA Films | false | false |
| 49 | 50 | Nina's Heavenly Delights | $1,237 | -24.4% | 1 | -1 | $1,237 | $40,235 | 5 | Verve Pictures | false | false |
| 50 | - | Snuff-Movie | $1,142 | - | 2 | - | $571 | $1,142 | 1 | Lionsgate | true | false |
