| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Departed | $2,381,580 | - | 375 | - | $6,350 | $2,381,580 | 1 | Warner Bros. | true | false |
| 2 | - | Scoop | $1,172,989 | - | 159 | - | $7,377 | $1,172,989 | 1 | On Pictures | true | false |
| 3 | 1 | Pan's Labyrinth | $946,545 | -29.2% | 302 | +1 | $3,134 | $6,279,931 | 3 | Warner Bros. | false | false |
| 4 | - | Nobody Is Perfect | $898,673 | - | 201 | - | $4,471 | $898,673 | 1 | Sony Pictures Releasing | true | false |
| 5 | 2 | The Black Dahlia | $668,977 | -44.3% | 240 | +1 | $2,787 | $2,259,284 | 2 | TriPictures | false | false |
| 6 | - | Barnyard | $651,346 | - | 220 | - | $2,960 | $651,346 | 1 | United International Pictures | true | false |
| 7 | 5 | My Name Is Juani | $629,648 | -25.4% | 186 | +1 | $3,385 | $1,700,018 | 2 | Manga Entertainment | false | false |
| 8 | 4 | The Borgia | $592,985 | -33% | 294 | -28 | $2,016 | $6,854,025 | 4 | DeAPlaneta | false | false |
| 9 | 3 | The Devil Wears Prada | $561,739 | -36.7% | 292 | -10 | $1,923 | $7,040,995 | 4 | 20th Century Fox International | false | false |
| 10 | 6 | Children of Men | $425,734 | -28.6% | 156 | - | $2,729 | $1,214,691 | 2 | United International Pictures | false | false |
| 11 | 9 | Little Miss Sunshine | $368,711 | -13.5% | 163 | -16 | $2,262 | $933,081 | 2 | 20th Century Fox International | false | false |
| 12 | 7 | The Guardian | $207,566 | -58.4% | 287 | -115 | $723 | $2,776,020 | 3 | Buena Vista International | false | false |
| 13 | 8 | The Wicker Man | $200,397 | -58.5% | 247 | -4 | $811 | $818,561 | 2 | Filmax | false | false |
| 14 | 13 | Copying Beethoven | $190,036 | -18.7% | 87 | -4 | $2,184 | $532,470 | 2 | Notro Films | false | false |
| 15 | 11 | Click | $141,545 | -53.8% | 129 | -111 | $1,097 | $5,214,473 | 5 | Sony Pictures Releasing | false | false |
| 16 | - | Them | $122,673 | - | 74 | - | $1,657 | $122,673 | 1 | Vértigo Films | true | false |
| 17 | 10 | You, Me and Dupree | $107,502 | -65.1% | 140 | -59 | $767 | $1,546,575 | 3 | United International Pictures | false | false |
| 18 | 14 | Hoodwinked! | $95,387 | -55.6% | 136 | -32 | $701 | $3,771,724 | 6 | Manga Entertainment | false | false |
| 19 | 12 | Crank | $88,647 | -64.8% | 126 | -127 | $703 | $1,607,281 | 3 | Aurum Films | false | false |
| 20 | 15 | World Trade Center | $66,710 | -59.7% | 114 | -70 | $585 | $5,800,013 | 5 | United International Pictures | false | false |
