| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Devil Wears Prada | $1,879,408 | -28.2% | 321 | -2 | $5,854 | $7,019,918 | 3 | 20th Century Fox International | false | false |
| 2 | 2 | Step Up | $850,147 | -33.9% | 154 | - | $5,520 | $2,765,754 | 2 | United International Pictures | false | false |
| 3 | - | World Trade Center | $682,662 | - | 203 | - | $3,362 | $682,662 | 1 | United International Pictures | true | false |
| 4 | 5 | Garfield: A Tail of Two Kitties | $682,490 | +18.2% | 203 | -1 | $3,362 | $3,557,086 | 5 | 20th Century Fox International | false | false |
| 5 | 4 | Monster House | $634,388 | -1.6% | 261 | -5 | $2,430 | $4,376,249 | 4 | Sony Pictures Releasing | false | false |
| 6 | 3 | Talladega Nights: The Ballad of Ricky Bobby | $523,034 | -31.6% | 250 | -2,640 | $2,092 | $3,609,254 | 3 | Sony Pictures Releasing | false | false |
| 7 | 7 | The Wild | $463,869 | +31.6% | 254 | +1 | $1,826 | $1,873,316 | 2 | Buena Vista International | false | false |
| 8 | 6 | Barnyard | $442,792 | +8.5% | 196 | -9 | $2,259 | $2,236,152 | 3 | United International Pictures | false | false |
| 9 | 8 | The Ant Bully | $282,278 | +12.9% | 198 | -13 | $1,425 | $1,240,947 | 2 | Warner Bros. | false | false |
| 10 | 12 | Kenny | $251,759 | +28.8% | 111 | +13 | $2,268 | $3,390,249 | 8 | Madman Entertainment | false | false |
| 11 | 9 | Stormbreaker | $221,774 | -1.9% | 174 | -5 | $1,274 | $1,460,882 | 3 | Roadshow Films | false | false |
| 12 | - | Little Miss Sunshine | $210,152 | - | 109 | - | $1,928 | $223,135 | 1 | Park Circus | true | false |
| 13 | 10 | An Inconvenient Truth | $187,140 | -15.2% | 58 | - | $3,226 | $1,712,345 | 4 | United International Pictures | false | false |
| 14 | 11 | Nacho Libre | $129,517 | -39.3% | 168 | -52 | $770 | $2,248,823 | 4 | United International Pictures | false | false |
| 15 | - | A Prairie Home Companion | $114,348 | - | 31 | - | $3,688 | $115,095 | 1 | Hoyts Distribution | true | false |
| 16 | 13 | John Tucker Must Die | $96,554 | -33.2% | 100 | -33 | $965 | $2,682,828 | 5 | 20th Century Fox International | false | false |
| 17 | 14 | Beerfest | $90,804 | -25.7% | 95 | -6 | $955 | $291,347 | 2 | Warner Bros. | false | false |
| 18 | 15 | Material Girls | $87,884 | -25.7% | 94 | -33 | $934 | $1,175,576 | 4 | Hoyts Distribution | false | false |
| 19 | 16 | The Wind that Shakes the Barley | $64,199 | -20.6% | 26 | +1 | $2,469 | $396,227 | 3 | Dendy Films | false | false |
| 20 | 17 | Aquamarine | $48,365 | -6.4% | 78 | -3 | $620 | $141,851 | 2 | 20th Century Fox International | false | false |
