| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Talladega Nights: The Ballad of Ricky Bobby | $140,030 | - | 53 | - | $2,642 | $140,030 | 1 | Sony Pictures Releasing | true | false |
| 2 | 2 | Garfield: A Tail of Two Kitties | $105,110 | -38.6% | 79 | +1 | $1,330 | $302,116 | 2 | 20th Century Fox International | false | false |
| 3 | - | John Tucker Must Die | $85,302 | - | 34 | - | $2,508 | $85,302 | 1 | 20th Century Fox International | true | false |
| 4 | - | Stormbreaker | $84,236 | - | 45 | - | $1,871 | $84,236 | 1 | Roadshow Films | true | false |
| 5 | 1 | Nacho Libre | $79,329 | -54.1% | 50 | -1 | $1,586 | $299,108 | 2 | United International Pictures | false | false |
| 6 | 3 | Stick It | $66,030 | -43% | 31 | +1 | $2,130 | $212,413 | 2 | Roadshow Films | false | false |
| 7 | 4 | Mrs Palfrey at the Claremont | $64,786 | -24.1% | 37 | -4 | $1,750 | $809,268 | 6 | Rialto Distribution | false | false |
| 8 | - | Monster House | $53,088 | - | 63 | - | $842 | $107,703 | 1 | Sony Pictures Releasing | true | false |
| 9 | 5 | An Inconvenient Truth | $50,059 | -7.8% | 11 | +1 | $4,550 | $189,044 | 2 | United International Pictures | false | false |
| 10 | - | Barnyard | $38,980 | - | 50 | - | $779 | $38,980 | 1 | United International Pictures | true | false |
| 11 | - | The Wild | $34,961 | - | 41 | - | $852 | $52,844 | 1 | Buena Vista International | true | false |
| 12 | 7 | Wah-Wah | $34,369 | -13.3% | 18 | +7 | $1,909 | $182,046 | 3 | Hopscotch Films | false | false |
| 13 | - | Water 2006 Re-release | $30,822 | - | 12 | - | $2,568 | $78,198 | 1 | Dendy Films | true | false |
| 14 | 11 | Thank You for Smoking | $17,550 | -35.1% | 10 | - | $1,755 | $240,876 | 5 | 20th Century Fox International | false | false |
| 15 | - | The Ant Bully | $16,493 | - | 50 | - | $329 | $16,493 | 1 | Warner Bros. | true | false |
| 16 | 6 | Little Man | $11,099 | -76.6% | 24 | -19 | $462 | $400,175 | 4 | Sony Pictures Releasing | false | false |
| 17 | 8 | Silent Hill | $10,452 | -70.1% | 14 | -14 | $746 | $249,643 | 4 | United International Pictures | false | false |
| 18 | 9 | Lady in the Water | $9,912 | -71% | 21 | -23 | $472 | $148,963 | 3 | Warner Bros. | false | false |
| 19 | 20 | As It Is in Heaven | $9,822 | +6.8% | 12 | -1 | $818 | $454,602 | 39 | Rialto Distribution | false | false |
| 20 | 16 | These Foolish Things | $9,275 | -38.3% | 10 | - | $927 | $26,629 | 2 | - | false | false |
