| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Captain Alatriste: The Spanish Musketeer | $1,593,853 | -34.8% | 443 | -7 | $3,597 | $18,243,361 | 4 | 20th Century Fox International | false | false |
| 2 | 2 | Little Man | $1,432,432 | -30.5% | 250 | - | $5,729 | $3,936,575 | 2 | Sony Pictures Releasing | false | false |
| 3 | - | Hoodwinked! | $1,139,740 | - | 256 | - | $4,452 | $1,139,740 | 1 | Manga Entertainment | true | false |
| 4 | 3 | The Break-Up | $967,214 | -28% | 228 | +1 | $4,242 | $2,706,075 | 2 | United International Pictures | false | false |
| 5 | - | My Super Ex-Girlfriend | $931,745 | - | 298 | - | $3,126 | $931,745 | 1 | 20th Century Fox International | true | false |
| 6 | 5 | Salvador | $610,506 | -16.3% | 189 | - | $3,230 | $1,665,292 | 2 | Warner Bros. | false | false |
| 7 | 4 | Miami Vice | $496,086 | -38.1% | 283 | -9 | $1,752 | $3,811,443 | 3 | United International Pictures | false | false |
| 8 | - | The Lazarus Child | $415,959 | - | 145 | - | $2,868 | $415,959 | 1 | Aurum Films | true | false |
| 9 | - | La máquina de bailar | $409,970 | - | 249 | - | $1,646 | $409,970 | 1 | United International Pictures | true | false |
| 10 | 6 | Monster House | $389,158 | -32.2% | 286 | -57 | $1,360 | $4,419,103 | 4 | Sony Pictures Releasing | false | false |
| 11 | 10 | The Wind that Shakes the Barley | $298,996 | -15.9% | 109 | - | $2,743 | $806,537 | 2 | Alta Films | false | false |
| 12 | 7 | Pirates of the Caribbean: Dead Man's Chest | $280,413 | -43.9% | 227 | -129 | $1,235 | $36,276,589 | 7 | Buena Vista International | false | false |
| 13 | 8 | The Ant Bully | $277,189 | -34.2% | 257 | -8 | $1,078 | $1,674,585 | 3 | Warner Bros. | false | false |
| 14 | 9 | Garfield: A Tail of Two Kitties | $230,060 | -44.1% | 257 | -84 | $895 | $8,192,322 | 5 | 20th Century Fox International | false | false |
| 15 | 12 | United 93 | $187,265 | -29.2% | 116 | -14 | $1,614 | $3,378,732 | 5 | United International Pictures | false | false |
| 16 | 11 | Lady in the Water | $146,833 | -55.8% | 145 | -142 | $1,012 | $5,595,899 | 5 | Warner Bros. | false | false |
| 17 | - | Nine Lives | $104,822 | - | 18 | - | $5,823 | $104,822 | 1 | Versus Entertainment | true | false |
| 18 | 15 | The Night of the Sunflowers | $99,594 | -18.5% | 82 | -8 | $1,214 | $1,123,189 | 5 | Alta Films | false | false |
| 19 | 13 | Edison | $96,678 | -42.4% | 89 | -47 | $1,086 | $1,512,402 | 4 | Filmax | false | false |
| 20 | - | Thank You for Smoking | $91,021 | - | 64 | - | $1,422 | $91,021 | 1 | 20th Century Fox International | true | false |
