| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Devil Wears Prada | $185,044 | - | 36 | - | $5,140 | $185,044 | 1 | 20th Century Fox International | true | false |
| 2 | 2 | Snakes on a Plane | $64,024 | -11.1% | 48 | +2 | $1,333 | $154,377 | 2 | Distribution Company | false | false |
| 3 | 1 | Miami Vice | $61,546 | -19.3% | 50 | - | $1,230 | $329,778 | 3 | United International Pictures | false | false |
| 4 | 3 | The Lake House | $52,116 | -19.2% | 28 | +1 | $1,861 | $441,326 | 4 | Warner Bros. | false | false |
| 5 | 6 | Click | $45,676 | +19.9% | 31 | - | $1,473 | $514,265 | 6 | Sony Pictures Releasing | false | false |
| 6 | 4 | Volver | $40,887 | -7.5% | 31 | +1 | $1,318 | $765,843 | 7 | 20th Century Fox International | false | false |
| 7 | 7 | Transamerica | $34,057 | -2.1% | 18 | +7 | $1,892 | $79,264 | 2 | Alfa Films | false | false |
| 8 | 10 | Lady in the Water | $31,358 | +17% | 24 | - | $1,306 | $306,694 | 5 | Warner Bros. | false | false |
| 9 | 8 | The Jacket | $28,141 | -0.3% | 28 | - | $1,005 | $130,951 | 3 | Alfa Films | false | false |
| 10 | 14 | Monster House | $26,285 | +31.6% | 47 | -1 | $559 | $496,925 | 7 | Sony Pictures Releasing | false | false |
| 11 | 5 | Fuerza aérea sociedad anónima | $25,003 | -35.7% | 18 | -1 | $1,389 | $261,827 | 4 | Distribution Company | false | false |
| 12 | 9 | The Break-Up | $21,810 | -19.3% | 40 | - | $545 | $905,570 | 8 | United International Pictures | false | false |
| 13 | 12 | The Sentinel | $21,685 | -12.8% | 38 | -1 | $570 | $506,355 | 6 | 20th Century Fox International | false | false |
| 14 | 11 | United 93 | $21,254 | -14.6% | 20 | - | $1,062 | $221,460 | 4 | United International Pictures | false | false |
| 15 | 15 | My Super Ex-Girlfriend | $17,260 | -11.8% | 21 | -2 | $821 | $99,466 | 3 | 20th Century Fox International | false | false |
| 16 | 17 | 16 Blocks | $16,356 | -9.3% | 31 | +1 | $527 | $503,778 | 7 | Distribution Company | false | false |
| 17 | 13 | The Hands | $15,064 | -31.2% | 43 | -3 | $350 | $494,371 | 7 | Primer Plano Film Group | false | false |
| 18 | - | The Ant Bully | $12,570 | - | 30 | - | $419 | $179,878 | 6 | Warner Bros. | false | false |
| 19 | 19 | The Fast and the Furious: Tokyo Drift | $12,436 | +15.7% | 30 | +1 | $414 | $265,559 | 6 | United International Pictures | false | false |
| 20 | 18 | Pirates of the Caribbean: Dead Man's Chest | $11,445 | -14.7% | 27 | -1 | $423 | $4,353,664 | 10 | Buena Vista International | false | false |
