| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | John Tucker Must Die | $795,831 | - | 177 | - | $4,496 | $795,831 | 1 | 20th Century Fox International | true | false |
| 2 | - | Lady in the Water | $436,534 | - | 232 | - | $1,881 | $436,534 | 1 | Warner Bros. | true | false |
| 3 | 3 | Kenny | $398,097 | +12.5% | 97 | +7 | $4,104 | $1,770,590 | 4 | Madman Entertainment | false | false |
| 4 | - | DOA: Dead or Alive | $395,612 | - | 139 | - | $2,846 | $395,612 | 1 | United International Pictures | true | false |
| 5 | 1 | Silent Hill | $328,345 | -42.2% | 155 | +16 | $2,118 | $1,082,228 | 2 | United International Pictures | false | false |
| 6 | 8 | Friends with Money | $279,645 | -1.9% | 44 | - | $6,355 | $681,725 | 2 | Roadshow Films | false | false |
| 7 | 4 | Thank You for Smoking | $269,763 | -17.8% | 90 | +1 | $2,997 | $1,474,947 | 3 | 20th Century Fox International | false | false |
| 8 | 2 | Snakes on a Plane | $262,948 | -41.4% | 206 | -19 | $1,276 | $1,856,125 | 3 | Roadshow Films | false | false |
| 9 | 5 | You, Me and Dupree | $223,078 | -31.3% | 163 | -16 | $1,368 | $7,361,734 | 7 | United International Pictures | false | false |
| 10 | 9 | Hoodwinked! | $221,152 | -21.1% | 188 | -8 | $1,176 | $3,876,475 | 6 | Roadshow Films | false | false |
| 11 | 11 | Pirates of the Caribbean: Dead Man's Chest | $189,077 | -28.5% | 151 | -42 | $1,252 | $28,197,153 | 10 | Buena Vista International | false | false |
| 12 | 6 | Clerks II | $170,842 | -46.8% | 124 | - | $1,377 | $608,997 | 2 | Roadshow Films | false | false |
| 13 | - | Garfield: A Tail of Two Kitties | $161,091 | - | 60 | - | $2,684 | $164,410 | 1 | 20th Century Fox International | true | false |
| 14 | 7 | Miami Vice | $152,079 | -49.4% | 145 | +121 | $1,048 | $4,946,923 | 5 | United International Pictures | false | false |
| 15 | 10 | Fearless | $139,836 | -48.3% | 125 | -15 | $1,118 | $1,213,440 | 3 | United International Pictures | false | false |
| 16 | 13 | Jindabyne | $121,792 | -16.6% | 86 | - | $1,416 | $3,459,664 | 8 | Roadshow Films | false | false |
| 17 | - | An Inconvenient Truth | $104,334 | - | 59 | - | $1,768 | $106,768 | - | United International Pictures | - | false |
| 18 | - | Stormbreaker | $98,425 | - | 59 | - | $1,668 | $98,425 | - | Roadshow Films | - | false |
| 19 | 14 | Curious George | $79,766 | -40.9% | 109 | -82 | $731 | $814,828 | 4 | United International Pictures | false | false |
| 20 | 12 | United 93 | $75,783 | -50.6% | 92 | -84 | $823 | $1,295,286 | 4 | United International Pictures | false | false |
