| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Pirates of the Caribbean: Dead Man's Chest | $25,422,357 | - | 512 | - | $49,653 | $25,422,357 | 1 | Buena Vista International | true | false |
| 2 | 1 | Over the Hedge | $4,010,945 | -39.5% | 501 | -3 | $8,005 | $12,864,955 | 2 | United International Pictures | false | false |
| 3 | 2 | Just My Luck | $785,265 | -26.6% | 326 | +1 | $2,408 | $2,534,823 | 2 | 20th Century Fox International | false | false |
| 4 | 3 | The Fast and the Furious: Tokyo Drift | $614,411 | -38.4% | 355 | -53 | $1,730 | $9,793,674 | 4 | United International Pictures | false | false |
| 5 | 5 | The Wind that Shakes the Barley | $497,954 | -20.1% | 106 | +1 | $4,697 | $3,215,014 | 3 | Pathé | false | false |
| 6 | 4 | The Lake House | $458,620 | -37.6% | 287 | -55 | $1,597 | $4,387,704 | 3 | Warner Bros. | false | false |
| 7 | 6 | The Da Vinci Code | $225,439 | -47.4% | 140 | -169 | $1,610 | $55,419,388 | 8 | Sony Pictures Releasing | false | false |
| 8 | - | District B13 | $182,696 | - | 71 | - | $2,573 | $182,696 | 1 | Momentum Pictures | true | false |
| 9 | 7 | X-Men: The Last Stand | $162,039 | -62.1% | 171 | -130 | $947 | $35,103,765 | 7 | 20th Century Fox International | false | false |
| 10 | 12 | Krrish | $111,645 | -45.8% | 33 | -12 | $3,383 | $1,021,121 | 3 | Adlabs Films | false | false |
| 11 | 8 | Fearless | $100,818 | -71.5% | 101 | -144 | $998 | $1,909,700 | 3 | United International Pictures | false | false |
| 12 | 13 | Thank You for Smoking | $89,056 | -45.8% | 53 | -42 | $1,680 | $1,568,640 | 4 | 20th Century Fox International | false | false |
| 13 | 9 | Hard Candy | $66,620 | -74% | 91 | -122 | $732 | $3,197,080 | 4 | Lionsgate | false | false |
| 14 | - | Heading South | $66,211 | - | 15 | - | $4,414 | $66,211 | 1 | Soda Pictures | true | false |
| 15 | 11 | Reeker | $61,110 | -70.5% | 87 | -16 | $702 | $432,302 | 2 | Pathé | false | false |
| 16 | 14 | United 93 | $49,147 | -55.8% | 49 | -75 | $1,003 | $4,978,037 | 6 | United International Pictures | false | false |
| 17 | 10 | The Omen | $45,636 | -80.4% | 70 | -164 | $651 | $7,992,265 | 5 | 20th Century Fox International | false | false |
| 18 | - | Ju-On: The Grudge 2 2006 Re-release | $27,456 | - | 17 | - | $1,615 | $27,456 | 1 | Contender Entertainment Group | true | false |
| 19 | - | Deep Sea | $25,256 | - | 1 | - | $25,256 | $783,097 | 19 | IMAX | false | false |
| 20 | 15 | Poseidon | $22,969 | -75.2% | 23 | -66 | $998 | $6,765,134 | 6 | Warner Bros. | false | false |
| 21 | 20 | The Wild | $22,209 | -37.8% | 80 | -102 | $277 | $7,905,493 | 7 | Buena Vista International | false | false |
| 22 | - | Chup Chup Ke | $21,639 | - | 14 | - | $1,545 | $580,396 | 5 | UTV Motion Pictures | false | false |
| 23 | 19 | Phir Hera Pheri | $21,051 | -42.1% | 15 | -6 | $1,403 | $848,786 | 5 | - | false | false |
| 24 | - | Corporate | $19,254 | - | 12 | - | $1,604 | $19,254 | 1 | - | true | false |
| 25 | - | Little Manhattan | $18,666 | - | 62 | - | $301 | $18,666 | 1 | 20th Century Fox International | true | false |
| 26 | 22 | The Cave of the Yellow Dog | $16,675 | -28.5% | 14 | -3 | $1,191 | $69,499 | 2 | Tartan | false | false |
| 27 | - | Curious George | $15,569 | - | 63 | - | $247 | $2,640,599 | 7 | United International Pictures | false | false |
| 28 | - | Awesome; I Shot That! | $15,145 | - | 5 | - | $3,029 | $15,145 | 1 | Revolver Entertainment | true | false |
| 29 | 17 | RV | $15,108 | -75.5% | 55 | -131 | $274 | $1,935,845 | 5 | Sony Pictures Releasing | false | false |
| 30 | - | Friends with Money | $11,206 | - | 7 | - | $1,600 | $754,307 | 7 | Sony Pictures Releasing | false | false |
| 31 | 21 | Dave Chappelle's Block Party | $10,466 | -66% | 15 | -5 | $697 | $65,835 | 2 | Optimum Releasing | false | false |
| 32 | 18 | Aquamarine | $10,340 | -77% | 39 | -113 | $265 | $394,167 | 3 | 20th Century Fox International | false | false |
| 33 | - | Fanaa | $9,469 | - | 7 | - | $1,352 | $2,157,367 | 7 | Yash Raj Films | false | false |
| 34 | 23 | Forty Shades of Blue | $9,278 | -26.8% | 6 | -1 | $1,546 | $32,172 | 2 | Artificial Eye | false | false |
| 35 | 27 | Rebecca 2006 Re-release | $9,256 | +242.7% | 2 | - | $4,628 | $23,223 | 2 | British Film Institute (BFI) | false | false |
| 36 | - | Quai des illusions | $6,046 | - | 5 | - | $1,209 | $241,158 | 6 | Tartan | false | false |
| 37 | - | Pretty Persuasion | $5,756 | - | 8 | - | $719 | $60,672 | 3 | Metrodome Distribution | false | false |
| 38 | - | Ice Age: The Meltdown | $5,169 | - | 6 | - | $861 | $54,482,352 | 14 | 20th Century Fox International | false | false |
| 39 | 24 | Wah-Wah | $4,094 | -47.4% | 6 | -18 | $682 | $312,283 | 6 | Lionsgate | false | false |
| 40 | - | Enron: The Smartest Guys in the Room | $3,967 | - | 7 | - | $566 | $274,747 | 11 | Lionsgate | false | false |
| 41 | 16 | Ultraviolet | $3,806 | -95.3% | 18 | -145 | $211 | $639,134 | 3 | Sony Pictures Releasing | false | false |
| 42 | - | Muhammad: The Last Prophet 2006 Re-release | $3,719 | - | 6 | - | $619 | $80,831 | 4 | Islam Channel | false | false |
| 43 | - | Ballets Russes | $3,210 | - | 3 | - | $1,070 | $217,858 | 12 | Revolver Entertainment | false | false |
| 44 | - | Sharks 3D | $2,524 | - | 1 | - | $2,524 | $26,326 | 1 | - | true | false |
| 45 | - | Brick | $2,516 | - | 2 | - | $1,258 | $1,271,761 | 9 | Optimum Releasing | false | false |
| 46 | - | Glastonbury | $2,006 | - | 2 | - | $1,003 | $170,118 | 13 | Pathé | false | false |
| 47 | 30 | Princess Raccoon | $1,599 | +25% | 1 | - | $1,599 | $4,884 | 2 | - | false | false |
| 48 | - | Lemming | $1,506 | - | 4 | - | $376 | $406,781 | 11 | Artificial Eye | false | false |
| 49 | - | Caché | $1,445 | - | 2 | - | $722 | $2,667,906 | 24 | Artificial Eye | false | false |
| 50 | - | The Squid and the Whale | $1,297 | - | 2 | - | $648 | $1,229,887 | 14 | Sony Pictures Releasing | false | false |
