| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Da Vinci Code | $3,433,799 | -42.2% | 752 | - | $4,566 | $25,771,368 | 3 | Sony Pictures Releasing | false | false |
| 2 | 2 | X-Men: The Last Stand | $2,511,914 | -45% | 454 | +1 | $5,532 | $8,353,011 | 2 | 20th Century Fox International | false | false |
| 3 | - | When a Stranger Calls | $703,585 | - | 250 | - | $2,814 | $703,585 | 1 | Sony Pictures Releasing | true | false |
| 4 | 3 | Mission: Impossible III | $302,232 | -22.9% | 316 | -71 | $956 | $8,527,046 | 5 | United International Pictures | false | false |
| 5 | - | Fearless | $210,490 | - | 150 | - | $1,403 | $210,490 | 1 | United International Pictures | true | false |
| 6 | 4 | On Probation | $204,468 | +3.4% | 93 | -1 | $2,198 | $488,109 | 2 | N/A | false | false |
| 7 | 5 | Volver | $173,502 | -6% | 145 | -4 | $1,196 | $11,941,065 | 12 | Warner Bros. | false | false |
| 8 | 6 | Chaos | $149,459 | -12.3% | 151 | -14 | $989 | $1,717,863 | 4 | TriPictures | false | false |
| 9 | 7 | Inside Man | $145,257 | -13.6% | 152 | -47 | $955 | $7,765,706 | 8 | United International Pictures | false | false |
| 10 | - | The Mistress of Spices | $145,211 | - | 60 | - | $2,420 | $145,211 | 1 | DeAPlaneta | true | false |
| 11 | 8 | Eight Below | $128,214 | -15.1% | 195 | -23 | $657 | $3,360,543 | 6 | Buena Vista International | false | false |
| 12 | 9 | Crossing Borders | $112,022 | -14% | 96 | -30 | $1,166 | $1,447,138 | 5 | Alta Films | false | false |
| 13 | 10 | Ice Age: The Meltdown | $104,667 | -9.1% | 232 | -26 | $451 | $24,364,406 | 10 | 20th Century Fox International | false | false |
| 14 | 11 | Hard Candy | $97,823 | -7.4% | 84 | - | $1,164 | $860,120 | 4 | - | false | false |
| 15 | 14 | The Wild | $78,868 | -0.8% | 162 | -24 | $486 | $5,256,464 | 8 | Buena Vista International | false | false |
| 16 | 15 | Failure to Launch | $64,494 | -14.7% | 88 | -25 | $732 | $3,806,731 | 7 | United International Pictures | false | false |
| 17 | 13 | Rosario Tijeras | $58,444 | -26.9% | 75 | -5 | $779 | $178,157 | 2 | Manga Entertainment | false | false |
| 18 | 12 | Take the Lead | $57,085 | -29.4% | 100 | -51 | $570 | $3,050,939 | 6 | TriPictures | false | false |
| 19 | 22 | Yours, Mine & Ours | $38,307 | +15.8% | 70 | -2 | $547 | $1,778,306 | 8 | Sony Pictures Releasing | false | false |
| 20 | 19 | Nanny McPhee | $38,218 | -5.3% | 83 | -4 | $460 | $2,730,090 | 9 | United International Pictures | false | false |
