| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Da Vinci Code | $11,018,157 | - | 750 | - | $14,690 | $11,018,157 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | Mission: Impossible III | $870,277 | -54.8% | 474 | -55 | $1,836 | $7,398,560 | 3 | United International Pictures | false | false |
| 3 | 2 | Chaos | $338,570 | -51.6% | 168 | -1 | $2,015 | $1,197,867 | 2 | TriPictures | false | false |
| 4 | 3 | Inside Man | $264,446 | -43.1% | 224 | -27 | $1,180 | $7,173,463 | 6 | United International Pictures | false | false |
| 5 | 4 | Eight Below | $248,588 | -39.2% | 220 | -2 | $1,129 | $2,929,023 | 4 | Buena Vista International | false | false |
| 6 | 12 | Volver | $213,670 | +18.7% | 130 | -44 | $1,643 | $11,166,390 | 10 | Warner Bros. | false | false |
| 7 | 8 | Crossing Borders | $188,998 | -38.4% | 168 | -30 | $1,124 | $1,047,332 | 3 | Alta Films | false | false |
| 8 | 6 | Ice Age: The Meltdown | $179,170 | -43.2% | 283 | -58 | $633 | $23,685,899 | 8 | 20th Century Fox International | false | false |
| 9 | 9 | Hard Candy | $160,610 | -44.3% | 83 | -1 | $1,935 | $534,848 | 2 | - | false | false |
| 10 | 5 | Take the Lead | $149,901 | -60.1% | 200 | -58 | $749 | $2,782,697 | 4 | TriPictures | false | false |
| 11 | 7 | Failure to Launch | $140,362 | -54.4% | 160 | -49 | $877 | $3,535,079 | 5 | United International Pictures | false | false |
| 12 | 13 | The Wild | $114,532 | -32.7% | 210 | -59 | $545 | $4,933,727 | 6 | Buena Vista International | false | false |
| 13 | 11 | Lucky Number Slevin | $92,469 | -50.4% | 405 | +258 | $228 | $4,482,843 | 7 | TriPictures | false | false |
| 14 | 10 | Bee Season | $88,208 | -67.3% | 176 | -45 | $501 | $2,198,978 | 4 | 20th Century Fox International | false | false |
| 15 | - | Cake | $80,335 | - | 59 | - | $1,361 | $80,335 | 1 | - | true | false |
| 16 | 14 | Slither | $60,536 | -62.5% | 75 | -5 | $807 | $251,994 | 2 | United International Pictures | false | false |
| 17 | 19 | Nanny McPhee | $50,744 | -32.1% | 99 | -25 | $512 | $2,592,151 | 7 | United International Pictures | false | false |
| 18 | 15 | V for Vendetta | $46,340 | -64.8% | 71 | -71 | $652 | $5,374,032 | 7 | Warner Bros. | false | false |
| 19 | 18 | Yours, Mine & Ours | $43,768 | -50.5% | 79 | -8 | $554 | $1,624,580 | 6 | Sony Pictures Releasing | false | false |
| 20 | 16 | Ask the Dust | $39,710 | -64.7% | 53 | -4 | $749 | $179,936 | 2 | Filmax | false | false |
