| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | The Caiman | $1,467,051 | -39.5% | 386 | +16 | $3,800 | $5,203,633 | 2 | Sacher Distribuzione | false | false |
| 2 | - | Basic Instinct 2 | $1,367,138 | - | 384 | - | $3,560 | $1,367,138 | 1 | Warner Bros. | true | false |
| 3 | 1 | Il mio miglior nemico | $1,339,098 | -47.4% | 365 | -163 | $3,668 | $19,391,558 | 4 | Filmauro | false | false |
| 4 | - | Failure to Launch | $686,117 | - | 220 | - | $3,118 | $686,117 | 1 | United International Pictures | true | false |
| 5 | 3 | The Pink Panther | $682,560 | -45.7% | 307 | -39 | $2,223 | $2,329,283 | 2 | 20th Century Fox International | false | false |
| 6 | 5 | Notte prima degli esami | $550,180 | -34.7% | 197 | -56 | $2,792 | $13,143,833 | 7 | 01 Distribution | false | false |
| 7 | 4 | Final Destination 3 | $540,726 | -49.9% | 231 | -41 | $2,340 | $2,010,225 | 2 | Eagle Pictures | false | false |
| 8 | - | Eight Below | $503,407 | - | 159 | - | $3,166 | $527,731 | 1 | Buena Vista International | true | false |
| 9 | - | 16 Blocks | $443,388 | - | 170 | - | $2,608 | $443,388 | 1 | 01 Distribution | true | false |
| 10 | 6 | V for Vendetta | $214,177 | -61.3% | 99 | -148 | $2,163 | $2,519,248 | 3 | Warner Bros. | false | false |
| 11 | - | Factotum | $137,824 | - | 60 | - | $2,297 | $137,824 | 1 | Mikado Film | true | false |
| 12 | 11 | Our Land | $67,440 | -39.6% | 2 | -54 | $33,720 | $2,428,233 | 6 | Medusa Distribuzione | false | false |
| 13 | - | Fire at My Heart | $60,800 | - | 53 | - | $1,147 | $60,800 | 1 | Istituto Luce | true | false |
| 14 | - | Into Great Silence | $58,167 | - | 18 | - | $3,231 | $58,167 | 1 | Metacinema | true | false |
| 15 | 10 | Crash | $51,104 | -55.6% | 27 | -39 | $1,892 | $3,239,381 | 21 | Filmauro | false | false |
| 16 | 9 | Syriana | $42,747 | -69% | 25 | -54 | $1,709 | $4,340,039 | 6 | Warner Bros. | false | false |
| 17 | 7 | Wallace & Gromit: The Curse of the Were-Rabbit | $41,109 | -75.1% | 75 | -121 | $548 | $3,529,328 | 5 | United International Pictures | false | false |
| 18 | 13 | The Producers | $24,922 | -73% | 19 | -56 | $1,311 | $416,398 | 3 | Sony Pictures Releasing | false | false |
| 19 | - | Lemming | $21,815 | - | 17 | - | $1,283 | $21,815 | 1 | Lucky Red | true | false |
| 20 | 16 | The Constant Gardener | $21,370 | -48% | 17 | -2 | $1,257 | $1,054,754 | 5 | BIM Distribuzione | false | false |
