| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Volver | $1,590,775 | -26.7% | 239 | +11 | $6,655 | $4,737,369 | 2 | Warner Bros. | false | false |
| 2 | - | Firewall | $1,347,900 | - | 302 | - | $4,463 | $1,347,900 | 1 | Warner Bros. | true | false |
| 3 | 2 | Date Movie | $1,077,345 | -29% | 275 | +2 | $3,917 | $2,942,775 | 2 | 20th Century Fox International | false | false |
| 4 | - | Hostel | $1,010,738 | - | 250 | - | $4,042 | $1,010,738 | 1 | Sony Pictures Releasing | true | false |
| 5 | 4 | Crash | $520,125 | -36% | 168 | -2 | $3,095 | $8,265,945 | 11 | Manga Entertainment | false | false |
| 6 | 3 | Final Destination 3 | $469,849 | -51.7% | 252 | -3 | $1,864 | $1,673,916 | 2 | - | false | false |
| 7 | 5 | The Pink Panther | $368,926 | -50.8% | 307 | -33 | $1,201 | $8,199,195 | 5 | 20th Century Fox International | false | false |
| 8 | 6 | Zathura: A Space Adventure | $335,086 | -48.2% | 223 | -2 | $1,502 | $2,070,635 | 3 | Sony Pictures Releasing | false | false |
| 9 | 7 | Proof | $293,581 | -47.5% | 122 | - | $2,406 | $1,036,396 | 2 | Buena Vista International | false | false |
| 10 | 8 | Tristan + Isolde | $292,361 | -47.3% | 255 | -5 | $1,146 | $1,962,206 | 3 | 20th Century Fox International | false | false |
| 11 | 9 | Syriana | $232,869 | -48.3% | 204 | -2 | $1,141 | $3,344,751 | 4 | Warner Bros. | false | false |
| 12 | 10 | Sky High | $158,627 | -45.9% | 196 | -36 | $809 | $3,205,031 | 5 | Buena Vista International | false | false |
| 13 | 11 | Memoirs of a Geisha | $156,040 | -39.8% | 163 | -32 | $957 | $13,856,327 | 10 | Sony Pictures Releasing | false | false |
| 14 | - | The Rough Winds | $121,616 | - | 117 | - | $1,039 | $121,616 | 1 | Alta Films | true | false |
| 15 | 14 | Brokeback Mountain | $107,071 | -37.5% | 135 | -30 | $793 | $8,390,660 | 10 | United International Pictures | false | false |
| 16 | 13 | Good Night, and Good Luck. | $106,408 | -42.7% | 84 | -22 | $1,266 | $3,886,249 | 7 | Manga Entertainment | false | false |
| 17 | 15 | Capote | $85,163 | -41.8% | 87 | -20 | $978 | $1,770,038 | 5 | Sony Pictures Releasing | false | false |
| 18 | 12 | The Protector | $76,724 | -67.6% | 110 | -64 | $697 | $997,164 | 3 | Manga Entertainment | false | false |
| 19 | - | Tsotsi | $76,459 | - | 49 | - | $1,560 | $76,459 | 1 | Vértigo Films | true | false |
| 20 | 17 | Pride & Prejudice | $71,840 | -44.3% | 74 | -37 | $970 | $3,607,199 | 7 | United International Pictures | false | false |
